Sfoglia per Autore
A continuous-flow synthesis of 1,4-benzodiazepin-5-ones, privileged scaffolds for drug discovery.
2015-01-01 Rescigno, Donatella; Viviano, Monica; Milite, Ciro; Sbardella, Gianluca; Castellano, Sabrina
ChemInform Abstract: A Continuous-Flow Synthesis of 1,4-Benzodiazepin-5-ones, Privileged Scaffolds for Drug Discovery
2015-01-01 Viviano, Monica; Milite, Ciro; Rescigno, Donatella; Castellano, Sabrina; Sbardella, Gianluca
A continuous-flow synthesis of 1,4-benzodiazepin-5-ones, privileged scaffolds for drug discovery
2015-01-01 Viviano, Monica; Milite, Ciro; Rescigno, Donatella; Castellano, Sabrina; Sbardella, Gianluca
Identification of new inhibitors of PRMTs by a multi-substrate-adduct approach
2016-01-01 Milite, Ciro; Rescigno, Donatella; Feoli, Alessandra; Nunziata, Antonietta; Castellano, Sabrina; Sbardella, Gianluca
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL G9A INHIBITORS FROM A SCAFFOLD HOPPING APPROACH
2016-01-01 Rescigno, Donatella; Milite, Ciro; Viviano, Monica; Castellano, Sabrina; Sbardella, Gianluca
ChemInform Abstract: Progress in the Development of Lysine Methyltransferase SETD8 Inhibitors
2016-01-01 Milite, Ciro; Feoli, Alessandra; Viviano, Monica; Rescigno, Donatella; Mai, Antonello; Castellano, Sabrina; Sbardella, Gianluca
The emerging role of lysine methyltransferase SETD8 in human diseases
2016-01-01 Milite, Ciro; Feoli, Alessandra; Viviano, Monica; Rescigno, Donatella; Cianciulli, Agostino; Balzano, AMODIO LUCA; Mai, Antonello; Castellano, Sabrina; Sbardella, Gianluca
Progress in the Development of Lysine Methyltransferase SETD8 Inhibitors
2016-01-01 Milite, Ciro; Feoli, Alessandra; Viviano, Monica; Rescigno, Donatella; Mai, Antonello; Castellano, Sabrina; Sbardella, Gianluca
Design, synthesis and biological evaluation of novel G9a inhibitors with improved brain permeability from a scaffold hopping approach
2017-01-01 Rescigno, Donatella; Milite, Ciro; Viviano, Monica; Feoli, Alessandra; Castellano, Sabrina; Sbardella, Gianluca
Identification of new inhibitors of PRMTs by a multi-substrate-adduct approach
2017-01-01 Milite, Ciro; Rescigno, Donatella; Feoli, Alessandra; Cavarelli, Jean; Castellano, Sabrina; Sbardella, Gianluca
Design, synthesis and biological evaluation of new selective arginine methyltransferases (PRMTs) Inhibitors
2018-01-01 Milite, C.; Feoli, A.; Rescigno, D.; Clarke, S.; Castellano, S.; Sbardella, G.
Expanding the quinazoline ring to 3H-benzo[e][1,4]diazepine: development of new and selective G9a inhibitors
2018-01-01 Milite, C.; Feoli, A.; Rescigno, Donatella; Pisapia, Vincenzo; Cosconati, S.; Castellano, S.; Sbardella, G.
Discovery of a novel chemotype of histone lysine methyltransferase EHMT1/2 (GLP/G9a) inhibitors: rational design, synthesis, biological evaluation and co-crystal structure
2019-01-01 Milite, Ciro; Feoli, Alessandra; Horton, John R; Rescigno, Donatella; Cipriano, Alessandra; Pisapia, Vincenzo; Viviano, Monica; Pepe, Giacomo; Amendola, Giorgio; Novellino, Ettore; Cosconati, Sandro; Cheng, Xiaodong; Castellano, Sabrina; Sbardella, Gianluca
Turning Nonselective Inhibitors of Type I Protein Arginine Methyltransferases into Potent and Selective Inhibitors of Protein Arginine Methyltransferase 4 through a Deconstruction-Reconstruction and Fragment-Growing Approach
2022-01-01 Iannelli, Giulia; Milite, Ciro; Marechal, Nils; Cura, Vincent; Bonnefond, Luc; Troffer-Charlier, Nathalie; Feoli, Alessandra; Rescigno, Donatella; Wang, Yalong; Cipriano, Alessandra; Viviano, Monica; Bedford, Mark T; Cavarelli, Jean; Castellano, Sabrina; Sbardella, Gianluca
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A continuous-flow synthesis of 1,4-benzodiazepin-5-ones, privileged scaffolds for drug discovery. | 1-gen-2015 | Rescigno, Donatella; Viviano, Monica; Milite, Ciro; Sbardella, Gianluca; Castellano, Sabrina | |
| ChemInform Abstract: A Continuous-Flow Synthesis of 1,4-Benzodiazepin-5-ones, Privileged Scaffolds for Drug Discovery | 1-gen-2015 | Viviano, Monica; Milite, Ciro; Rescigno, Donatella; Castellano, Sabrina; Sbardella, Gianluca | |
| A continuous-flow synthesis of 1,4-benzodiazepin-5-ones, privileged scaffolds for drug discovery | 1-gen-2015 | Viviano, Monica; Milite, Ciro; Rescigno, Donatella; Castellano, Sabrina; Sbardella, Gianluca | |
| Identification of new inhibitors of PRMTs by a multi-substrate-adduct approach | 1-gen-2016 | Milite, Ciro; Rescigno, Donatella; Feoli, Alessandra; Nunziata, Antonietta; Castellano, Sabrina; Sbardella, Gianluca | |
| DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL G9A INHIBITORS FROM A SCAFFOLD HOPPING APPROACH | 1-gen-2016 | Rescigno, Donatella; Milite, Ciro; Viviano, Monica; Castellano, Sabrina; Sbardella, Gianluca | |
| ChemInform Abstract: Progress in the Development of Lysine Methyltransferase SETD8 Inhibitors | 1-gen-2016 | Milite, Ciro; Feoli, Alessandra; Viviano, Monica; Rescigno, Donatella; Mai, Antonello; Castellano, Sabrina; Sbardella, Gianluca | |
| The emerging role of lysine methyltransferase SETD8 in human diseases | 1-gen-2016 | Milite, Ciro; Feoli, Alessandra; Viviano, Monica; Rescigno, Donatella; Cianciulli, Agostino; Balzano, AMODIO LUCA; Mai, Antonello; Castellano, Sabrina; Sbardella, Gianluca | |
| Progress in the Development of Lysine Methyltransferase SETD8 Inhibitors | 1-gen-2016 | Milite, Ciro; Feoli, Alessandra; Viviano, Monica; Rescigno, Donatella; Mai, Antonello; Castellano, Sabrina; Sbardella, Gianluca | |
| Design, synthesis and biological evaluation of novel G9a inhibitors with improved brain permeability from a scaffold hopping approach | 1-gen-2017 | Rescigno, Donatella; Milite, Ciro; Viviano, Monica; Feoli, Alessandra; Castellano, Sabrina; Sbardella, Gianluca | |
| Identification of new inhibitors of PRMTs by a multi-substrate-adduct approach | 1-gen-2017 | Milite, Ciro; Rescigno, Donatella; Feoli, Alessandra; Cavarelli, Jean; Castellano, Sabrina; Sbardella, Gianluca | |
| Design, synthesis and biological evaluation of new selective arginine methyltransferases (PRMTs) Inhibitors | 1-gen-2018 | Milite, C.; Feoli, A.; Rescigno, D.; Clarke, S.; Castellano, S.; Sbardella, G. | |
| Expanding the quinazoline ring to 3H-benzo[e][1,4]diazepine: development of new and selective G9a inhibitors | 1-gen-2018 | Milite, C.; Feoli, A.; Rescigno, Donatella; Pisapia, Vincenzo; Cosconati, S.; Castellano, S.; Sbardella, G. | |
| Discovery of a novel chemotype of histone lysine methyltransferase EHMT1/2 (GLP/G9a) inhibitors: rational design, synthesis, biological evaluation and co-crystal structure | 1-gen-2019 | Milite, Ciro; Feoli, Alessandra; Horton, John R; Rescigno, Donatella; Cipriano, Alessandra; Pisapia, Vincenzo; Viviano, Monica; Pepe, Giacomo; Amendola, Giorgio; Novellino, Ettore; Cosconati, Sandro; Cheng, Xiaodong; Castellano, Sabrina; Sbardella, Gianluca | |
| Turning Nonselective Inhibitors of Type I Protein Arginine Methyltransferases into Potent and Selective Inhibitors of Protein Arginine Methyltransferase 4 through a Deconstruction-Reconstruction and Fragment-Growing Approach | 1-gen-2022 | Iannelli, Giulia; Milite, Ciro; Marechal, Nils; Cura, Vincent; Bonnefond, Luc; Troffer-Charlier, Nathalie; Feoli, Alessandra; Rescigno, Donatella; Wang, Yalong; Cipriano, Alessandra; Viviano, Monica; Bedford, Mark T; Cavarelli, Jean; Castellano, Sabrina; Sbardella, Gianluca |
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