Beside tremasterols A-C, the first phosphated steroid glycosides to be found from a natural source, the starfish Tremaster novaecaledoniae contains nine more novel steroid constituents. One, is related to the previous tremasterols by having the same 6-O-phosphated function. A second group of 4 compds. possesses the same 3,6-disulfated 3β,6α-(22R)-trihydroxycholestane structure, differing by the presence of the Δ9(11) double bond in 2 compds. and by the acetate conjugation of the 22-hydroxyl group in the 2 other compds. The remaining 4 compds. are highly hydroxylated steroids, including one that features the cis A/B ring junction, never encountered before among steroids derived from starfishes.

Phosphated and sulfated marine polyhydroxylated steroids from the starfish Tremaster novaecaledoniae

DE RICCARDIS, Francesco;RICCIO, Raffaele;
1993-01-01

Abstract

Beside tremasterols A-C, the first phosphated steroid glycosides to be found from a natural source, the starfish Tremaster novaecaledoniae contains nine more novel steroid constituents. One, is related to the previous tremasterols by having the same 6-O-phosphated function. A second group of 4 compds. possesses the same 3,6-disulfated 3β,6α-(22R)-trihydroxycholestane structure, differing by the presence of the Δ9(11) double bond in 2 compds. and by the acetate conjugation of the 22-hydroxyl group in the 2 other compds. The remaining 4 compds. are highly hydroxylated steroids, including one that features the cis A/B ring junction, never encountered before among steroids derived from starfishes.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11386/3128293
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