Abstract: Six novel cycloartane-type glycosides were isolated from the roots of Astragalus trojanus. Two of these, compounds 1 and 2, have (20R,24S)-epoxy-3β,6α,16β,25-tetrahydroxycycloartane as the aglycon, while compounds 3−6 possess 3β,6α,16β,(24S),25-pentahydroxycycloartane as the aglycon. The saccharide moieties linked to the C-3, C-6, and C-24 or C-25 positions of the aglycons in 1−6 contained either xylopyranose, glucopyranose, rhamnopyranose, or arabinopyranose units. Structure elucidation of compounds 1−6 was accomplished through the extensive use of 1D and 2D NMR techniques. In addition, a new oleanene glycoside (7) and a new tryptophan derivative (8) were also isolated and characterized.

Secondary Metabolites from the Roots of Astragalus trojanus

AQUINO, Rita Patrizia;PIACENTE, Sonia;PIZZA, Cosimo
1999-01-01

Abstract

Abstract: Six novel cycloartane-type glycosides were isolated from the roots of Astragalus trojanus. Two of these, compounds 1 and 2, have (20R,24S)-epoxy-3β,6α,16β,25-tetrahydroxycycloartane as the aglycon, while compounds 3−6 possess 3β,6α,16β,(24S),25-pentahydroxycycloartane as the aglycon. The saccharide moieties linked to the C-3, C-6, and C-24 or C-25 positions of the aglycons in 1−6 contained either xylopyranose, glucopyranose, rhamnopyranose, or arabinopyranose units. Structure elucidation of compounds 1−6 was accomplished through the extensive use of 1D and 2D NMR techniques. In addition, a new oleanene glycoside (7) and a new tryptophan derivative (8) were also isolated and characterized.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11386/3137433
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