Sfoglia per Autore PACE, Simona
A class of pyrrole derivatives endowed with analgesic/anti-inflammatory activity
2013-01-01 Battilocchio, Claudio; Poce, Giovanna; Alfonso, Salvatore; Porretta, Giulio Cesare; Consalvi, Sara; Sautebin, Lidia; Pace, Simona; Rossi, Antonietta; Ghelardini, Carla; Di Cesare Mannelli, Lorenzo; Schenone, Silvia; Giordani, Antonio; Di Francesco, Luigia; Patrignani, Paola; Biava, Mariangela
Novel analgesic/anti-inflammatory agents: 1,5-diarylpyrrole nitrooxyalkyl ethers and related compounds as cyclooxygenase-2 inhibiting nitric oxide donors
2013-01-01 Anzini, Maurizio; Di Capua, Angela; Valenti, Salvatore; Brogi, Simone; Rovini, Michele; Giuliani, Germano; Cappelli, Andrea; Vomero, Salvatore; Chiasserini, Luisa; Sega, Alessandro; Poce, Giovanna; Giorgi, Gianluca; Calderone, Vincenzo; Martelli, Alma; Testai, Lara; Sautebin, Lidia; Rossi, Antonietta; Pace, Simona; Ghelardini, Carla; Di Cesare Mannelli, Lorenzo; Benetti, Veronica; Giordani, Antonio; Anzellotti, Paola; Dovizio, Melania; Patrignani, Paola; Biava, Mariangela
In vivo sex differences in leukotriene biosynthesis in zymosan-induced peritonitis
2014-01-01 Rossi, Antonietta; Pergola, Carlo; Pace, Simona; Rådmark, Olof; Werz, Oliver; Sautebin, Lidia
The chemopreventive action of bromelain, from pineapple stem (Ananas comosus L.), on colon carcinogenesis is related to antiproliferative and proapoptotic effects
2014-01-01 Romano, Barbara; Fasolino, Ines; Pagano, Ester; Capasso, Raffaele; Pace, Simona; De Rosa, Giuseppe; Milic, Natasa; Orlando, Pierangelo; Izzo, Angelo A; Borrelli, Francesca
The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP)
2014-01-01 Pergola, C; Gerstmeier, J; Mönch, B; Çalışkan, B; Luderer, S; Weinigel, C; Barz, D; Maczewsky, J; Pace, S; Rossi, A; Sautebin, L; Banoglu, E; Werz, O
SAR studies on curcumin's pro-inflammatory targets: discovery of prenylated pyrazolocurcuminoids as potent and selective novel inhibitors of 5-lipoxygenase
2014-01-01 Koeberle, Andreas; Muñoz, Eduardo; Appendino, Giovanni B; Minassi, Alberto; Pace, Simona; Rossi, Antonietta; Weinigel, Christina; Barz, Dagmar; Sautebin, Lidia; Caprioglio, Diego; Collado, Juan A; Werz, Oliver
Use of Mometasone furoate in prolonged treatment of experimental spinal cord injury in mice: A comparative study of three different glucocorticoids
2015-01-01 Galuppo, Maria; Rossi, Antonietta; Giacoppo, Sabrina; Pace, Simona; Bramanti, Placido; Sautebin, Lidia; Mazzon, Emanuela
The hallucinogenic diterpene salvinorin A inhibits leukotriene synthesis in experimental models of inflammation
2016-01-01 Rossi, Antonietta; Pace, Simona; Tedesco, Federica; Pagano, Ester; Guerra, Germano; Troisi, Fabiana; Werner, Markus; Roviezzo, Fiorentina; Zjawiony, Jordan K; Werz, Oliver; Izzo, Angelo A; Capasso, Raffaele
BRP-187: A potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5-lipoxygenase/5-lipoxygenase-activating protein (FLAP) complex assembly
2016-01-01 Garscha, Ulrike; Voelker, Susanna; Pace, Simona; Gerstmeier, Jana; Emini, Besa; Liening, Stefanie; Rossi, Antonietta; Weinigel, Christina; Rummler, Silke; Schubert, Ulrich S; Scriba, Gerhard K E; Çelikoğlu, Erşan; Çalışkan, Burcu; Banoglu, Erden; Sautebin, Lidia; Werz, Oliver
The 5-lipoxygenase inhibitor RF-22c potently suppresses leukotriene biosynthesis in cellulo and blocks bronchoconstriction and inflammation in vivo
2016-01-01 Schaible, Anja M; Filosa, Rosanna; Krauth, Verena; Temml, Veronika; Pace, Simona; Garscha, Ulrike; Liening, Stefanie; Weinigel, Christina; Rummler, Silke; Schieferdecker, Sebastian; Nett, Markus; Peduto, Antonella; Collarile, Selene; Scuotto, Maria; Roviezzo, Fioretina; Spaziano, Giuseppe; de Rosa, Mario; Stuppner, Hermann; Schuster, Daniela; D'Agostino, Bruno; Werz, Oliver
Humudifucol and Bioactive Prenylated Polyphenols from Hops (Humulus lupulus cv. "Cascade")
2016-01-01 Forino, Martino; Pace, Simona; Chianese, Giuseppina; Santagostini, Laura; Werner, Markus; Weinigel, Christina; Rummler, Silke; Fico, Gelsomina; Werz, Oliver; Taglialatela-Scafati, Orazio
Synthesis and biological evaluation of fluorinated 1,5-diarylpyrrole-3-alkoxyethyl ether derivatives as selective COX-2 inhibitors endowed with anti-inflammatory activity
2016-01-01 Di Capua, Angela; Sticozzi, Claudia; Brogi, Simone; Brindisi, Margherita; Cappelli, Andrea; Sautebin, Lidia; Rossi, Antonietta; Pace, Simona; Ghelardini, Carla; Di Cesare Mannelli, Lorenzo; Valacchi, Giuseppe; Giorgi, Gianluca; Giordani, Antonio; Poce, Giovanna; Biava, Mariangela; Anzini, Maurizio
Modulation of actin dynamics as potential macrophage subtype-targeting anti-tumour strategy
2017-01-01 Pergola, Carlo; Schubert, Katrin; Pace, Simona; Ziereisen, Jana; Nikels, Felix; Scherer, Olga; Hüttel, Stephan; Zahler, Stefan; Vollmar, Angelika M; Weinigel, Christina; Rummler, Silke; Müller, Rolf; Raasch, Martin; Mosig, Alexander; Koeberle, Andreas; Werz, Oliver
Androgen-mediated sex bias impairs efficiency of leukotriene biosynthesis inhibitors in males
2017-01-01 Pace, Simona; Pergola, Carlo; Dehm, Friederike; Rossi, Antonietta; Gerstmeier, Jana; Troisi, Fabiana; Pein, Helmut; Schaible, Anja M; Weinigel, Christina; Rummler, Silke; Northoff, Hinnak; Laufer, Stefan; Maier, Thorsten J; Rådmark, Olof; Samuelsson, Bengt; Koeberle, Andreas; Sautebin, Lidia; Werz, Oliver
NMR-based identification of the major bioactive molecules from an Italian cultivar of Lycium barbarum
2017-01-01 Lopatriello, Annalisa; Previtera, Rosario; Pace, Simona; Werner, Markus; Rubino, Luigi; Werz, Oliver; Taglialatela-Scafati, Orazio; Forino, Martino
Sex-biased eicosanoid biology: Impact for sex differences in inflammation and consequences for pharmacotherapy
2017-01-01 Pace, Simona; Sautebin, Lidia; Werz, Oliver
Pharmacological profile and efficiency in vivo of diflapolin, the first dual inhibitor of 5-lipoxygenase-activating protein and soluble epoxide hydrolase
2017-01-01 Garscha, Ulrike; Romp, Erik; Pace, Simona; Rossi, Antonietta; Temml, Veronika; Schuster, Daniela; König, Stefanie; Gerstmeier, Jana; Liening, Stefanie; Werner, Markus; Atze, Heiner; Wittmann, Sandra; Weinigel, Christina; Rummler, Silke; Scriba, Gerhard K; Sautebin, Lidia; Werz, Oliver
Evaluation of Dual 5-Lipoxygenase/Microsomal Prostaglandin E2 Synthase-1 Inhibitory Effect of Natural and Synthetic Acronychia-Type Isoprenylated Acetophenones
2017-01-01 Svouraki, Alexandra; Garscha, Ulrike; Kouloura, Eirini; Pace, Simona; Pergola, Carlo; Krauth, Verena; Rossi, Antonietta; Sautebin, Lidia; Halabalaki, Maria; Werz, Oliver; Gaboriaud-Kolar, Nicolas; Skaltsounis, Alexios-Leandros
Myxochelin-Inspired 5-Lipoxygenase Inhibitors: Synthesis and Biological Evaluation
2017-01-01 Schieferdecker, Sebastian; König, Stefanie; Pace, Simona; Werz, Oliver; Nett, Markus
Sex differences in prostaglandin biosynthesis in neutrophils during acute inflammation
2017-01-01 Pace, Simona; Rossi, Antonietta; Krauth, Verena; Dehm, Friederike; Troisi, Fabiana; Bilancia, Rossella; Weinigel, Christina; Rummler, Silke; Werz, Oliver; Sautebin, Lidia
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A class of pyrrole derivatives endowed with analgesic/anti-inflammatory activity | 1-gen-2013 | Battilocchio, Claudio; Poce, Giovanna; Alfonso, Salvatore; Porretta, Giulio Cesare; Consalvi, Sara; Sautebin, Lidia; Pace, Simona; Rossi, Antonietta; Ghelardini, Carla; Di Cesare Mannelli, Lorenzo; Schenone, Silvia; Giordani, Antonio; Di Francesco, Luigia; Patrignani, Paola; Biava, Mariangela | |
| Novel analgesic/anti-inflammatory agents: 1,5-diarylpyrrole nitrooxyalkyl ethers and related compounds as cyclooxygenase-2 inhibiting nitric oxide donors | 1-gen-2013 | Anzini, Maurizio; Di Capua, Angela; Valenti, Salvatore; Brogi, Simone; Rovini, Michele; Giuliani, Germano; Cappelli, Andrea; Vomero, Salvatore; Chiasserini, Luisa; Sega, Alessandro; Poce, Giovanna; Giorgi, Gianluca; Calderone, Vincenzo; Martelli, Alma; Testai, Lara; Sautebin, Lidia; Rossi, Antonietta; Pace, Simona; Ghelardini, Carla; Di Cesare Mannelli, Lorenzo; Benetti, Veronica; Giordani, Antonio; Anzellotti, Paola; Dovizio, Melania; Patrignani, Paola; Biava, Mariangela | |
| In vivo sex differences in leukotriene biosynthesis in zymosan-induced peritonitis | 1-gen-2014 | Rossi, Antonietta; Pergola, Carlo; Pace, Simona; Rådmark, Olof; Werz, Oliver; Sautebin, Lidia | |
| The chemopreventive action of bromelain, from pineapple stem (Ananas comosus L.), on colon carcinogenesis is related to antiproliferative and proapoptotic effects | 1-gen-2014 | Romano, Barbara; Fasolino, Ines; Pagano, Ester; Capasso, Raffaele; Pace, Simona; De Rosa, Giuseppe; Milic, Natasa; Orlando, Pierangelo; Izzo, Angelo A; Borrelli, Francesca | |
| The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP) | 1-gen-2014 | Pergola, C; Gerstmeier, J; Mönch, B; Çalışkan, B; Luderer, S; Weinigel, C; Barz, D; Maczewsky, J; Pace, S; Rossi, A; Sautebin, L; Banoglu, E; Werz, O | |
| SAR studies on curcumin's pro-inflammatory targets: discovery of prenylated pyrazolocurcuminoids as potent and selective novel inhibitors of 5-lipoxygenase | 1-gen-2014 | Koeberle, Andreas; Muñoz, Eduardo; Appendino, Giovanni B; Minassi, Alberto; Pace, Simona; Rossi, Antonietta; Weinigel, Christina; Barz, Dagmar; Sautebin, Lidia; Caprioglio, Diego; Collado, Juan A; Werz, Oliver | |
| Use of Mometasone furoate in prolonged treatment of experimental spinal cord injury in mice: A comparative study of three different glucocorticoids | 1-gen-2015 | Galuppo, Maria; Rossi, Antonietta; Giacoppo, Sabrina; Pace, Simona; Bramanti, Placido; Sautebin, Lidia; Mazzon, Emanuela | |
| The hallucinogenic diterpene salvinorin A inhibits leukotriene synthesis in experimental models of inflammation | 1-gen-2016 | Rossi, Antonietta; Pace, Simona; Tedesco, Federica; Pagano, Ester; Guerra, Germano; Troisi, Fabiana; Werner, Markus; Roviezzo, Fiorentina; Zjawiony, Jordan K; Werz, Oliver; Izzo, Angelo A; Capasso, Raffaele | |
| BRP-187: A potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5-lipoxygenase/5-lipoxygenase-activating protein (FLAP) complex assembly | 1-gen-2016 | Garscha, Ulrike; Voelker, Susanna; Pace, Simona; Gerstmeier, Jana; Emini, Besa; Liening, Stefanie; Rossi, Antonietta; Weinigel, Christina; Rummler, Silke; Schubert, Ulrich S; Scriba, Gerhard K E; Çelikoğlu, Erşan; Çalışkan, Burcu; Banoglu, Erden; Sautebin, Lidia; Werz, Oliver | |
| The 5-lipoxygenase inhibitor RF-22c potently suppresses leukotriene biosynthesis in cellulo and blocks bronchoconstriction and inflammation in vivo | 1-gen-2016 | Schaible, Anja M; Filosa, Rosanna; Krauth, Verena; Temml, Veronika; Pace, Simona; Garscha, Ulrike; Liening, Stefanie; Weinigel, Christina; Rummler, Silke; Schieferdecker, Sebastian; Nett, Markus; Peduto, Antonella; Collarile, Selene; Scuotto, Maria; Roviezzo, Fioretina; Spaziano, Giuseppe; de Rosa, Mario; Stuppner, Hermann; Schuster, Daniela; D'Agostino, Bruno; Werz, Oliver | |
| Humudifucol and Bioactive Prenylated Polyphenols from Hops (Humulus lupulus cv. "Cascade") | 1-gen-2016 | Forino, Martino; Pace, Simona; Chianese, Giuseppina; Santagostini, Laura; Werner, Markus; Weinigel, Christina; Rummler, Silke; Fico, Gelsomina; Werz, Oliver; Taglialatela-Scafati, Orazio | |
| Synthesis and biological evaluation of fluorinated 1,5-diarylpyrrole-3-alkoxyethyl ether derivatives as selective COX-2 inhibitors endowed with anti-inflammatory activity | 1-gen-2016 | Di Capua, Angela; Sticozzi, Claudia; Brogi, Simone; Brindisi, Margherita; Cappelli, Andrea; Sautebin, Lidia; Rossi, Antonietta; Pace, Simona; Ghelardini, Carla; Di Cesare Mannelli, Lorenzo; Valacchi, Giuseppe; Giorgi, Gianluca; Giordani, Antonio; Poce, Giovanna; Biava, Mariangela; Anzini, Maurizio | |
| Modulation of actin dynamics as potential macrophage subtype-targeting anti-tumour strategy | 1-gen-2017 | Pergola, Carlo; Schubert, Katrin; Pace, Simona; Ziereisen, Jana; Nikels, Felix; Scherer, Olga; Hüttel, Stephan; Zahler, Stefan; Vollmar, Angelika M; Weinigel, Christina; Rummler, Silke; Müller, Rolf; Raasch, Martin; Mosig, Alexander; Koeberle, Andreas; Werz, Oliver | |
| Androgen-mediated sex bias impairs efficiency of leukotriene biosynthesis inhibitors in males | 1-gen-2017 | Pace, Simona; Pergola, Carlo; Dehm, Friederike; Rossi, Antonietta; Gerstmeier, Jana; Troisi, Fabiana; Pein, Helmut; Schaible, Anja M; Weinigel, Christina; Rummler, Silke; Northoff, Hinnak; Laufer, Stefan; Maier, Thorsten J; Rådmark, Olof; Samuelsson, Bengt; Koeberle, Andreas; Sautebin, Lidia; Werz, Oliver | |
| NMR-based identification of the major bioactive molecules from an Italian cultivar of Lycium barbarum | 1-gen-2017 | Lopatriello, Annalisa; Previtera, Rosario; Pace, Simona; Werner, Markus; Rubino, Luigi; Werz, Oliver; Taglialatela-Scafati, Orazio; Forino, Martino | |
| Sex-biased eicosanoid biology: Impact for sex differences in inflammation and consequences for pharmacotherapy | 1-gen-2017 | Pace, Simona; Sautebin, Lidia; Werz, Oliver | |
| Pharmacological profile and efficiency in vivo of diflapolin, the first dual inhibitor of 5-lipoxygenase-activating protein and soluble epoxide hydrolase | 1-gen-2017 | Garscha, Ulrike; Romp, Erik; Pace, Simona; Rossi, Antonietta; Temml, Veronika; Schuster, Daniela; König, Stefanie; Gerstmeier, Jana; Liening, Stefanie; Werner, Markus; Atze, Heiner; Wittmann, Sandra; Weinigel, Christina; Rummler, Silke; Scriba, Gerhard K; Sautebin, Lidia; Werz, Oliver | |
| Evaluation of Dual 5-Lipoxygenase/Microsomal Prostaglandin E2 Synthase-1 Inhibitory Effect of Natural and Synthetic Acronychia-Type Isoprenylated Acetophenones | 1-gen-2017 | Svouraki, Alexandra; Garscha, Ulrike; Kouloura, Eirini; Pace, Simona; Pergola, Carlo; Krauth, Verena; Rossi, Antonietta; Sautebin, Lidia; Halabalaki, Maria; Werz, Oliver; Gaboriaud-Kolar, Nicolas; Skaltsounis, Alexios-Leandros | |
| Myxochelin-Inspired 5-Lipoxygenase Inhibitors: Synthesis and Biological Evaluation | 1-gen-2017 | Schieferdecker, Sebastian; König, Stefanie; Pace, Simona; Werz, Oliver; Nett, Markus | |
| Sex differences in prostaglandin biosynthesis in neutrophils during acute inflammation | 1-gen-2017 | Pace, Simona; Rossi, Antonietta; Krauth, Verena; Dehm, Friederike; Troisi, Fabiana; Bilancia, Rossella; Weinigel, Christina; Rummler, Silke; Werz, Oliver; Sautebin, Lidia |
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