CHINI, MARIA GIOVANNA
CHINI, MARIA GIOVANNA
Dipartimento di Farmacia/DIFARMA
2-Substituted 1,5-benzothiazepine-based HDAC inhibitors exert anticancer activities on human solid and acute myeloid leukemia cell lines
2023-01-01 De Vita, Simona; Meninno, Sara; Capasso, Lucia; Colarusso, Ester; Chini, Maria Giovanna; Lauro, Gianluigi; Rinaldi, Romolo; De Cicco, Annalisa; Sian, Veronica; Terracciano, Stefania; Nebbioso, Angela; Lattanzi, Alessandra; Bifulco, Giuseppe
4-Methylenesterols from Theonella swinhoei sponge are natural pregnane-X-receptor agonists and farnesoid-X-receptor antagonists that modulate innate immunity
2012-01-01 Simona De, Marino; Raffaella, Ummarino; Maria Valeria, D’Auria; Chini, MARIA GIOVANNA; Bifulco, Giuseppe; Claudio, D’Amore; Barbara, Renga; Andrea, Mencarelli; Sylvain, Petek; Stefano, Fiorucci; Angela, Zampella
A Chemical-Biological Study Reveals C-9-type Iridoids as Novel Heat Shock Protein 90 (Hsp90) Inhibitors
2013-01-01 DAL PIAZ, Fabrizio; Vassallo, A.; Temraz, A.; Cotugno, Roberta; Belisario, MARIA ANTONIETTA; Bifulco, Giuseppe; Chini, MARIA GIOVANNA; Pisano, C.; DE TOMMASI, Nunziatina; Braca, A.
A Novel Potent Nicotinamide Phosphoribosyltransferase Inhibitor Synthesized via Click Chemistry
2010-01-01 G., Colombano; C., Travelli; U., Galli; A., Caldarelli; Chini, MARIA GIOVANNA; P. L., Canonico; G., Sorba; Bifulco, Giuseppe; G. C., Tron; A. A., Genazzani
Anti-inflammatory and analgesic activity of carnosol and carnosic acid in vivo and in vitro and in silico analysis of their target interactions
2017-01-01 Maione, Francesco; Cantone, Vincenza; Pace, Simona; Chini, MARIA GIOVANNA; Bisio, Angela; Romussi, Giovanni; Pieretti, Stefano; Werz, Oliver; Koeberle, Andreas; Mascolo, Nicola; Bifulco, Giuseppe
Can Small Chemical Modifications of Natural Pan-inhibitors Modulate the Biological Selectivity? the Case of Curcumin Prenylated Derivatives Acting as HDAC or mPGES-1 Inhibitors
2015-01-01 Iranshahi, Mehrdad; Chini, MARIA GIOVANNA; Masullo, Milena; Sahebkar, Amirhossein; Javidnia, Azita; Chitsazian Yazdi, Mahsa; Pergola, Carlo; Koeberle, Andreas; Werz, Oliver; Pizza, Cosimo; Terracciano, Stefania; Piacente, Sonia; Bifulco, Giuseppe
Carnosol Attenuates LPS-Induced Inflammation of Cardiomyoblasts by Inhibiting NF-κB: A Mechanistic in Vitro and in Silico Study
2022-01-01 Baradaran Rahimi, Vafa; Momeni-Moghaddam, Mohammad Amin; Chini, Maria Giovanna; Saviano, Anella; Maione, Francesco; Bifulco, Giuseppe; Rahmanian-Devin, Pouria; Jebalbarezy, Ali; Askari, Vahid Reza
Chemoproteomics Reveals USP5 (Ubiquitin Carboxyl-Terminal Hydrolase 5) as Promising Target of the Marine Polyketide Gracilioether A
2024-01-01 Capuano, A.; D'Urso, G.; Aliberti, M.; Ruggiero, D.; Terracciano, S.; Festa, C.; Tosco, A.; Chini, M. G.; Lauro, G.; Bifulco, G.; Casapullo, A.
Computational NMR Methods in the Stereochemical Analysis of Organic Compounds: Are Proton or Carbon NMR Chemical Shift Data More Discriminating?
2015-01-01 Chini, MARIA GIOVANNA; Riccio, Raffaele; Bifulco, Giuseppe
Conformationally locked calixarene-based histone deacetylase inhibitors
2010-01-01 Chini, MARIA GIOVANNA; Terracciano, Stefania; Riccio, Raffaele; Bifulco, Giuseppe; Ciao, Roberta; Gaeta, Carmine; Troisi, Francesco; Neri, Placido
Conicasterol E, a Small Heterodimer Partner Sparing Farnesoid X Receptor Modulator Endowed with a Pregnane X Receptor Agonistic Activity, from the Marine SpongeTheonella swinhoei
2012-01-01 Valentina, Sepe; Raffaella, Ummarino; Maria Valeria, D’Auria; Chini, MARIA GIOVANNA; Bifulco, Giuseppe; Barbara, Renga; Claudio, D’Amore; Cécile, Debitus; Stefano, Fiorucci; Angela, Zampella
Correction: Identification of the key structural elements of a dihydropyrimidinone core driving toward more potent Hsp90 C-terminal inhibitors
2016-01-01 Terracciano, Stefania; Chini, Maria Giovanna; Vaccaro, Mariacarmela; Strocchia, Maria; Foglia, Antonio; Vassallo, Antonio; Saturnino, Carmela; Riccio, Raffaele; Bifulco, Giuseppe; Bruno, Ines
Design and synthesis of a second series of triazole-based compounds as potent dual mPGES-1 and 5-lipoxygenase inhibitors
2012-01-01 Chini, MARIA GIOVANNA; Rosa De, Simone; Bruno, Ines; Riccio, Raffaele; Friederike, Dehm; Christina, Weinigel; Dagmar, Barz; Oliver, Werz; Bifulco, Giuseppe
Design, synthesis and biological evaluation of pyrrole derivatives as coactivator associated arginine methyltransferase 1 (CARM1) inhibitors
2015-01-01 Cianciulli, Agostino; Milite, Ciro; Castellano, Sabrina; Chini, MARIA GIOVANNA; Bifulco, Giuseppe; Xu, Wei; Sbardella, Gianluca
Design, Synthesis, and Biological Activity of Hydroxamic Tertiary Amines as Histone Deacetylase Inhibitors
2012-01-01 Terracciano, Stefania; Chini, MARIA GIOVANNA; Riccio, Raffaele; Bruno, Ines; Bifulco, Giuseppe
Dimeric and trimeric triazole based molecules as a new class of Hsp90 molecular chaperone inhibitors
2013-01-01 Terracciano, Stefania; Chini, MARIA GIOVANNA; DAL PIAZ, Fabrizio; Antonio, Vassallo; Riccio, Raffaele; Bruno, Ines; Bifulco, Giuseppe
Discovery of new molecular entities able to strongly interfere with Hsp90 C-terminal domain
2018-01-01 Terracciano, Stefania; Russo, Alessandra; Chini, Maria G.; Vaccaro, Maria C.; Potenza, Marianna; Vassallo, Antonio; Riccio, Raffaele; Bifulco, Giuseppe; Bruno, Ines
Discovery That Theonellasterol a Marine Sponge Sterol Is a Highly Selective FXR Antagonist That Protects against Liver Injury in Cholestasis
2012-01-01 Barbara, Renga; Andrea, Mencarelli; Claudio, D'Amore; Sabrina, Cipriani; Maria Valeria, D'Auria; Valentina, Sepe; Chini, MARIA GIOVANNA; Monti, Maria Chiara; Bifulco, Giuseppe; Angela, Zampella; Stefano, Fiorucci
Diterpenoids from Zhumeria majdae roots as potential heat shock protein 90 (HSP90) modulators
2021-01-01 Zadali, R.; Nejad-Ebrahimi, S.; Hadjiakhoondi, A.; Fiengo, L.; D'Ambola, M.; De Vita, S.; Tofighi, Z.; Chini, M. G.; Bifulco, G.; De Tommasi, N.
Down regulation of pro-inflammatory pathways by tanshinone IIA and cryptotanshinone in a non-genetic mouse model of Alzheimer's disease
2018-01-01 Maione, Francesco; Piccolo, Marialuisa; DE VITA, Simona; Chini, Maria Giovanna; Cristiano, Claudia; De Caro, Carmen; Lippiello, Pellegrino; Miniaci, Maria Concetta; Santamaria, Rita; Irace, Carlo; De Feo, Vincenzo; Calignano, Antonio; Mascolo, Nicola; Bifulco, Giuseppe
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 2-Substituted 1,5-benzothiazepine-based HDAC inhibitors exert anticancer activities on human solid and acute myeloid leukemia cell lines | 1-gen-2023 | De Vita, Simona; Meninno, Sara; Capasso, Lucia; Colarusso, Ester; Chini, Maria Giovanna; Lauro, Gianluigi; Rinaldi, Romolo; De Cicco, Annalisa; Sian, Veronica; Terracciano, Stefania; Nebbioso, Angela; Lattanzi, Alessandra; Bifulco, Giuseppe | |
| 4-Methylenesterols from Theonella swinhoei sponge are natural pregnane-X-receptor agonists and farnesoid-X-receptor antagonists that modulate innate immunity | 1-gen-2012 | Simona De, Marino; Raffaella, Ummarino; Maria Valeria, D’Auria; Chini, MARIA GIOVANNA; Bifulco, Giuseppe; Claudio, D’Amore; Barbara, Renga; Andrea, Mencarelli; Sylvain, Petek; Stefano, Fiorucci; Angela, Zampella | |
| A Chemical-Biological Study Reveals C-9-type Iridoids as Novel Heat Shock Protein 90 (Hsp90) Inhibitors | 1-gen-2013 | DAL PIAZ, Fabrizio; Vassallo, A.; Temraz, A.; Cotugno, Roberta; Belisario, MARIA ANTONIETTA; Bifulco, Giuseppe; Chini, MARIA GIOVANNA; Pisano, C.; DE TOMMASI, Nunziatina; Braca, A. | |
| A Novel Potent Nicotinamide Phosphoribosyltransferase Inhibitor Synthesized via Click Chemistry | 1-gen-2010 | G., Colombano; C., Travelli; U., Galli; A., Caldarelli; Chini, MARIA GIOVANNA; P. L., Canonico; G., Sorba; Bifulco, Giuseppe; G. C., Tron; A. A., Genazzani | |
| Anti-inflammatory and analgesic activity of carnosol and carnosic acid in vivo and in vitro and in silico analysis of their target interactions | 1-gen-2017 | Maione, Francesco; Cantone, Vincenza; Pace, Simona; Chini, MARIA GIOVANNA; Bisio, Angela; Romussi, Giovanni; Pieretti, Stefano; Werz, Oliver; Koeberle, Andreas; Mascolo, Nicola; Bifulco, Giuseppe | |
| Can Small Chemical Modifications of Natural Pan-inhibitors Modulate the Biological Selectivity? the Case of Curcumin Prenylated Derivatives Acting as HDAC or mPGES-1 Inhibitors | 1-gen-2015 | Iranshahi, Mehrdad; Chini, MARIA GIOVANNA; Masullo, Milena; Sahebkar, Amirhossein; Javidnia, Azita; Chitsazian Yazdi, Mahsa; Pergola, Carlo; Koeberle, Andreas; Werz, Oliver; Pizza, Cosimo; Terracciano, Stefania; Piacente, Sonia; Bifulco, Giuseppe | |
| Carnosol Attenuates LPS-Induced Inflammation of Cardiomyoblasts by Inhibiting NF-κB: A Mechanistic in Vitro and in Silico Study | 1-gen-2022 | Baradaran Rahimi, Vafa; Momeni-Moghaddam, Mohammad Amin; Chini, Maria Giovanna; Saviano, Anella; Maione, Francesco; Bifulco, Giuseppe; Rahmanian-Devin, Pouria; Jebalbarezy, Ali; Askari, Vahid Reza | |
| Chemoproteomics Reveals USP5 (Ubiquitin Carboxyl-Terminal Hydrolase 5) as Promising Target of the Marine Polyketide Gracilioether A | 1-gen-2024 | Capuano, A.; D'Urso, G.; Aliberti, M.; Ruggiero, D.; Terracciano, S.; Festa, C.; Tosco, A.; Chini, M. G.; Lauro, G.; Bifulco, G.; Casapullo, A. | |
| Computational NMR Methods in the Stereochemical Analysis of Organic Compounds: Are Proton or Carbon NMR Chemical Shift Data More Discriminating? | 1-gen-2015 | Chini, MARIA GIOVANNA; Riccio, Raffaele; Bifulco, Giuseppe | |
| Conformationally locked calixarene-based histone deacetylase inhibitors | 1-gen-2010 | Chini, MARIA GIOVANNA; Terracciano, Stefania; Riccio, Raffaele; Bifulco, Giuseppe; Ciao, Roberta; Gaeta, Carmine; Troisi, Francesco; Neri, Placido | |
| Conicasterol E, a Small Heterodimer Partner Sparing Farnesoid X Receptor Modulator Endowed with a Pregnane X Receptor Agonistic Activity, from the Marine SpongeTheonella swinhoei | 1-gen-2012 | Valentina, Sepe; Raffaella, Ummarino; Maria Valeria, D’Auria; Chini, MARIA GIOVANNA; Bifulco, Giuseppe; Barbara, Renga; Claudio, D’Amore; Cécile, Debitus; Stefano, Fiorucci; Angela, Zampella | |
| Correction: Identification of the key structural elements of a dihydropyrimidinone core driving toward more potent Hsp90 C-terminal inhibitors | 1-gen-2016 | Terracciano, Stefania; Chini, Maria Giovanna; Vaccaro, Mariacarmela; Strocchia, Maria; Foglia, Antonio; Vassallo, Antonio; Saturnino, Carmela; Riccio, Raffaele; Bifulco, Giuseppe; Bruno, Ines | |
| Design and synthesis of a second series of triazole-based compounds as potent dual mPGES-1 and 5-lipoxygenase inhibitors | 1-gen-2012 | Chini, MARIA GIOVANNA; Rosa De, Simone; Bruno, Ines; Riccio, Raffaele; Friederike, Dehm; Christina, Weinigel; Dagmar, Barz; Oliver, Werz; Bifulco, Giuseppe | |
| Design, synthesis and biological evaluation of pyrrole derivatives as coactivator associated arginine methyltransferase 1 (CARM1) inhibitors | 1-gen-2015 | Cianciulli, Agostino; Milite, Ciro; Castellano, Sabrina; Chini, MARIA GIOVANNA; Bifulco, Giuseppe; Xu, Wei; Sbardella, Gianluca | |
| Design, Synthesis, and Biological Activity of Hydroxamic Tertiary Amines as Histone Deacetylase Inhibitors | 1-gen-2012 | Terracciano, Stefania; Chini, MARIA GIOVANNA; Riccio, Raffaele; Bruno, Ines; Bifulco, Giuseppe | |
| Dimeric and trimeric triazole based molecules as a new class of Hsp90 molecular chaperone inhibitors | 1-gen-2013 | Terracciano, Stefania; Chini, MARIA GIOVANNA; DAL PIAZ, Fabrizio; Antonio, Vassallo; Riccio, Raffaele; Bruno, Ines; Bifulco, Giuseppe | |
| Discovery of new molecular entities able to strongly interfere with Hsp90 C-terminal domain | 1-gen-2018 | Terracciano, Stefania; Russo, Alessandra; Chini, Maria G.; Vaccaro, Maria C.; Potenza, Marianna; Vassallo, Antonio; Riccio, Raffaele; Bifulco, Giuseppe; Bruno, Ines | |
| Discovery That Theonellasterol a Marine Sponge Sterol Is a Highly Selective FXR Antagonist That Protects against Liver Injury in Cholestasis | 1-gen-2012 | Barbara, Renga; Andrea, Mencarelli; Claudio, D'Amore; Sabrina, Cipriani; Maria Valeria, D'Auria; Valentina, Sepe; Chini, MARIA GIOVANNA; Monti, Maria Chiara; Bifulco, Giuseppe; Angela, Zampella; Stefano, Fiorucci | |
| Diterpenoids from Zhumeria majdae roots as potential heat shock protein 90 (HSP90) modulators | 1-gen-2021 | Zadali, R.; Nejad-Ebrahimi, S.; Hadjiakhoondi, A.; Fiengo, L.; D'Ambola, M.; De Vita, S.; Tofighi, Z.; Chini, M. G.; Bifulco, G.; De Tommasi, N. | |
| Down regulation of pro-inflammatory pathways by tanshinone IIA and cryptotanshinone in a non-genetic mouse model of Alzheimer's disease | 1-gen-2018 | Maione, Francesco; Piccolo, Marialuisa; DE VITA, Simona; Chini, Maria Giovanna; Cristiano, Claudia; De Caro, Carmen; Lippiello, Pellegrino; Miniaci, Maria Concetta; Santamaria, Rita; Irace, Carlo; De Feo, Vincenzo; Calignano, Antonio; Mascolo, Nicola; Bifulco, Giuseppe |