Sfoglia per Autore
Inverse Virtual Screening of Antitumor Targets: Pilot Study on a Small Database of Natural Bioactive Compounds
2011 Lauro, Gianluigi; A., Romano; Riccio, Raffaele; Bifulco, Giuseppe
Inverse Virtual Screening allows the discovery of the biological activity of natural compounds
2012 Lauro, Gianluigi; Masullo, Milena; Piacente, Sonia; Riccio, Raffaele; Bifulco, Giuseppe
Discovery and Synthesis of Namalide Reveals a New Anabaenopeptin Scaffold and Peptidase Inhibitor
2012 Cheruku, Pradeep; Plaza, Alberto; Lauro, Gianluigi; Keffer, Jessica; Lloyd, John R.; Bifulco, Giuseppe; Bewley, Carole A.
Modification in the side chain of solomonsterol A: discovery of cholestan disulfate as a potent pregnane-X-receptor agonist
2012 Valentina, Sepe; Raffaella, Ummarino; Maria Valeria, Dauria; Lauro, Gianluigi; Bifulco, Giuseppe; Claudio, D'Amore; Barbara, Renga; Stefano, Fiorucci; Angela, Zampella
Plakilactones from the marine sponge Plakinastrella mamillaris. Discovery of a new class of marine ligands of peroxisome proliferator-activated receptor γ
2012 Festa, Carmen; Lauro, Gianluigi; De Marino, Simon; D'Auria, Maria Valeria; Monti, Maria Chiara; Casapullo, Agostino; D'Amore, Claudio; Renga, Barbara; Mencarelli, Andrea; Petek, Sylvain; Bifulco, Giuseppe; Fiorucci, Stefano; Zampella, Angela
Oxygenated polyketides from plakinastrella mamillaris as a new chemotype of PXR agonists
2013 Festa, Carmen; D'Amore, Claudio; Renga, Barbara; Lauro, Gianluigi; De Marino, Simona; D'Auria, Maria Valeria; Bifulco, Giuseppe; Zampella, Angela; Fiorucci, Stefano
Chemical proteomics reveals HSP70 1A as a target for the anticancer diterpene oridonin in Jurkat cells
2013 DAL PIAZ, Fabrizio; Cotugno, Roberta; Lepore, Laura; Vassallo, Antonio; Malafronte, Nicola; Lauro, Gianluigi; Bifulco, Giuseppe; Belisario, MARIA ANTONIETTA; DE TOMMASI, Nunziatina
New techniques of molecular modelling and structural chemistry for the development of bioactive compounds
2013 Lauro, Gianluigi
Reranking docking poses using molecular simulations and approximate free energy methods
2014 Lauro, G.; Ferruz, N.; Fulle, S.; Harvey, M. J.; Finn, P. W.; De Fabritiis, G.
Structural Evidence ofN6-Isopentenyladenosine As a New Ligand of Farnesyl Pyrophosphate Synthase
2014 Scrima, Mario; Lauro, Gianluigi; Grimaldi, Manuela; Sara Di, Marino; Tosco, Alessandra; Picardi, Paola; Gazzerro, Patrizia; Riccio, Raffaele; Ettore, Novellino; Bifulco, Maurizio; Bifulco, Giuseppe; D'Ursi, Anna Maria
New Steroids with a Rearranged Skeleton as (h)P300 Inhibitors from the SpongeTheonella swinhoei
2014 Jun, Gong; Peng, Sun; Nan, Jiang; Riccio, Raffaele; Lauro, Gianluigi; Bifulco, Giuseppe; Tie Jun, Li; William H., Gerwick; Wen, Zhang
Hyalachelins A–C, Unusual Siderophores Isolated from the Terrestrial MyxobacteriumHyalangium minutum
2014 Suvd, Nadmid; Alberto, Plaza; Lauro, Gianluigi; Ronald, Garcia; Bifulco, Giuseppe; Rolf, Müller
Exploration of the dihydropyrimidine scaffold for the development of new potential anti-inflammatory agents blocking prostaglandin E2 synthase-1 enzyme (mPGES-1)
2014 Lauro, Gianluigi; Strocchia, Maria; Terracciano, Stefania; Bruno, Ines; Katrin, Fischer; Carlo, Pergola; Oliver, Werz; Riccio, Raffaele; Bifulco, Giuseppe
Pharmacological evaluation and docking studies of α,β-unsaturated carbonyl based synthetic compounds as inhibitors of secretory phospholipase A2, cyclooxygenases, lipoxygenase and proinflammatory cytokines
2014 Syed Nasir Abbas, Bukhari; Lauro, Gianluigi; Ibrahim, Jantan; Bifulco, Giuseppe; Muhammad Wahab, Amjad
Inhibition of Microsomal Prostaglandin E2 Synthase 1: focused design of new anti-inflammatory and anti-cancer drugs
2015 Foglia, Antonio; Terracciano, Stefania; Lauro, Gianluigi; Saturnino, Carmela; Bruno, Ines; Riccio, Raffaele; Bifulco, Giuseppe
9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain
2015 Picaud, Sarah; Strocchia, Maria; Terracciano, Stefania; Lauro, Gianluigi; Mendez, Jacqui; Daniels, Danette L; Riccio, Raffaele; Bifulco, Giuseppe; Bruno, Ines; Filippakopoulos, Panagis
Giffonins J-P, Highly Hydroxylated Cyclized Diarylheptanoids from the Leaves of Corylus avellana Cultivar "Tonda di Giffoni"
2015 Masullo, Milena; Cantone, Vincenza; Cerulli, Antonietta; Lauro, Gianluigi; Messano, Francesco; Russo, Gian Luigi; Pizza, Cosimo; Bifulco, Giuseppe; Piacente, Sonia
Structural Insights for the Optimization of Dihydropyrimidin-2(1H)-one Based mPGES-1 Inhibitors
2015 Terracciano, Stefania; Lauro, Gianluigi; Strocchia, Maria; Fischer, Katrin; Werz, Oliver; Riccio, Raffaele; Bruno, Ines; Bifulco, Giuseppe
Targeting Microsomal Prostaglanding E2 Synthase 1 for the Development of new potential Anti-Inflammatory Drugs
2015 Foglia, Antonio; Terracciano, Stefania; Lauro, Gianluigi; Saturnino, Carmela; Riccio, Raffaele; Bruno, Ines; Bifulco, Giuseppe
Structure-Based Design of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors using a Virtual Fragment Growing Optimization Scheme
2016 Lauro, Gianluigi; Tortorella, Paolo; Bertamino, Alessia; Ostacolo, Carmine; Koeberle, Andreas; Fischer, Katrin; Bruno, Ines; Terracciano, Stefania; Gomez Monterrey, Isabel Maria; Tauro, Marilena; Loiodice, Fulvio; Novellino, Ettore; Riccio, Raffaele; Werz, Oliver; Campiglia, Pietro; Bifulco, Giuseppe
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Inverse Virtual Screening of Antitumor Targets: Pilot Study on a Small Database of Natural Bioactive Compounds | 1-gen-2011 | Lauro, Gianluigi; A., Romano; Riccio, Raffaele; Bifulco, Giuseppe | |
| Inverse Virtual Screening allows the discovery of the biological activity of natural compounds | 1-gen-2012 | Lauro, Gianluigi; Masullo, Milena; Piacente, Sonia; Riccio, Raffaele; Bifulco, Giuseppe | |
| Discovery and Synthesis of Namalide Reveals a New Anabaenopeptin Scaffold and Peptidase Inhibitor | 1-gen-2012 | Cheruku, Pradeep; Plaza, Alberto; Lauro, Gianluigi; Keffer, Jessica; Lloyd, John R.; Bifulco, Giuseppe; Bewley, Carole A. | |
| Modification in the side chain of solomonsterol A: discovery of cholestan disulfate as a potent pregnane-X-receptor agonist | 1-gen-2012 | Valentina, Sepe; Raffaella, Ummarino; Maria Valeria, Dauria; Lauro, Gianluigi; Bifulco, Giuseppe; Claudio, D'Amore; Barbara, Renga; Stefano, Fiorucci; Angela, Zampella | |
| Plakilactones from the marine sponge Plakinastrella mamillaris. Discovery of a new class of marine ligands of peroxisome proliferator-activated receptor γ | 1-gen-2012 | Festa, Carmen; Lauro, Gianluigi; De Marino, Simon; D'Auria, Maria Valeria; Monti, Maria Chiara; Casapullo, Agostino; D'Amore, Claudio; Renga, Barbara; Mencarelli, Andrea; Petek, Sylvain; Bifulco, Giuseppe; Fiorucci, Stefano; Zampella, Angela | |
| Oxygenated polyketides from plakinastrella mamillaris as a new chemotype of PXR agonists | 1-gen-2013 | Festa, Carmen; D'Amore, Claudio; Renga, Barbara; Lauro, Gianluigi; De Marino, Simona; D'Auria, Maria Valeria; Bifulco, Giuseppe; Zampella, Angela; Fiorucci, Stefano | |
| Chemical proteomics reveals HSP70 1A as a target for the anticancer diterpene oridonin in Jurkat cells | 1-gen-2013 | DAL PIAZ, Fabrizio; Cotugno, Roberta; Lepore, Laura; Vassallo, Antonio; Malafronte, Nicola; Lauro, Gianluigi; Bifulco, Giuseppe; Belisario, MARIA ANTONIETTA; DE TOMMASI, Nunziatina | |
| New techniques of molecular modelling and structural chemistry for the development of bioactive compounds | 14-mag-2013 | Lauro, Gianluigi | |
| Reranking docking poses using molecular simulations and approximate free energy methods | 1-gen-2014 | Lauro, G.; Ferruz, N.; Fulle, S.; Harvey, M. J.; Finn, P. W.; De Fabritiis, G. | |
| Structural Evidence ofN6-Isopentenyladenosine As a New Ligand of Farnesyl Pyrophosphate Synthase | 1-gen-2014 | Scrima, Mario; Lauro, Gianluigi; Grimaldi, Manuela; Sara Di, Marino; Tosco, Alessandra; Picardi, Paola; Gazzerro, Patrizia; Riccio, Raffaele; Ettore, Novellino; Bifulco, Maurizio; Bifulco, Giuseppe; D'Ursi, Anna Maria | |
| New Steroids with a Rearranged Skeleton as (h)P300 Inhibitors from the SpongeTheonella swinhoei | 1-gen-2014 | Jun, Gong; Peng, Sun; Nan, Jiang; Riccio, Raffaele; Lauro, Gianluigi; Bifulco, Giuseppe; Tie Jun, Li; William H., Gerwick; Wen, Zhang | |
| Hyalachelins A–C, Unusual Siderophores Isolated from the Terrestrial MyxobacteriumHyalangium minutum | 1-gen-2014 | Suvd, Nadmid; Alberto, Plaza; Lauro, Gianluigi; Ronald, Garcia; Bifulco, Giuseppe; Rolf, Müller | |
| Exploration of the dihydropyrimidine scaffold for the development of new potential anti-inflammatory agents blocking prostaglandin E2 synthase-1 enzyme (mPGES-1) | 1-gen-2014 | Lauro, Gianluigi; Strocchia, Maria; Terracciano, Stefania; Bruno, Ines; Katrin, Fischer; Carlo, Pergola; Oliver, Werz; Riccio, Raffaele; Bifulco, Giuseppe | |
| Pharmacological evaluation and docking studies of α,β-unsaturated carbonyl based synthetic compounds as inhibitors of secretory phospholipase A2, cyclooxygenases, lipoxygenase and proinflammatory cytokines | 1-gen-2014 | Syed Nasir Abbas, Bukhari; Lauro, Gianluigi; Ibrahim, Jantan; Bifulco, Giuseppe; Muhammad Wahab, Amjad | |
| Inhibition of Microsomal Prostaglandin E2 Synthase 1: focused design of new anti-inflammatory and anti-cancer drugs | 1-gen-2015 | Foglia, Antonio; Terracciano, Stefania; Lauro, Gianluigi; Saturnino, Carmela; Bruno, Ines; Riccio, Raffaele; Bifulco, Giuseppe | |
| 9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain | 1-gen-2015 | Picaud, Sarah; Strocchia, Maria; Terracciano, Stefania; Lauro, Gianluigi; Mendez, Jacqui; Daniels, Danette L; Riccio, Raffaele; Bifulco, Giuseppe; Bruno, Ines; Filippakopoulos, Panagis | |
| Giffonins J-P, Highly Hydroxylated Cyclized Diarylheptanoids from the Leaves of Corylus avellana Cultivar "Tonda di Giffoni" | 1-gen-2015 | Masullo, Milena; Cantone, Vincenza; Cerulli, Antonietta; Lauro, Gianluigi; Messano, Francesco; Russo, Gian Luigi; Pizza, Cosimo; Bifulco, Giuseppe; Piacente, Sonia | |
| Structural Insights for the Optimization of Dihydropyrimidin-2(1H)-one Based mPGES-1 Inhibitors | 1-gen-2015 | Terracciano, Stefania; Lauro, Gianluigi; Strocchia, Maria; Fischer, Katrin; Werz, Oliver; Riccio, Raffaele; Bruno, Ines; Bifulco, Giuseppe | |
| Targeting Microsomal Prostaglanding E2 Synthase 1 for the Development of new potential Anti-Inflammatory Drugs | 1-gen-2015 | Foglia, Antonio; Terracciano, Stefania; Lauro, Gianluigi; Saturnino, Carmela; Riccio, Raffaele; Bruno, Ines; Bifulco, Giuseppe | |
| Structure-Based Design of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1) Inhibitors using a Virtual Fragment Growing Optimization Scheme | 1-gen-2016 | Lauro, Gianluigi; Tortorella, Paolo; Bertamino, Alessia; Ostacolo, Carmine; Koeberle, Andreas; Fischer, Katrin; Bruno, Ines; Terracciano, Stefania; Gomez Monterrey, Isabel Maria; Tauro, Marilena; Loiodice, Fulvio; Novellino, Ettore; Riccio, Raffaele; Werz, Oliver; Campiglia, Pietro; Bifulco, Giuseppe |
Legenda icone
- file ad accesso aperto
- file disponibili sulla rete interna
- file disponibili agli utenti autorizzati
- file disponibili solo agli amministratori
- file sotto embargo
- nessun file disponibile