GAZZILLO, ERICA
GAZZILLO, ERICA
Dipartimento di Farmacia/DIFARMA
6-Methylquinazolin-4(3H)-one Based Compounds as BRD9 Epigenetic Reader Binders: A Rational Combination of in silico Studies and Chemical Synthesis
2022 Colarusso, E; Gazzillo, E; Boccia, E; Giordano, A; Chini, Mg; Bifulco, G; Lauro, G
A Comprehensive In Vitro Characterization of a New Class of Indole-Based Compounds Developed as Selective Haspin Inhibitors
2024 Vestuto, Vincenzo; Ciaglia, Tania; Musella, Simona; Di Sarno, Veronica; Smaldone, Gerardina; Di Matteo, Francesca; Scala, Maria Carmina; Napolitano, Valeria; Miranda, Maria Rosaria; Amodio, Giuseppina; Novi, Sara; Pepe, Giacomo; Basilicata, Manuela Giovanna; Gazzillo, Erica; Pace, Simona; Gomez-Monterrey, Isabel M.; Sala, Marina; Bifulco, Giuseppe; Tecce, Mario Felice; Campiglia, Pietro; Ostacolo, Carmine; Lauro, Gianluigi; Manfra, Michele; Bertamino, Alessia
Exploring the Anticancer Potential of Premna resinosa (Hochst.) Leaf Surface Extract: Discovering New Diterpenes as Heat Shock Protein 70 (Hsp70) Binding Agents
2023 Parisi, V.; Donadio, G.; Bellone, M. L.; Belaabed, S.; Bader, A.; Bisio, A.; Iobbi, V.; Gazzillo, E.; Chini, M. G.; Bifulco, G.; Faraone, I.; Vassallo, A.
Exploring the chemical space of functionalized [1,2,4]triazolo[4,3-a]quinoxaline-based compounds targeting the bromodomain of BRD9
2023 Gazzillo, Erica; Pierri, Martina; Colarusso, Ester; Chini, Maria Giovanna; Ferraro, Maria Grazia; Piccolo, Marialuisa; Irace, Carlo; Bruno, Ines; Bifulco, Giuseppe; Terracciano, Stefania; Lauro, Gianluigi
Fatty Acid Synthase as Interacting Anticancer Target of the Terpenoid Myrianthic Acid Disclosed by MS-Based Proteomics Approaches
2024 Capuano, A.; D'Urso, G.; Gazzillo, E.; Lauro, G.; Chini, M. G.; D'Auria, M. V.; Ferraro, M. G.; Iazzetti, F.; Irace, C.; Bifulco, G.; Casapullo, A.
Identification of 2,4,5-trisubstituted-2,4-dihydro-3H-1,2,4-triazol-3-one-based small molecules as selective BRD9 binders
2023 Colarusso, Ester; Ceccacci, Sara; Monti, Maria Chiara; Gazzillo, Erica; Giordano, Assunta; Chini, Maria Giovanna; Ferraro, Maria Grazia; Piccolo, Marialuisa; Ruggiero, Dafne; Irace, Carlo; Terracciano, Stefania; Bruno, Ines; Bifulco, Giuseppe; Lauro, Gianluigi
Identification of Novel Bromodomain-Containing Protein 4 (BRD4) Binders through 3D Pharmacophore-Based Repositioning Screening Campaign
2024 Colarusso, E.; Gazzillo, E.; Boccia, E.; Terracciano, S.; Bruno, I.; Bifulco, G.; Chini, M. G.; Lauro, G.
In Silico Design, Chemical Synthesis, Biophysical and in Vitro Evaluation for the Identification of 1-Ethyl-1H-Pyrazolo[3,4-b]Pyridine-Based BRD9 Binders
2024 Colarusso, E.; Gazzillo, E.; Pierri, M.; Ruggiero, D.; Chini, M. G.; Bruno, I.; Bifulco, G.; Terracciano, S.; Lauro, G.
Introducing structure-based three-dimensional pharmacophore models for accelerating the discovery of selective BRD9 binders
2022 Pierri, M.; Gazzillo, E.; Chini, M. G.; Ferraro, M. G.; Piccolo, M.; Maione, F.; Irace, C.; Bifulco, G.; Bruno, I.; Terracciano, S.; Lauro, G.
Prodrug Approach to Exploit (S) Alanine as Arginine Mimic Moiety in the Development of Protein Arginine Methyltransferase 4 Inhibitors
2024 Milite, Ciro; Sarno, Giuliana; Pacilio, Ida; Cianciulli, Agostino; Viviano, Monica; Iannelli, Giulia; Gazzillo, Erica; Feoli, Alessandra; Cipriano, Alessandra; Chini, Maria Giovanna; Castellano, Sabrina; Bifulco, Giuseppe; Sbardella, Gianluca
Repositioning of Quinazolinedione-Based Compounds on Soluble Epoxide Hydrolase (sEH) through 3D Structure-Based Pharmacophore Model-Driven Investigation
2022 Gazzillo, Erica; Terracciano, Stefania; Ruggiero, Dafne; Potenza, Marianna; Chini, Maria Giovanna; Lauro, Gianluigi; Fischer, Katrin; Hofstetter, Robert Klaus; Giordano, Assunta; Werz, Oliver; Bruno, Ines; Bifulco, Giuseppe
Repositioning of Small Molecules through the Inverse Virtual Screening in silico Tool: Case of Benzothiazole-Based Inhibitors of Soluble Epoxide Hydrolase (sEH)
2024 Gazzillo, E.; Colarusso, E.; Giordano, A.; Chini, M. G.; Potenza, M.; Hofstetter, R. K.; Iorizzi, M.; Werz, O.; Lauro, G.; Bifulco, G.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 6-Methylquinazolin-4(3H)-one Based Compounds as BRD9 Epigenetic Reader Binders: A Rational Combination of in silico Studies and Chemical Synthesis | 1-gen-2022 | Colarusso, E; Gazzillo, E; Boccia, E; Giordano, A; Chini, Mg; Bifulco, G; Lauro, G | |
| A Comprehensive In Vitro Characterization of a New Class of Indole-Based Compounds Developed as Selective Haspin Inhibitors | 1-gen-2024 | Vestuto, Vincenzo; Ciaglia, Tania; Musella, Simona; Di Sarno, Veronica; Smaldone, Gerardina; Di Matteo, Francesca; Scala, Maria Carmina; Napolitano, Valeria; Miranda, Maria Rosaria; Amodio, Giuseppina; Novi, Sara; Pepe, Giacomo; Basilicata, Manuela Giovanna; Gazzillo, Erica; Pace, Simona; Gomez-Monterrey, Isabel M.; Sala, Marina; Bifulco, Giuseppe; Tecce, Mario Felice; Campiglia, Pietro; Ostacolo, Carmine; Lauro, Gianluigi; Manfra, Michele; Bertamino, Alessia | |
| Exploring the Anticancer Potential of Premna resinosa (Hochst.) Leaf Surface Extract: Discovering New Diterpenes as Heat Shock Protein 70 (Hsp70) Binding Agents | 1-gen-2023 | Parisi, V.; Donadio, G.; Bellone, M. L.; Belaabed, S.; Bader, A.; Bisio, A.; Iobbi, V.; Gazzillo, E.; Chini, M. G.; Bifulco, G.; Faraone, I.; Vassallo, A. | |
| Exploring the chemical space of functionalized [1,2,4]triazolo[4,3-a]quinoxaline-based compounds targeting the bromodomain of BRD9 | 1-gen-2023 | Gazzillo, Erica; Pierri, Martina; Colarusso, Ester; Chini, Maria Giovanna; Ferraro, Maria Grazia; Piccolo, Marialuisa; Irace, Carlo; Bruno, Ines; Bifulco, Giuseppe; Terracciano, Stefania; Lauro, Gianluigi | |
| Fatty Acid Synthase as Interacting Anticancer Target of the Terpenoid Myrianthic Acid Disclosed by MS-Based Proteomics Approaches | 1-gen-2024 | Capuano, A.; D'Urso, G.; Gazzillo, E.; Lauro, G.; Chini, M. G.; D'Auria, M. V.; Ferraro, M. G.; Iazzetti, F.; Irace, C.; Bifulco, G.; Casapullo, A. | |
| Identification of 2,4,5-trisubstituted-2,4-dihydro-3H-1,2,4-triazol-3-one-based small molecules as selective BRD9 binders | 1-gen-2023 | Colarusso, Ester; Ceccacci, Sara; Monti, Maria Chiara; Gazzillo, Erica; Giordano, Assunta; Chini, Maria Giovanna; Ferraro, Maria Grazia; Piccolo, Marialuisa; Ruggiero, Dafne; Irace, Carlo; Terracciano, Stefania; Bruno, Ines; Bifulco, Giuseppe; Lauro, Gianluigi | |
| Identification of Novel Bromodomain-Containing Protein 4 (BRD4) Binders through 3D Pharmacophore-Based Repositioning Screening Campaign | 1-gen-2024 | Colarusso, E.; Gazzillo, E.; Boccia, E.; Terracciano, S.; Bruno, I.; Bifulco, G.; Chini, M. G.; Lauro, G. | |
| In Silico Design, Chemical Synthesis, Biophysical and in Vitro Evaluation for the Identification of 1-Ethyl-1H-Pyrazolo[3,4-b]Pyridine-Based BRD9 Binders | 1-gen-2024 | Colarusso, E.; Gazzillo, E.; Pierri, M.; Ruggiero, D.; Chini, M. G.; Bruno, I.; Bifulco, G.; Terracciano, S.; Lauro, G. | |
| Introducing structure-based three-dimensional pharmacophore models for accelerating the discovery of selective BRD9 binders | 1-gen-2022 | Pierri, M.; Gazzillo, E.; Chini, M. G.; Ferraro, M. G.; Piccolo, M.; Maione, F.; Irace, C.; Bifulco, G.; Bruno, I.; Terracciano, S.; Lauro, G. | |
| Prodrug Approach to Exploit (S) Alanine as Arginine Mimic Moiety in the Development of Protein Arginine Methyltransferase 4 Inhibitors | 1-gen-2024 | Milite, Ciro; Sarno, Giuliana; Pacilio, Ida; Cianciulli, Agostino; Viviano, Monica; Iannelli, Giulia; Gazzillo, Erica; Feoli, Alessandra; Cipriano, Alessandra; Chini, Maria Giovanna; Castellano, Sabrina; Bifulco, Giuseppe; Sbardella, Gianluca | |
| Repositioning of Quinazolinedione-Based Compounds on Soluble Epoxide Hydrolase (sEH) through 3D Structure-Based Pharmacophore Model-Driven Investigation | 1-gen-2022 | Gazzillo, Erica; Terracciano, Stefania; Ruggiero, Dafne; Potenza, Marianna; Chini, Maria Giovanna; Lauro, Gianluigi; Fischer, Katrin; Hofstetter, Robert Klaus; Giordano, Assunta; Werz, Oliver; Bruno, Ines; Bifulco, Giuseppe | |
| Repositioning of Small Molecules through the Inverse Virtual Screening in silico Tool: Case of Benzothiazole-Based Inhibitors of Soluble Epoxide Hydrolase (sEH) | 1-gen-2024 | Gazzillo, E.; Colarusso, E.; Giordano, A.; Chini, M. G.; Potenza, M.; Hofstetter, R. K.; Iorizzi, M.; Werz, O.; Lauro, G.; Bifulco, G. |