A device for inducing cell. permeability in a portion of tissue by opto-poration comprising' an elongate body (2) along an axis H provided with a first tapered cutting end (3) shaped to pierce the skin and/or the underlying tissue and be inserted into a portion (F) of tissue; the elongated body (2) is of the tubular type and defines an internal cavity (4) defined by a side wall (5) and is provided with at least one opening (6) made on the side wall (5) and arranged at a predetermined distance from the tapered cutting end (3). The elongated body houses in the cavity (4) a waveguide (7) configured to convey a laser beam fed in input to the waveguide and a side™ emitting deflection device (8) adapted to vary the direction of propagation of the laser beam so that the laser beam exits from the opening (6) propagating transversely to the axis (H) so as to impinge the portion of tissue (F) arranged around the elongated body (2)
Device for inducing cell permeability in a portion of tissue by opto-poration
Martino Giaquinto;
2022-01-01
Abstract
A device for inducing cell. permeability in a portion of tissue by opto-poration comprising' an elongate body (2) along an axis H provided with a first tapered cutting end (3) shaped to pierce the skin and/or the underlying tissue and be inserted into a portion (F) of tissue; the elongated body (2) is of the tubular type and defines an internal cavity (4) defined by a side wall (5) and is provided with at least one opening (6) made on the side wall (5) and arranged at a predetermined distance from the tapered cutting end (3). The elongated body houses in the cavity (4) a waveguide (7) configured to convey a laser beam fed in input to the waveguide and a side™ emitting deflection device (8) adapted to vary the direction of propagation of the laser beam so that the laser beam exits from the opening (6) propagating transversely to the axis (H) so as to impinge the portion of tissue (F) arranged around the elongated body (2)I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.