Sfoglia per Autore
Regulation of USP37 Expression by REST-associated G9a-dependent Histone Methylation
2017-01-01 Dobson, Tara; Hatcher, Rashieda J; Swaminathan, Jyothismathi; Das, Chandra M; Shaik, Shavali; Tao, Rong Hua; Milite, Ciro; Castellano, Sabrina; Taylor, Pete; Sbardella, Gianluca; Gopalakrishnan, Vidya
Design, synthesis and biological evaluation of new selective arginine methyltransferases (PRMTs) Inhibitors
2018-01-01 Milite, C.; Feoli, A.; Rescigno, D.; Clarke, S.; Castellano, S.; Sbardella, G.
Expanding the quinazoline ring to 3H-benzo[e][1,4]diazepine: development of new and selective G9a inhibitors
2018-01-01 Milite, C.; Feoli, A.; Rescigno, Donatella; Pisapia, Vincenzo; Cosconati, S.; Castellano, S.; Sbardella, G.
4-Substituted Benzenesulfonamides Incorporating Bi/Tricyclic Moieties Act as Potent and Isoform-Selective Carbonic Anhydrase II/IX Inhibitors
2018-01-01 Salerno, Silvia; Barresi, Elisabetta; Amendola, Giorgio; Berrino, Emanuela; Milite, Ciro; Marini, Anna Maria; DA SETTIMO PASSETTI, Federico; Novellino, Ettore; Supuran, Claudiu T.; Cosconati, Sandro; Taliani, Sabrina
Discovery of a novel chemotype of histone lysine methyltransferase EHMT1/2 (GLP/G9a) inhibitors: rational design, synthesis, biological evaluation and co-crystal structure
2019-01-01 Milite, Ciro; Feoli, Alessandra; Horton, John R; Rescigno, Donatella; Cipriano, Alessandra; Pisapia, Vincenzo; Viviano, Monica; Pepe, Giacomo; Amendola, Giorgio; Novellino, Ettore; Cosconati, Sandro; Cheng, Xiaodong; Castellano, Sabrina; Sbardella, Gianluca
Novel 2-substituted-benzimidazole-6-sulfonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IX and XII and molecular docking studies
2019-01-01 Milite, C.; Amendola, G.; Nocentini, A.; Bua, S.; Cipriano, A.; Barresi, E.; Feoli, A.; Novellino, E.; Da Settimo, F.; Supuran, C. T.; Castellano, S.; Cosconati, S.; Taliani, S.
Reverse transcriptase inhibition potentiates target therapy in BRAF-mutant melanomas: effects on cell proliferation, apoptosis, DNA-damage, ROS induction and mitochondrial membrane depolarization
2020-01-01 Fattore, Luigi; Malpicci, Debora; Milite, Ciro; Castellano, Sabrina; Sbardella, Gianluca; Botti, Gerardo; Ascierto, Paolo Antonio; Mancini, Rita; Ciliberto, Gennaro
Patent evaluation of WO2019209182 (A1) 2019-10-31 (Conjugated Oligoelectrolytes as Antimicrobial Agents)
2020-01-01 Milite, C.
Reverse transcriptase inhibitors promote the remodeling of nuclear architecture and induce autophagy in prostate cancer cells
2020-01-01 Bellisai, Cristina; Sciamanna, Ilaria; Rovella, Paola; Giovannini, Daniela; Baranzini, Mirko; Pugliese, Giusj Monia; Zeya Ansari, Mohammad Salik; Milite, Ciro; Sinibaldi-Vallebona, Paola; Cirilli, Roberto; Sbardella, Gianluca; Pichierri, Pietro; Trisciuoglio, Daniela; Lavia, Patrizia; Serafino, Annalucia; Spadafora, Corrado
Lysine methyltransferase inhibitors: where we are now.
2022-01-01 Feoli, Alessandra; Viviano, Monica; Cipriano, Alessandra; Milite, Ciro; Castellano, Sabrina; Sbardella, Gianluca
Microwave-Assisted Aminoalkylation of Phenols via Mustard Carbonate Analogues
2022-01-01 Viviano, M.; Trapasso, G.; Annatelli, M.; Milite, C.; Castellano, S.; Arico, F.
Discovery of benzo[d]imidazole-6-sulfonamides as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain
2022-01-01 Cipriano, Alessandra; Milite, Ciro; Feoli, Alessandra; Viviano, Monica; Pepe, Giacomo; Campiglia, Pietro; Sarno, Giuliana; Picaud, Sarah; Imaide, Satomi; Makukhin, Nikolai; Filippakopoulos, Panagis; Ciulli, Alessio; Castellano, Sabrina; Sbardella, Gianluca
Age-dependent attenuation of spatial memory deficits by the histone acetyltransferase p300/CBP-associated factor (PCAF) in 3xTG Alzheimer's disease mice
2022-01-01 Creighton, Samantha D.; Jardine, Kristen H.; Desimone, Alexa; Zmetana, Megan; Castellano, Sabrina; Milite, Ciro; Sbardella, Gianluca; Winters, Boyer D.
Turning Nonselective Inhibitors of Type I Protein Arginine Methyltransferases into Potent and Selective Inhibitors of Protein Arginine Methyltransferase 4 through a Deconstruction-Reconstruction and Fragment-Growing Approach
2022-01-01 Iannelli, Giulia; Milite, Ciro; Marechal, Nils; Cura, Vincent; Bonnefond, Luc; Troffer-Charlier, Nathalie; Feoli, Alessandra; Rescigno, Donatella; Wang, Yalong; Cipriano, Alessandra; Viviano, Monica; Bedford, Mark T; Cavarelli, Jean; Castellano, Sabrina; Sbardella, Gianluca
NADPH Oxidases: From Molecular Mechanisms to Current Inhibitors
2023-01-01 Cipriano, Alessandra; Viviano, Monica; Feoli, Alessandra; Milite, Ciro; Sarno, Giuliana; Castellano, Sabrina; Sbardella, Gianluca
Identification of a Protein Arginine Methyltransferase 7 (PRMT7)/Protein Arginine Methyltransferase 9 (PRMT9) Inhibitor
2023-01-01 Feoli, Alessandra; Iannelli, Giulia; Cipriano, Alessandra; Milite, Ciro; Shen, Lei; Wang, Zhihao; Hadjikyriacou, Andrea; Lowe, Troy L; Safaeipour, Cyrus; Viviano, Monica; Sarno, Giuliana; Morretta, Elva; Monti, Maria Chiara; Yang, Yanzhong; Clarke, Steven G; Cosconati, Sandro; Castellano, Sabrina; Sbardella, Gianluca
Successes and challenges in the development of BD1-selective BET inhibitors: a patent review
2024-01-01 Viviano, Monica; Cipriano, Alessandra; Fabbrizi, Emanuele; Feoli, Alessandra; Castellano, Sabrina; Sbardella, Gianluca; Mai, Antonello; Milite, Ciro; Rotili, Dante
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Regulation of USP37 Expression by REST-associated G9a-dependent Histone Methylation | 1-gen-2017 | Dobson, Tara; Hatcher, Rashieda J; Swaminathan, Jyothismathi; Das, Chandra M; Shaik, Shavali; Tao, Rong Hua; Milite, Ciro; Castellano, Sabrina; Taylor, Pete; Sbardella, Gianluca; Gopalakrishnan, Vidya | |
| Design, synthesis and biological evaluation of new selective arginine methyltransferases (PRMTs) Inhibitors | 1-gen-2018 | Milite, C.; Feoli, A.; Rescigno, D.; Clarke, S.; Castellano, S.; Sbardella, G. | |
| Expanding the quinazoline ring to 3H-benzo[e][1,4]diazepine: development of new and selective G9a inhibitors | 1-gen-2018 | Milite, C.; Feoli, A.; Rescigno, Donatella; Pisapia, Vincenzo; Cosconati, S.; Castellano, S.; Sbardella, G. | |
| 4-Substituted Benzenesulfonamides Incorporating Bi/Tricyclic Moieties Act as Potent and Isoform-Selective Carbonic Anhydrase II/IX Inhibitors | 1-gen-2018 | Salerno, Silvia; Barresi, Elisabetta; Amendola, Giorgio; Berrino, Emanuela; Milite, Ciro; Marini, Anna Maria; DA SETTIMO PASSETTI, Federico; Novellino, Ettore; Supuran, Claudiu T.; Cosconati, Sandro; Taliani, Sabrina | |
| Discovery of a novel chemotype of histone lysine methyltransferase EHMT1/2 (GLP/G9a) inhibitors: rational design, synthesis, biological evaluation and co-crystal structure | 1-gen-2019 | Milite, Ciro; Feoli, Alessandra; Horton, John R; Rescigno, Donatella; Cipriano, Alessandra; Pisapia, Vincenzo; Viviano, Monica; Pepe, Giacomo; Amendola, Giorgio; Novellino, Ettore; Cosconati, Sandro; Cheng, Xiaodong; Castellano, Sabrina; Sbardella, Gianluca | |
| Novel 2-substituted-benzimidazole-6-sulfonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IX and XII and molecular docking studies | 1-gen-2019 | Milite, C.; Amendola, G.; Nocentini, A.; Bua, S.; Cipriano, A.; Barresi, E.; Feoli, A.; Novellino, E.; Da Settimo, F.; Supuran, C. T.; Castellano, S.; Cosconati, S.; Taliani, S. | |
| Reverse transcriptase inhibition potentiates target therapy in BRAF-mutant melanomas: effects on cell proliferation, apoptosis, DNA-damage, ROS induction and mitochondrial membrane depolarization | 1-gen-2020 | Fattore, Luigi; Malpicci, Debora; Milite, Ciro; Castellano, Sabrina; Sbardella, Gianluca; Botti, Gerardo; Ascierto, Paolo Antonio; Mancini, Rita; Ciliberto, Gennaro | |
| Patent evaluation of WO2019209182 (A1) 2019-10-31 (Conjugated Oligoelectrolytes as Antimicrobial Agents) | 1-gen-2020 | Milite, C. | |
| Reverse transcriptase inhibitors promote the remodeling of nuclear architecture and induce autophagy in prostate cancer cells | 1-gen-2020 | Bellisai, Cristina; Sciamanna, Ilaria; Rovella, Paola; Giovannini, Daniela; Baranzini, Mirko; Pugliese, Giusj Monia; Zeya Ansari, Mohammad Salik; Milite, Ciro; Sinibaldi-Vallebona, Paola; Cirilli, Roberto; Sbardella, Gianluca; Pichierri, Pietro; Trisciuoglio, Daniela; Lavia, Patrizia; Serafino, Annalucia; Spadafora, Corrado | |
| Lysine methyltransferase inhibitors: where we are now. | 1-gen-2022 | Feoli, Alessandra; Viviano, Monica; Cipriano, Alessandra; Milite, Ciro; Castellano, Sabrina; Sbardella, Gianluca | |
| Microwave-Assisted Aminoalkylation of Phenols via Mustard Carbonate Analogues | 1-gen-2022 | Viviano, M.; Trapasso, G.; Annatelli, M.; Milite, C.; Castellano, S.; Arico, F. | |
| Discovery of benzo[d]imidazole-6-sulfonamides as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain | 1-gen-2022 | Cipriano, Alessandra; Milite, Ciro; Feoli, Alessandra; Viviano, Monica; Pepe, Giacomo; Campiglia, Pietro; Sarno, Giuliana; Picaud, Sarah; Imaide, Satomi; Makukhin, Nikolai; Filippakopoulos, Panagis; Ciulli, Alessio; Castellano, Sabrina; Sbardella, Gianluca | |
| Age-dependent attenuation of spatial memory deficits by the histone acetyltransferase p300/CBP-associated factor (PCAF) in 3xTG Alzheimer's disease mice | 1-gen-2022 | Creighton, Samantha D.; Jardine, Kristen H.; Desimone, Alexa; Zmetana, Megan; Castellano, Sabrina; Milite, Ciro; Sbardella, Gianluca; Winters, Boyer D. | |
| Turning Nonselective Inhibitors of Type I Protein Arginine Methyltransferases into Potent and Selective Inhibitors of Protein Arginine Methyltransferase 4 through a Deconstruction-Reconstruction and Fragment-Growing Approach | 1-gen-2022 | Iannelli, Giulia; Milite, Ciro; Marechal, Nils; Cura, Vincent; Bonnefond, Luc; Troffer-Charlier, Nathalie; Feoli, Alessandra; Rescigno, Donatella; Wang, Yalong; Cipriano, Alessandra; Viviano, Monica; Bedford, Mark T; Cavarelli, Jean; Castellano, Sabrina; Sbardella, Gianluca | |
| NADPH Oxidases: From Molecular Mechanisms to Current Inhibitors | 1-gen-2023 | Cipriano, Alessandra; Viviano, Monica; Feoli, Alessandra; Milite, Ciro; Sarno, Giuliana; Castellano, Sabrina; Sbardella, Gianluca | |
| Identification of a Protein Arginine Methyltransferase 7 (PRMT7)/Protein Arginine Methyltransferase 9 (PRMT9) Inhibitor | 1-gen-2023 | Feoli, Alessandra; Iannelli, Giulia; Cipriano, Alessandra; Milite, Ciro; Shen, Lei; Wang, Zhihao; Hadjikyriacou, Andrea; Lowe, Troy L; Safaeipour, Cyrus; Viviano, Monica; Sarno, Giuliana; Morretta, Elva; Monti, Maria Chiara; Yang, Yanzhong; Clarke, Steven G; Cosconati, Sandro; Castellano, Sabrina; Sbardella, Gianluca | |
| Successes and challenges in the development of BD1-selective BET inhibitors: a patent review | 1-gen-2024 | Viviano, Monica; Cipriano, Alessandra; Fabbrizi, Emanuele; Feoli, Alessandra; Castellano, Sabrina; Sbardella, Gianluca; Mai, Antonello; Milite, Ciro; Rotili, Dante |
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