LAURO, GIANLUIGI
LAURO, GIANLUIGI
Dipartimento di Farmacia/DIFARMA
6-Methylquinazolin-4(3H)-one Based Compounds as BRD9 Epigenetic Reader Binders: A Rational Combination of in silico Studies and Chemical Synthesis
2022-01-01 Colarusso, E; Gazzillo, E; Boccia, E; Giordano, A; Chini, Mg; Bifulco, G; Lauro, G
9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain
2015-01-01 Picaud, Sarah; Strocchia, Maria; Terracciano, Stefania; Lauro, Gianluigi; Mendez, Jacqui; Daniels, Danette L; Riccio, Raffaele; Bifulco, Giuseppe; Bruno, Ines; Filippakopoulos, Panagis
A Combinatorial Virtual Screening Approach Driving the Synthesis of 2,4-Thiazolidinedione-Based Molecules as New Dual mPGES-1/5-LO Inhibitors
2020-01-01 Lauro, G.; Terracciano, S.; Cantone, V.; Ruggiero, D.; Fischer, K.; Pace, S.; Werz, O.; Bruno, I.; Bifulco, G.
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
2020-01-01 De Vita, S.; Chini, M. G.; Lauro, G.; Bifulco, G.
Addressing the Target Identification and Accelerating the Repositioning of Anti-Inflammatory/Anti-Cancer Organic Compounds by Computational Approaches
2021-01-01 Chini, M. G.; Lauro, G.; Bifulco, G.
Anti-inflammatory trends of new benzimidazole derivatives
2016-01-01 Bukhari, Syed Nasir Abbas; Lauro, Gianluigi; Jantan, Ibrahim; Chee, Chin Fei; Amjad, Muhammad Wahab; Bifulco, Giuseppe; Sher, Hassan; Abdullah, Iskandar; Rahman, Noorsaadah Abd
Biological Profile of Two Gentiana lutea L. Metabolites Using Computational Approaches and In Vitro Tests
2021-01-01 DE VITA, Simona; Giovanna Chini, Maria; Saviano, Gabriella; Finamore, Claudia; Festa, Carmen; Lauro, Gianluigi; De Marino, Simona; Russo, Roberto; Avagliano, Carmen; Casapullo, Agostino; Calignano, Antonio; Bifulco, Giuseppe; Iorizzi, Maria
Bissubvilides A and B, Cembrane-capnosane heterodimers from the soft coral sarcophyton subviride
2016-01-01 Sun, Peng; Yu, Qing; Li, Jiao; Riccio, Raffaele; Lauro, Gianluigi; Bifulco, Giuseppe; Kurtán, Tibor; Mándi, Attila; Tang, Hua; Li, Tie Jun; Zhuang, Chun Lin; Gerwick, William H.; Zhang, Wen
Chemical proteomics reveals HSP70 1A as a target for the anticancer diterpene oridonin in Jurkat cells
2013-01-01 DAL PIAZ, Fabrizio; Cotugno, Roberta; Lepore, Laura; Vassallo, Antonio; Malafronte, Nicola; Lauro, Gianluigi; Bifulco, Giuseppe; Belisario, MARIA ANTONIETTA; DE TOMMASI, Nunziatina
Chemistry and Selective Tumor Cell Growth Inhibitory Activity of Polyketides from the South China Sea Sponge Plakortis sp
2017-01-01 Li, Jiao; Li, Cui; Riccio, Raffaele; Lauro, Gianluigi; Bifulco, Giuseppe; Li, Tie Jun; Tang, Hua; Zhuang, Chun Lin; Ma, Hao; Sun, Peng; Zhang, Wen
Corylus avellana: A Source of Diarylheptanoids With α-Glucosidase Inhibitory Activity Evaluated by in vitro and in silico Studies
2022-01-01 Masullo, M.; Lauro, G.; Cerulli, A.; Bifulco, G.; Piacente, S.
Cyclic Diarylheptanoids from Corylus avellana Green Leafy Covers: Determination of Their Absolute Configurations and Evaluation of Their Antioxidant and Antimicrobial Activities
2017-01-01 Cerulli, Antonietta; Lauro, Gianluigi; Masullo, Milena; Cantone, Vincenza; Olas, Beata; Kontek, Bogdan; Nazzaro, Filomena; Bifulco, Giuseppe; Piacente, Sonia
DFT/NMR Approach for the Configuration Assignment of Groups of Stereoisomers by the Combination and Comparison of Experimental and Predicted Sets of Data
2020-01-01 Lauro, G.; Das, P.; Riccio, R.; Reddy, D. S.; Bifulco, G.
Discovery and Synthesis of Namalide Reveals a New Anabaenopeptin Scaffold and Peptidase Inhibitor
2012-01-01 Cheruku, Pradeep; Plaza, Alberto; Lauro, Gianluigi; Keffer, Jessica; Lloyd, John R.; Bifulco, Giuseppe; Bewley, Carole A.
Discovery and synthesis of the first selective BAG domain modulator of BAG3 as an attractive candidate for the development of a new class of chemotherapeutics
2018-01-01 Terracciano, Stefania; Lauro, Gianluigi; Russo, Alessandra; Vaccaro, Maria Carmela; Vassallo, Antonio; De Marco, Margot; Ranieri, Bianca; Rosati, Alessandra; Turco, Maria Caterina; Riccio, Raffaele; Bifulco, Giuseppe; Bruno, Ines
Discovery of 3-hydroxy-3-pyrrolin-2-one-based mPGES-1 inhibitors using a multi-step virtual screening protocol
2018-01-01 Lauro, G.; Cantone, V.; Potenza, M.; Fischer, K.; Koeberle, A.; Werz, O.; Riccio, R.; Bifulco, G.
Discovery of a Secalonic Acid Derivative from Aspergillus aculeatus, an Endophyte of Rosa damascena Mill., Triggers Apoptosis in MDA-MB-231 Triple Negative Breast Cancer Cells
2020-01-01 Farooq, S.; Qayum, A.; Nalli, Y.; Lauro, G.; Chini, M. G.; Bifulco, G.; Chaubey, A.; Singh, S. K.; Riyaz-Ul-Hassan, S.; Ali, A.
Discovery of noscapine derivatives as potential β-tubulin inhibitors
2020-01-01 Nemati, F.; Salehi, P.; Bararjanian, M.; Hadian, N.; Mohebbi, M.; Lauro, G.; Ruggiero, D.; Terracciano, S.; Bifulco, G.; Bruno, I.
Elucidating the Relative and Absolute Configuration of Organic Compounds by Quantum Mechanical Approaches
2020-01-01 Lauro, G.; Bifulco, G.
Exploration of the dihydropyrimidine scaffold for the development of new potential anti-inflammatory agents blocking prostaglandin E2 synthase-1 enzyme (mPGES-1)
2014-01-01 Lauro, Gianluigi; Strocchia, Maria; Terracciano, Stefania; Bruno, Ines; Katrin, Fischer; Carlo, Pergola; Oliver, Werz; Riccio, Raffaele; Bifulco, Giuseppe
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 6-Methylquinazolin-4(3H)-one Based Compounds as BRD9 Epigenetic Reader Binders: A Rational Combination of in silico Studies and Chemical Synthesis | 1-gen-2022 | Colarusso, E; Gazzillo, E; Boccia, E; Giordano, A; Chini, Mg; Bifulco, G; Lauro, G | |
| 9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain | 1-gen-2015 | Picaud, Sarah; Strocchia, Maria; Terracciano, Stefania; Lauro, Gianluigi; Mendez, Jacqui; Daniels, Danette L; Riccio, Raffaele; Bifulco, Giuseppe; Bruno, Ines; Filippakopoulos, Panagis | |
| A Combinatorial Virtual Screening Approach Driving the Synthesis of 2,4-Thiazolidinedione-Based Molecules as New Dual mPGES-1/5-LO Inhibitors | 1-gen-2020 | Lauro, G.; Terracciano, S.; Cantone, V.; Ruggiero, D.; Fischer, K.; Pace, S.; Werz, O.; Bruno, I.; Bifulco, G. | |
| Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19) | 1-gen-2020 | De Vita, S.; Chini, M. G.; Lauro, G.; Bifulco, G. | |
| Addressing the Target Identification and Accelerating the Repositioning of Anti-Inflammatory/Anti-Cancer Organic Compounds by Computational Approaches | 1-gen-2021 | Chini, M. G.; Lauro, G.; Bifulco, G. | |
| Anti-inflammatory trends of new benzimidazole derivatives | 1-gen-2016 | Bukhari, Syed Nasir Abbas; Lauro, Gianluigi; Jantan, Ibrahim; Chee, Chin Fei; Amjad, Muhammad Wahab; Bifulco, Giuseppe; Sher, Hassan; Abdullah, Iskandar; Rahman, Noorsaadah Abd | |
| Biological Profile of Two Gentiana lutea L. Metabolites Using Computational Approaches and In Vitro Tests | 1-gen-2021 | DE VITA, Simona; Giovanna Chini, Maria; Saviano, Gabriella; Finamore, Claudia; Festa, Carmen; Lauro, Gianluigi; De Marino, Simona; Russo, Roberto; Avagliano, Carmen; Casapullo, Agostino; Calignano, Antonio; Bifulco, Giuseppe; Iorizzi, Maria | |
| Bissubvilides A and B, Cembrane-capnosane heterodimers from the soft coral sarcophyton subviride | 1-gen-2016 | Sun, Peng; Yu, Qing; Li, Jiao; Riccio, Raffaele; Lauro, Gianluigi; Bifulco, Giuseppe; Kurtán, Tibor; Mándi, Attila; Tang, Hua; Li, Tie Jun; Zhuang, Chun Lin; Gerwick, William H.; Zhang, Wen | |
| Chemical proteomics reveals HSP70 1A as a target for the anticancer diterpene oridonin in Jurkat cells | 1-gen-2013 | DAL PIAZ, Fabrizio; Cotugno, Roberta; Lepore, Laura; Vassallo, Antonio; Malafronte, Nicola; Lauro, Gianluigi; Bifulco, Giuseppe; Belisario, MARIA ANTONIETTA; DE TOMMASI, Nunziatina | |
| Chemistry and Selective Tumor Cell Growth Inhibitory Activity of Polyketides from the South China Sea Sponge Plakortis sp | 1-gen-2017 | Li, Jiao; Li, Cui; Riccio, Raffaele; Lauro, Gianluigi; Bifulco, Giuseppe; Li, Tie Jun; Tang, Hua; Zhuang, Chun Lin; Ma, Hao; Sun, Peng; Zhang, Wen | |
| Corylus avellana: A Source of Diarylheptanoids With α-Glucosidase Inhibitory Activity Evaluated by in vitro and in silico Studies | 1-gen-2022 | Masullo, M.; Lauro, G.; Cerulli, A.; Bifulco, G.; Piacente, S. | |
| Cyclic Diarylheptanoids from Corylus avellana Green Leafy Covers: Determination of Their Absolute Configurations and Evaluation of Their Antioxidant and Antimicrobial Activities | 1-gen-2017 | Cerulli, Antonietta; Lauro, Gianluigi; Masullo, Milena; Cantone, Vincenza; Olas, Beata; Kontek, Bogdan; Nazzaro, Filomena; Bifulco, Giuseppe; Piacente, Sonia | |
| DFT/NMR Approach for the Configuration Assignment of Groups of Stereoisomers by the Combination and Comparison of Experimental and Predicted Sets of Data | 1-gen-2020 | Lauro, G.; Das, P.; Riccio, R.; Reddy, D. S.; Bifulco, G. | |
| Discovery and Synthesis of Namalide Reveals a New Anabaenopeptin Scaffold and Peptidase Inhibitor | 1-gen-2012 | Cheruku, Pradeep; Plaza, Alberto; Lauro, Gianluigi; Keffer, Jessica; Lloyd, John R.; Bifulco, Giuseppe; Bewley, Carole A. | |
| Discovery and synthesis of the first selective BAG domain modulator of BAG3 as an attractive candidate for the development of a new class of chemotherapeutics | 1-gen-2018 | Terracciano, Stefania; Lauro, Gianluigi; Russo, Alessandra; Vaccaro, Maria Carmela; Vassallo, Antonio; De Marco, Margot; Ranieri, Bianca; Rosati, Alessandra; Turco, Maria Caterina; Riccio, Raffaele; Bifulco, Giuseppe; Bruno, Ines | |
| Discovery of 3-hydroxy-3-pyrrolin-2-one-based mPGES-1 inhibitors using a multi-step virtual screening protocol | 1-gen-2018 | Lauro, G.; Cantone, V.; Potenza, M.; Fischer, K.; Koeberle, A.; Werz, O.; Riccio, R.; Bifulco, G. | |
| Discovery of a Secalonic Acid Derivative from Aspergillus aculeatus, an Endophyte of Rosa damascena Mill., Triggers Apoptosis in MDA-MB-231 Triple Negative Breast Cancer Cells | 1-gen-2020 | Farooq, S.; Qayum, A.; Nalli, Y.; Lauro, G.; Chini, M. G.; Bifulco, G.; Chaubey, A.; Singh, S. K.; Riyaz-Ul-Hassan, S.; Ali, A. | |
| Discovery of noscapine derivatives as potential β-tubulin inhibitors | 1-gen-2020 | Nemati, F.; Salehi, P.; Bararjanian, M.; Hadian, N.; Mohebbi, M.; Lauro, G.; Ruggiero, D.; Terracciano, S.; Bifulco, G.; Bruno, I. | |
| Elucidating the Relative and Absolute Configuration of Organic Compounds by Quantum Mechanical Approaches | 1-gen-2020 | Lauro, G.; Bifulco, G. | |
| Exploration of the dihydropyrimidine scaffold for the development of new potential anti-inflammatory agents blocking prostaglandin E2 synthase-1 enzyme (mPGES-1) | 1-gen-2014 | Lauro, Gianluigi; Strocchia, Maria; Terracciano, Stefania; Bruno, Ines; Katrin, Fischer; Carlo, Pergola; Oliver, Werz; Riccio, Raffaele; Bifulco, Giuseppe |