LAURO, Gianluigi
LAURO, Gianluigi
Dipartimento di Farmacia/DIFARMA
2-Substituted 1,5-benzothiazepine-based HDAC inhibitors exert anticancer activities on human solid and acute myeloid leukemia cell lines
2023 De Vita, Simona; Meninno, Sara; Capasso, Lucia; Colarusso, Ester; Chini, Maria Giovanna; Lauro, Gianluigi; Rinaldi, Romolo; De Cicco, Annalisa; Sian, Veronica; Terracciano, Stefania; Nebbioso, Angela; Lattanzi, Alessandra; Bifulco, Giuseppe
5-methyl-2-carboxamidepyrrole-based novel dual mPGES-1/sEH inhibitors as promising anticancer candidates
2025 Colarusso, E.; Lauro, G.; Potenza, M.; Galatello, P.; Garigliota, M. L. D.; Ferraro, M. G.; Piccolo, M.; Chini, M. G.; Irace, C.; Campiglia, P.; Hoffstetter, R. K.; Werz, O.; Ramunno, A.; Bifulco, G.
6-Methylquinazolin-4(3H)-one Based Compounds as BRD9 Epigenetic Reader Binders: A Rational Combination of in silico Studies and Chemical Synthesis
2022 Colarusso, E; Gazzillo, E; Boccia, E; Giordano, A; Chini, Mg; Bifulco, G; Lauro, G
9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain
2015 Picaud, Sarah; Strocchia, Maria; Terracciano, Stefania; Lauro, Gianluigi; Mendez, Jacqui; Daniels, Danette L; Riccio, Raffaele; Bifulco, Giuseppe; Bruno, Ines; Filippakopoulos, Panagis
A Classic Photochemical Approach Inducing an Unexpected Rearrangement: Exploring the Photoreactivity of Pentacyclic Triterpenic Acids
2023 Rogati, F.; Maioli, C.; Lauro, G.; Caprioglio, D.; Imperio, D.; Del Grosso, E.; Botta, B.; Mannina, L.; Bifulco, G.; Ingallina, C.; Minassi, A.
A Combinatorial Virtual Screening Approach Driving the Synthesis of 2,4-Thiazolidinedione-Based Molecules as New Dual mPGES-1/5-LO Inhibitors
2020 Lauro, G.; Terracciano, S.; Cantone, V.; Ruggiero, D.; Fischer, K.; Pace, S.; Werz, O.; Bruno, I.; Bifulco, G.
A Comprehensive In Vitro Characterization of a New Class of Indole-Based Compounds Developed as Selective Haspin Inhibitors
2024 Vestuto, Vincenzo; Ciaglia, Tania; Musella, Simona; Di Sarno, Veronica; Smaldone, Gerardina; Di Matteo, Francesca; Scala, Maria Carmina; Napolitano, Valeria; Miranda, Maria Rosaria; Amodio, Giuseppina; Novi, Sara; Pepe, Giacomo; Basilicata, Manuela Giovanna; Gazzillo, Erica; Pace, Simona; Gomez-Monterrey, Isabel M.; Sala, Marina; Bifulco, Giuseppe; Tecce, Mario Felice; Campiglia, Pietro; Ostacolo, Carmine; Lauro, Gianluigi; Manfra, Michele; Bertamino, Alessia
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
2020 De Vita, S.; Chini, M. G.; Lauro, G.; Bifulco, G.
Addressing the Target Identification and Accelerating the Repositioning of Anti-Inflammatory/Anti-Cancer Organic Compounds by Computational Approaches
2021 Chini, M. G.; Lauro, G.; Bifulco, G.
Anti-inflammatory trends of new benzimidazole derivatives
2016 Bukhari, Syed Nasir Abbas; Lauro, Gianluigi; Jantan, Ibrahim; Chee, Chin Fei; Amjad, Muhammad Wahab; Bifulco, Giuseppe; Sher, Hassan; Abdullah, Iskandar; Rahman, Noorsaadah Abd
Biological Profile of Two Gentiana lutea L. Metabolites Using Computational Approaches and In Vitro Tests
2021 DE VITA, Simona; Giovanna Chini, Maria; Saviano, Gabriella; Finamore, Claudia; Festa, Carmen; Lauro, Gianluigi; De Marino, Simona; Russo, Roberto; Avagliano, Carmen; Casapullo, Agostino; Calignano, Antonio; Bifulco, Giuseppe; Iorizzi, Maria
Bissubvilides A and B, Cembrane-capnosane heterodimers from the soft coral sarcophyton subviride
2016 Sun, Peng; Yu, Qing; Li, Jiao; Riccio, Raffaele; Lauro, Gianluigi; Bifulco, Giuseppe; Kurtán, Tibor; Mándi, Attila; Tang, Hua; Li, Tie Jun; Zhuang, Chun Lin; Gerwick, William H.; Zhang, Wen
Chemical Profiling of Polar Lipids and the Polyphenolic Fraction of Commercial Italian Phaseolus Seeds by UHPLC-HRMS and Biological Evaluation
2024 Samukha, V.; Fantasma, F.; D'Urso, G.; Colarusso, E.; Schettino, A.; Marigliano, N.; Chini, M. G.; Saviano, G.; De Felice, V.; Lauro, G.; Maione, F.; Bifulco, G.; Casapullo, A.; Iorizzi, M.
Chemical proteomics reveals HSP70 1A as a target for the anticancer diterpene oridonin in Jurkat cells
2013 DAL PIAZ, Fabrizio; Cotugno, Roberta; Lepore, Laura; Vassallo, Antonio; Malafronte, Nicola; Lauro, Gianluigi; Bifulco, Giuseppe; Belisario, MARIA ANTONIETTA; DE TOMMASI, Nunziatina
Chemistry and Selective Tumor Cell Growth Inhibitory Activity of Polyketides from the South China Sea Sponge Plakortis sp
2017 Li, Jiao; Li, Cui; Riccio, Raffaele; Lauro, Gianluigi; Bifulco, Giuseppe; Li, Tie Jun; Tang, Hua; Zhuang, Chun Lin; Ma, Hao; Sun, Peng; Zhang, Wen
Chemoproteomics Reveals USP5 (Ubiquitin Carboxyl-Terminal Hydrolase 5) as Promising Target of the Marine Polyketide Gracilioether A
2024 Capuano, A.; D'Urso, G.; Aliberti, M.; Ruggiero, D.; Terracciano, S.; Festa, C.; Tosco, A.; Chini, M. G.; Lauro, G.; Bifulco, G.; Casapullo, A.
Corylus avellana: A Source of Diarylheptanoids With α-Glucosidase Inhibitory Activity Evaluated by in vitro and in silico Studies
2022 Masullo, M.; Lauro, G.; Cerulli, A.; Bifulco, G.; Piacente, S.
Cyclic Diarylheptanoids from Corylus avellana Green Leafy Covers: Determination of Their Absolute Configurations and Evaluation of Their Antioxidant and Antimicrobial Activities
2017 Cerulli, Antonietta; Lauro, Gianluigi; Masullo, Milena; Cantone, Vincenza; Olas, Beata; Kontek, Bogdan; Nazzaro, Filomena; Bifulco, Giuseppe; Piacente, Sonia
DFT/NMR Approach for the Configuration Assignment of Groups of Stereoisomers by the Combination and Comparison of Experimental and Predicted Sets of Data
2020 Lauro, G.; Das, P.; Riccio, R.; Reddy, D. S.; Bifulco, G.
Dihydroaurones and Isoflavan Derivatives from the Roots of Glycyrrhiza asymmetrica
2025 Çevik, Dicle; Masullo, Milena; Lauro, Gianluigi; Napolitano, Assunta; Martucciello, Stefania; Paolella, Gaetana; Polcaro, Luciana Maria; Bifulco, Giuseppe; Kırmızıbekmez, Hasan; Piacente, Sonia
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 2-Substituted 1,5-benzothiazepine-based HDAC inhibitors exert anticancer activities on human solid and acute myeloid leukemia cell lines | 1-gen-2023 | De Vita, Simona; Meninno, Sara; Capasso, Lucia; Colarusso, Ester; Chini, Maria Giovanna; Lauro, Gianluigi; Rinaldi, Romolo; De Cicco, Annalisa; Sian, Veronica; Terracciano, Stefania; Nebbioso, Angela; Lattanzi, Alessandra; Bifulco, Giuseppe | |
| 5-methyl-2-carboxamidepyrrole-based novel dual mPGES-1/sEH inhibitors as promising anticancer candidates | 1-gen-2025 | Colarusso, E.; Lauro, G.; Potenza, M.; Galatello, P.; Garigliota, M. L. D.; Ferraro, M. G.; Piccolo, M.; Chini, M. G.; Irace, C.; Campiglia, P.; Hoffstetter, R. K.; Werz, O.; Ramunno, A.; Bifulco, G. | |
| 6-Methylquinazolin-4(3H)-one Based Compounds as BRD9 Epigenetic Reader Binders: A Rational Combination of in silico Studies and Chemical Synthesis | 1-gen-2022 | Colarusso, E; Gazzillo, E; Boccia, E; Giordano, A; Chini, Mg; Bifulco, G; Lauro, G | |
| 9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain | 1-gen-2015 | Picaud, Sarah; Strocchia, Maria; Terracciano, Stefania; Lauro, Gianluigi; Mendez, Jacqui; Daniels, Danette L; Riccio, Raffaele; Bifulco, Giuseppe; Bruno, Ines; Filippakopoulos, Panagis | |
| A Classic Photochemical Approach Inducing an Unexpected Rearrangement: Exploring the Photoreactivity of Pentacyclic Triterpenic Acids | 1-gen-2023 | Rogati, F.; Maioli, C.; Lauro, G.; Caprioglio, D.; Imperio, D.; Del Grosso, E.; Botta, B.; Mannina, L.; Bifulco, G.; Ingallina, C.; Minassi, A. | |
| A Combinatorial Virtual Screening Approach Driving the Synthesis of 2,4-Thiazolidinedione-Based Molecules as New Dual mPGES-1/5-LO Inhibitors | 1-gen-2020 | Lauro, G.; Terracciano, S.; Cantone, V.; Ruggiero, D.; Fischer, K.; Pace, S.; Werz, O.; Bruno, I.; Bifulco, G. | |
| A Comprehensive In Vitro Characterization of a New Class of Indole-Based Compounds Developed as Selective Haspin Inhibitors | 1-gen-2024 | Vestuto, Vincenzo; Ciaglia, Tania; Musella, Simona; Di Sarno, Veronica; Smaldone, Gerardina; Di Matteo, Francesca; Scala, Maria Carmina; Napolitano, Valeria; Miranda, Maria Rosaria; Amodio, Giuseppina; Novi, Sara; Pepe, Giacomo; Basilicata, Manuela Giovanna; Gazzillo, Erica; Pace, Simona; Gomez-Monterrey, Isabel M.; Sala, Marina; Bifulco, Giuseppe; Tecce, Mario Felice; Campiglia, Pietro; Ostacolo, Carmine; Lauro, Gianluigi; Manfra, Michele; Bertamino, Alessia | |
| Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19) | 1-gen-2020 | De Vita, S.; Chini, M. G.; Lauro, G.; Bifulco, G. | |
| Addressing the Target Identification and Accelerating the Repositioning of Anti-Inflammatory/Anti-Cancer Organic Compounds by Computational Approaches | 1-gen-2021 | Chini, M. G.; Lauro, G.; Bifulco, G. | |
| Anti-inflammatory trends of new benzimidazole derivatives | 1-gen-2016 | Bukhari, Syed Nasir Abbas; Lauro, Gianluigi; Jantan, Ibrahim; Chee, Chin Fei; Amjad, Muhammad Wahab; Bifulco, Giuseppe; Sher, Hassan; Abdullah, Iskandar; Rahman, Noorsaadah Abd | |
| Biological Profile of Two Gentiana lutea L. Metabolites Using Computational Approaches and In Vitro Tests | 1-gen-2021 | DE VITA, Simona; Giovanna Chini, Maria; Saviano, Gabriella; Finamore, Claudia; Festa, Carmen; Lauro, Gianluigi; De Marino, Simona; Russo, Roberto; Avagliano, Carmen; Casapullo, Agostino; Calignano, Antonio; Bifulco, Giuseppe; Iorizzi, Maria | |
| Bissubvilides A and B, Cembrane-capnosane heterodimers from the soft coral sarcophyton subviride | 1-gen-2016 | Sun, Peng; Yu, Qing; Li, Jiao; Riccio, Raffaele; Lauro, Gianluigi; Bifulco, Giuseppe; Kurtán, Tibor; Mándi, Attila; Tang, Hua; Li, Tie Jun; Zhuang, Chun Lin; Gerwick, William H.; Zhang, Wen | |
| Chemical Profiling of Polar Lipids and the Polyphenolic Fraction of Commercial Italian Phaseolus Seeds by UHPLC-HRMS and Biological Evaluation | 1-gen-2024 | Samukha, V.; Fantasma, F.; D'Urso, G.; Colarusso, E.; Schettino, A.; Marigliano, N.; Chini, M. G.; Saviano, G.; De Felice, V.; Lauro, G.; Maione, F.; Bifulco, G.; Casapullo, A.; Iorizzi, M. | |
| Chemical proteomics reveals HSP70 1A as a target for the anticancer diterpene oridonin in Jurkat cells | 1-gen-2013 | DAL PIAZ, Fabrizio; Cotugno, Roberta; Lepore, Laura; Vassallo, Antonio; Malafronte, Nicola; Lauro, Gianluigi; Bifulco, Giuseppe; Belisario, MARIA ANTONIETTA; DE TOMMASI, Nunziatina | |
| Chemistry and Selective Tumor Cell Growth Inhibitory Activity of Polyketides from the South China Sea Sponge Plakortis sp | 1-gen-2017 | Li, Jiao; Li, Cui; Riccio, Raffaele; Lauro, Gianluigi; Bifulco, Giuseppe; Li, Tie Jun; Tang, Hua; Zhuang, Chun Lin; Ma, Hao; Sun, Peng; Zhang, Wen | |
| Chemoproteomics Reveals USP5 (Ubiquitin Carboxyl-Terminal Hydrolase 5) as Promising Target of the Marine Polyketide Gracilioether A | 1-gen-2024 | Capuano, A.; D'Urso, G.; Aliberti, M.; Ruggiero, D.; Terracciano, S.; Festa, C.; Tosco, A.; Chini, M. G.; Lauro, G.; Bifulco, G.; Casapullo, A. | |
| Corylus avellana: A Source of Diarylheptanoids With α-Glucosidase Inhibitory Activity Evaluated by in vitro and in silico Studies | 1-gen-2022 | Masullo, M.; Lauro, G.; Cerulli, A.; Bifulco, G.; Piacente, S. | |
| Cyclic Diarylheptanoids from Corylus avellana Green Leafy Covers: Determination of Their Absolute Configurations and Evaluation of Their Antioxidant and Antimicrobial Activities | 1-gen-2017 | Cerulli, Antonietta; Lauro, Gianluigi; Masullo, Milena; Cantone, Vincenza; Olas, Beata; Kontek, Bogdan; Nazzaro, Filomena; Bifulco, Giuseppe; Piacente, Sonia | |
| DFT/NMR Approach for the Configuration Assignment of Groups of Stereoisomers by the Combination and Comparison of Experimental and Predicted Sets of Data | 1-gen-2020 | Lauro, G.; Das, P.; Riccio, R.; Reddy, D. S.; Bifulco, G. | |
| Dihydroaurones and Isoflavan Derivatives from the Roots of Glycyrrhiza asymmetrica | 1-gen-2025 | Çevik, Dicle; Masullo, Milena; Lauro, Gianluigi; Napolitano, Assunta; Martucciello, Stefania; Paolella, Gaetana; Polcaro, Luciana Maria; Bifulco, Giuseppe; Kırmızıbekmez, Hasan; Piacente, Sonia |