MILITE, Ciro
MILITE, Ciro
Dipartimento di Farmacia/DIFARMA
4-Substituted Benzenesulfonamides Incorporating Bi/Tricyclic Moieties Act as Potent and Isoform-Selective Carbonic Anhydrase II/IX Inhibitors
2018-01-01 Salerno, Silvia; Barresi, Elisabetta; Amendola, Giorgio; Berrino, Emanuela; Milite, Ciro; Marini, Anna Maria; DA SETTIMO PASSETTI, Federico; Novellino, Ettore; Supuran, Claudiu T.; Cosconati, Sandro; Taliani, Sabrina
A continuous-flow synthesis of 1,4-benzodiazepin-5-ones, privileged scaffolds for drug discovery
2015-01-01 Viviano, Monica; Milite, Ciro; Rescigno, Donatella; Castellano, Sabrina; Sbardella, Gianluca
A continuous-flow synthesis of 1,4-benzodiazepin-5-ones, privileged scaffolds for drug discovery.
2015-01-01 Rescigno, Donatella; Viviano, Monica; Milite, Ciro; Sbardella, Gianluca; Castellano, Sabrina
A novel cell-permeable, selective and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruning/classical isosterism approach
2015-01-01 Milite, Ciro; Feoli, Alessandra; Kazuki, Sasaki; Valeria, La Pietra; Balzano, AMODIO LUCA; Luciana, Marinelli; Antonello, Mai; Ettore, Novellino; Castellano, Sabrina; Tosco, Alessandra; Sbardella, Gianluca
Age-dependent attenuation of spatial memory deficits by the histone acetyltransferase p300/CBP-associated factor (PCAF) in 3xTG Alzheimer's disease mice
2022-01-01 Creighton, Samantha D.; Jardine, Kristen H.; Desimone, Alexa; Zmetana, Megan; Castellano, Sabrina; Milite, Ciro; Sbardella, Gianluca; Winters, Boyer D.
Antifungal activity of azole compounds CPA18 and CPA109 against azole-susceptible and -resistant strains of Candida albicans
2013-01-01 Calabrese, ELENA CONCETTA; Castellano, Sabrina; M., Santoriello; C., Sgherri; M. F., Quartacci; L., Calucci; A. G. S., Warrilow; D. C., Lamb; S. L., Kelly; Milite, Ciro; Granata, Ilaria; Sbardella, Gianluca; G., Stefancich; Maresca, Bruno; Porta, Amalia
Biomolecular and biophysical approaches to interrogate p300: a platform for drug discovery.
2015-01-01 Feoli, Alessandra; Milite, Ciro; Tosco, Alessandra; Castellano, Sabrina; Sbardella, Gianluca
CARM1 modulators affect epigenome of stem cells and change morphology of nucleoli
2015-01-01 Franek, M; Legartová, S; Suchánková, J; Milite, Ciro; Castellano, Sabrina; Sbardella, Gianluca; Kozubek, S; Bártová, E.
ChemInform Abstract: A Continuous-Flow Synthesis of 1,4-Benzodiazepin-5-ones, Privileged Scaffolds for Drug Discovery
2015-01-01 Viviano, Monica; Milite, Ciro; Rescigno, Donatella; Castellano, Sabrina; Sbardella, Gianluca
ChemInform Abstract: Progress in the Development of Lysine Methyltransferase SETD8 Inhibitors
2016-01-01 Milite, Ciro; Feoli, Alessandra; Viviano, Monica; Rescigno, Donatella; Mai, Antonello; Castellano, Sabrina; Sbardella, Gianluca
Design, Synthesis and Biological Evaluation of Carboxy Analogues of Arginine Methyltransferase Inhibitor 1 (AMI-1)
2010-01-01 Castellano, Sabrina; Milite, Ciro; Ragno, R; Simeoni, S; Mai, A; Limongelli, V; Novellino, E; Bauer, I; Brosch, G; Spannhoff, A; Cheng, Dh; Bedford, Mt; Sbardella, Gianluca
Design, synthesis and biological evaluation of new selective arginine methyltransferases (PRMTs) Inhibitors
2018-01-01 Milite, C.; Feoli, A.; Rescigno, D.; Clarke, S.; Castellano, S.; Sbardella, G.
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL G9A INHIBITORS FROM A SCAFFOLD HOPPING APPROACH
2016-01-01 Rescigno, Donatella; Milite, Ciro; Viviano, Monica; Castellano, Sabrina; Sbardella, Gianluca
Design, synthesis and biological evaluation of novel G9a inhibitors with improved brain permeability from a scaffold hopping approach
2017-01-01 Rescigno, Donatella; Milite, Ciro; Viviano, Monica; Feoli, Alessandra; Castellano, Sabrina; Sbardella, Gianluca
Design, synthesis and biological evaluation of pyrrole derivatives as coactivator associated arginine methyltransferase 1 (CARM1) inhibitors
2015-01-01 Cianciulli, Agostino; Milite, Ciro; Castellano, Sabrina; Chini, MARIA GIOVANNA; Bifulco, Giuseppe; Xu, Wei; Sbardella, Gianluca
Design, synthesis and in vitro evaluation of bivalent chemical probes for bromo and extra-terminal domain (BET) proteins
2017-01-01 Cipriano, Alessandra; Milite, Ciro; Panagis, Filippakopoulos; Castellano, Sabrina; Sbardella, Gianluca
Design, Synthesis, and Evaluation of New Tripeptides as COX-2 Inhibitors
2013-01-01 Vernieri, Ermelinda; Isabel Gomez, Monterrey; Milite, Ciro; Paolo, Grieco; Musella, Simona; Bertamino, Alessia; Ilaria, Scognamiglio; Stefano, Alcaro; Anna, Artese; Francesco, Ortuso; Ettore, Novellino; Sala, Marina; Campiglia, Pietro
Discovery of a novel chemotype of histone lysine methyltransferase EHMT1/2 (GLP/G9a) inhibitors: rational design, synthesis, biological evaluation and co-crystal structure
2019-01-01 Milite, Ciro; Feoli, Alessandra; Horton, John R; Rescigno, Donatella; Cipriano, Alessandra; Pisapia, Vincenzo; Viviano, Monica; Pepe, Giacomo; Amendola, Giorgio; Novellino, Ettore; Cosconati, Sandro; Cheng, Xiaodong; Castellano, Sabrina; Sbardella, Gianluca
Discovery of benzo[d]imidazole-6-sulfonamides as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain
2022-01-01 Cipriano, Alessandra; Milite, Ciro; Feoli, Alessandra; Viviano, Monica; Pepe, Giacomo; Campiglia, Pietro; Sarno, Giuliana; Picaud, Sarah; Imaide, Satomi; Makukhin, Nikolai; Filippakopoulos, Panagis; Ciulli, Alessio; Castellano, Sabrina; Sbardella, Gianluca
Expanding the quinazoline ring to 3H-benzo[e][1,4]diazepine: development of new and selective G9a inhibitors
2018-01-01 Milite, C.; Feoli, A.; Rescigno, Donatella; Pisapia, Vincenzo; Cosconati, S.; Castellano, S.; Sbardella, G.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 4-Substituted Benzenesulfonamides Incorporating Bi/Tricyclic Moieties Act as Potent and Isoform-Selective Carbonic Anhydrase II/IX Inhibitors | 1-gen-2018 | Salerno, Silvia; Barresi, Elisabetta; Amendola, Giorgio; Berrino, Emanuela; Milite, Ciro; Marini, Anna Maria; DA SETTIMO PASSETTI, Federico; Novellino, Ettore; Supuran, Claudiu T.; Cosconati, Sandro; Taliani, Sabrina | |
| A continuous-flow synthesis of 1,4-benzodiazepin-5-ones, privileged scaffolds for drug discovery | 1-gen-2015 | Viviano, Monica; Milite, Ciro; Rescigno, Donatella; Castellano, Sabrina; Sbardella, Gianluca | |
| A continuous-flow synthesis of 1,4-benzodiazepin-5-ones, privileged scaffolds for drug discovery. | 1-gen-2015 | Rescigno, Donatella; Viviano, Monica; Milite, Ciro; Sbardella, Gianluca; Castellano, Sabrina | |
| A novel cell-permeable, selective and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruning/classical isosterism approach | 1-gen-2015 | Milite, Ciro; Feoli, Alessandra; Kazuki, Sasaki; Valeria, La Pietra; Balzano, AMODIO LUCA; Luciana, Marinelli; Antonello, Mai; Ettore, Novellino; Castellano, Sabrina; Tosco, Alessandra; Sbardella, Gianluca | |
| Age-dependent attenuation of spatial memory deficits by the histone acetyltransferase p300/CBP-associated factor (PCAF) in 3xTG Alzheimer's disease mice | 1-gen-2022 | Creighton, Samantha D.; Jardine, Kristen H.; Desimone, Alexa; Zmetana, Megan; Castellano, Sabrina; Milite, Ciro; Sbardella, Gianluca; Winters, Boyer D. | |
| Antifungal activity of azole compounds CPA18 and CPA109 against azole-susceptible and -resistant strains of Candida albicans | 1-gen-2013 | Calabrese, ELENA CONCETTA; Castellano, Sabrina; M., Santoriello; C., Sgherri; M. F., Quartacci; L., Calucci; A. G. S., Warrilow; D. C., Lamb; S. L., Kelly; Milite, Ciro; Granata, Ilaria; Sbardella, Gianluca; G., Stefancich; Maresca, Bruno; Porta, Amalia | |
| Biomolecular and biophysical approaches to interrogate p300: a platform for drug discovery. | 1-gen-2015 | Feoli, Alessandra; Milite, Ciro; Tosco, Alessandra; Castellano, Sabrina; Sbardella, Gianluca | |
| CARM1 modulators affect epigenome of stem cells and change morphology of nucleoli | 1-gen-2015 | Franek, M; Legartová, S; Suchánková, J; Milite, Ciro; Castellano, Sabrina; Sbardella, Gianluca; Kozubek, S; Bártová, E. | |
| ChemInform Abstract: A Continuous-Flow Synthesis of 1,4-Benzodiazepin-5-ones, Privileged Scaffolds for Drug Discovery | 1-gen-2015 | Viviano, Monica; Milite, Ciro; Rescigno, Donatella; Castellano, Sabrina; Sbardella, Gianluca | |
| ChemInform Abstract: Progress in the Development of Lysine Methyltransferase SETD8 Inhibitors | 1-gen-2016 | Milite, Ciro; Feoli, Alessandra; Viviano, Monica; Rescigno, Donatella; Mai, Antonello; Castellano, Sabrina; Sbardella, Gianluca | |
| Design, Synthesis and Biological Evaluation of Carboxy Analogues of Arginine Methyltransferase Inhibitor 1 (AMI-1) | 1-gen-2010 | Castellano, Sabrina; Milite, Ciro; Ragno, R; Simeoni, S; Mai, A; Limongelli, V; Novellino, E; Bauer, I; Brosch, G; Spannhoff, A; Cheng, Dh; Bedford, Mt; Sbardella, Gianluca | |
| Design, synthesis and biological evaluation of new selective arginine methyltransferases (PRMTs) Inhibitors | 1-gen-2018 | Milite, C.; Feoli, A.; Rescigno, D.; Clarke, S.; Castellano, S.; Sbardella, G. | |
| DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL G9A INHIBITORS FROM A SCAFFOLD HOPPING APPROACH | 1-gen-2016 | Rescigno, Donatella; Milite, Ciro; Viviano, Monica; Castellano, Sabrina; Sbardella, Gianluca | |
| Design, synthesis and biological evaluation of novel G9a inhibitors with improved brain permeability from a scaffold hopping approach | 1-gen-2017 | Rescigno, Donatella; Milite, Ciro; Viviano, Monica; Feoli, Alessandra; Castellano, Sabrina; Sbardella, Gianluca | |
| Design, synthesis and biological evaluation of pyrrole derivatives as coactivator associated arginine methyltransferase 1 (CARM1) inhibitors | 1-gen-2015 | Cianciulli, Agostino; Milite, Ciro; Castellano, Sabrina; Chini, MARIA GIOVANNA; Bifulco, Giuseppe; Xu, Wei; Sbardella, Gianluca | |
| Design, synthesis and in vitro evaluation of bivalent chemical probes for bromo and extra-terminal domain (BET) proteins | 1-gen-2017 | Cipriano, Alessandra; Milite, Ciro; Panagis, Filippakopoulos; Castellano, Sabrina; Sbardella, Gianluca | |
| Design, Synthesis, and Evaluation of New Tripeptides as COX-2 Inhibitors | 1-gen-2013 | Vernieri, Ermelinda; Isabel Gomez, Monterrey; Milite, Ciro; Paolo, Grieco; Musella, Simona; Bertamino, Alessia; Ilaria, Scognamiglio; Stefano, Alcaro; Anna, Artese; Francesco, Ortuso; Ettore, Novellino; Sala, Marina; Campiglia, Pietro | |
| Discovery of a novel chemotype of histone lysine methyltransferase EHMT1/2 (GLP/G9a) inhibitors: rational design, synthesis, biological evaluation and co-crystal structure | 1-gen-2019 | Milite, Ciro; Feoli, Alessandra; Horton, John R; Rescigno, Donatella; Cipriano, Alessandra; Pisapia, Vincenzo; Viviano, Monica; Pepe, Giacomo; Amendola, Giorgio; Novellino, Ettore; Cosconati, Sandro; Cheng, Xiaodong; Castellano, Sabrina; Sbardella, Gianluca | |
| Discovery of benzo[d]imidazole-6-sulfonamides as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain | 1-gen-2022 | Cipriano, Alessandra; Milite, Ciro; Feoli, Alessandra; Viviano, Monica; Pepe, Giacomo; Campiglia, Pietro; Sarno, Giuliana; Picaud, Sarah; Imaide, Satomi; Makukhin, Nikolai; Filippakopoulos, Panagis; Ciulli, Alessio; Castellano, Sabrina; Sbardella, Gianluca | |
| Expanding the quinazoline ring to 3H-benzo[e][1,4]diazepine: development of new and selective G9a inhibitors | 1-gen-2018 | Milite, C.; Feoli, A.; Rescigno, Donatella; Pisapia, Vincenzo; Cosconati, S.; Castellano, S.; Sbardella, G. |