VIVIANO, MONICA
VIVIANO, MONICA
Dipartimento di Farmacia/DIFARMA
A combined approach of structure-based virtual screening and NMR to interrupt the PD-1/PD-L1 axis: Biphenyl-benzimidazole containing compounds as novel PD-L1 inhibitors
2023-01-01 Donati, Greta; Viviano, Monica; D'Amore, Vincenzo Maria; Cipriano, Alessandra; Diakogiannaki, Isidora; Amato, Jussara; Tomassi, Stefano; Brancaccio, Diego; Russomanno, Pasquale; Di Leva, Francesco Saverio; Arosio, Daniela; Seneci, Pierfausto; Taliani, Sabrina; Magiera-Mularz, Katarzyna; Musielak, Bogdan; Skalniak, Lukasz; Holak, Tad A; Castellano, Sabrina; La Pietra, Valeria; Marinelli, Luciana
A continuous-flow synthesis of 1,4-benzodiazepin-5-ones, privileged scaffolds for drug discovery
2015-01-01 Viviano, Monica; Milite, Ciro; Rescigno, Donatella; Castellano, Sabrina; Sbardella, Gianluca
A continuous-flow synthesis of 1,4-benzodiazepin-5-ones, privileged scaffolds for drug discovery.
2015-01-01 Rescigno, Donatella; Viviano, Monica; Milite, Ciro; Sbardella, Gianluca; Castellano, Sabrina
ChemInform Abstract: A Continuous-Flow Synthesis of 1,4-Benzodiazepin-5-ones, Privileged Scaffolds for Drug Discovery
2015-01-01 Viviano, Monica; Milite, Ciro; Rescigno, Donatella; Castellano, Sabrina; Sbardella, Gianluca
ChemInform Abstract: Progress in the Development of Lysine Methyltransferase SETD8 Inhibitors
2016-01-01 Milite, Ciro; Feoli, Alessandra; Viviano, Monica; Rescigno, Donatella; Mai, Antonello; Castellano, Sabrina; Sbardella, Gianluca
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL G9A INHIBITORS FROM A SCAFFOLD HOPPING APPROACH
2016-01-01 Rescigno, Donatella; Milite, Ciro; Viviano, Monica; Castellano, Sabrina; Sbardella, Gianluca
Design, synthesis and biological evaluation of novel G9a inhibitors with improved brain permeability from a scaffold hopping approach
2017-01-01 Rescigno, Donatella; Milite, Ciro; Viviano, Monica; Feoli, Alessandra; Castellano, Sabrina; Sbardella, Gianluca
Developing Spindlin1 small-molecule inhibitors by using protein microarrays
2017-01-01 Bae, Narkhyun; Viviano, Monica; Su, Xiaonan; Lv, Jie; Cheng, Donghang; Sagum, Cari; Castellano, Sabrina; Bai, Xue; Johnson, Claire; Khalil, Mahmoud Ibrahim; Shen, Jianjun; Chen, Kaifu; Li, Haitao; Sbardella, Gianluca; Bedford, Mark T.
Development of a Microscale Thermophoresis-Based Method for Screening and Characterizing Inhibitors of the Methyl-Lysine Reader Protein MRG15
2021-01-01 Feoli, Alessandra; Pisapia, Vincenzo; Viviano, Monica; Castellano, Sabrina; Bartoschik, Tanja; Sbardella, Gianluca
Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells
2019-01-01 Stazi, Giulia; Battistelli, Cecilia; Piano, Valentina; Mazzone, Roberta; Marrocco, Biagina; Marchese, Sara; Louie, Sharon M.; Zwergel, Clemens; Antonini, Lorenzo; Patsilinakos, Alexandros; Ragno, Rino; Viviano, Monica; Sbardella, Gianluca; Ciogli, Alessia; Fabrizi, Giancarlo; Cirilli, Roberto; Strippoli, Raffaele; Marchetti, Alessandra; Tripodi, Marco; Nomura, Daniel K.; Mattevi, Andrea; Mai, Antonello; Valente, Sergio
Discovery of a novel chemotype of histone lysine methyltransferase EHMT1/2 (GLP/G9a) inhibitors: rational design, synthesis, biological evaluation and co-crystal structure
2019-01-01 Milite, Ciro; Feoli, Alessandra; Horton, John R; Rescigno, Donatella; Cipriano, Alessandra; Pisapia, Vincenzo; Viviano, Monica; Pepe, Giacomo; Amendola, Giorgio; Novellino, Ettore; Cosconati, Sandro; Cheng, Xiaodong; Castellano, Sabrina; Sbardella, Gianluca
Discovery of benzo[d]imidazole-6-sulfonamides as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain
2022-01-01 Cipriano, Alessandra; Milite, Ciro; Feoli, Alessandra; Viviano, Monica; Pepe, Giacomo; Campiglia, Pietro; Sarno, Giuliana; Picaud, Sarah; Imaide, Satomi; Makukhin, Nikolai; Filippakopoulos, Panagis; Ciulli, Alessio; Castellano, Sabrina; Sbardella, Gianluca
Discovery of new chemical probes for the MRG15 chromo domain.
2015-01-01 Viviano, Monica; Castellano, Sabrina; Bedford, Mark T.; Sbardella, Gianluca
Discovery of the first-in-class chemical probe for the Spindlin1 methyl-lysine reader domain
2015-01-01 Viviano, Monica; Castellano, Sabrina; Bedford, Mark T.; Li, Haitao; Sbardella, Gianluca
Essential Principles and Recent Progress in the Development of TSPO PET Ligands for Neuroinflammation Imaging
2022-01-01 Viviano, Monica; Barresi, Elisabetta; Siméon, Fabrice G.; Costa, Barbara; Taliani, Sabrina; Da Settimo, Federico; Pike, Victor W.; Castellano, Sabrina
Exploiting the 4-Phenylquinazoline Scaffold for the Development of High Affinity Fluorescent Probes for the Translocator Protein (TSPO)
2017-01-01 Milite, Ciro; Barresi, Elisabetta; Da Pozzo, Eleonora; Costa, Barbara; Viviano, Monica; Porta, Amalia; Messere, Anna; Sbardella, Gianluca; Da Settimo, Federico; Novellino, Ettore; Cosconati, Sandro; Castellano, Sabrina; Taliani, Sabrina; Martini, Claudia
Identification of a Protein Arginine Methyltransferase 7 (PRMT7)/Protein Arginine Methyltransferase 9 (PRMT9) Inhibitor
2023-01-01 Feoli, Alessandra; Iannelli, Giulia; Cipriano, Alessandra; Milite, Ciro; Shen, Lei; Wang, Zhihao; Hadjikyriacou, Andrea; Lowe, Troy L; Safaeipour, Cyrus; Viviano, Monica; Sarno, Giuliana; Morretta, Elva; Monti, Maria Chiara; Yang, Yanzhong; Clarke, Steven G; Cosconati, Sandro; Castellano, Sabrina; Sbardella, Gianluca
Identification of novel small-molecule ligands of methyl-lysine binding protein PHF20
2015-01-01 Viviano, Monica; Castellano, Sabrina; Tosco, Alessandra; Mer, Georges; Bedford, Mark T.; Sbardella, Gianluca
Identification of Small-Molecule Enhancers of Arginine Methylation Catalyzed by Coactivator-Associated Arginine Methyltransferase 1
2012-01-01 Castellano, Sabrina; Spannhoff, Astrid; Milite, Ciro; DAL PIAZ, Fabrizio; Cheng, Donghang; Tosco, Alessandra; Viviano, Monica; Yamani, Abdellah; Cianciulli, Agostino; Sala, Marina; Cura, Vincent; Cavarelli, Jean; Novellino, Ettore; Mai, Antonello; Bedford, Mark T.; Sbardella, Gianluca
Identification of Structural Features of 2-Alkylidene-1,3-Dicarbonyl Derivatives that Induce Inhibition and/or Activation of Histone Acetyltransferases KAT3B/p300 and KAT2B/PCAF
2015-01-01 Castellano, Sabrina; Milite, Ciro; Feoli, Alessandra; Viviano, Monica; Antonello, Mai; Ettore, Novellino; Tosco, Alessandra; Sbardella, Gianluca
Titolo | Data di pubblicazione | Autore(i) | File |
---|---|---|---|
A combined approach of structure-based virtual screening and NMR to interrupt the PD-1/PD-L1 axis: Biphenyl-benzimidazole containing compounds as novel PD-L1 inhibitors | 1-gen-2023 | Donati, Greta; Viviano, Monica; D'Amore, Vincenzo Maria; Cipriano, Alessandra; Diakogiannaki, Isidora; Amato, Jussara; Tomassi, Stefano; Brancaccio, Diego; Russomanno, Pasquale; Di Leva, Francesco Saverio; Arosio, Daniela; Seneci, Pierfausto; Taliani, Sabrina; Magiera-Mularz, Katarzyna; Musielak, Bogdan; Skalniak, Lukasz; Holak, Tad A; Castellano, Sabrina; La Pietra, Valeria; Marinelli, Luciana | |
A continuous-flow synthesis of 1,4-benzodiazepin-5-ones, privileged scaffolds for drug discovery | 1-gen-2015 | Viviano, Monica; Milite, Ciro; Rescigno, Donatella; Castellano, Sabrina; Sbardella, Gianluca | |
A continuous-flow synthesis of 1,4-benzodiazepin-5-ones, privileged scaffolds for drug discovery. | 1-gen-2015 | Rescigno, Donatella; Viviano, Monica; Milite, Ciro; Sbardella, Gianluca; Castellano, Sabrina | |
ChemInform Abstract: A Continuous-Flow Synthesis of 1,4-Benzodiazepin-5-ones, Privileged Scaffolds for Drug Discovery | 1-gen-2015 | Viviano, Monica; Milite, Ciro; Rescigno, Donatella; Castellano, Sabrina; Sbardella, Gianluca | |
ChemInform Abstract: Progress in the Development of Lysine Methyltransferase SETD8 Inhibitors | 1-gen-2016 | Milite, Ciro; Feoli, Alessandra; Viviano, Monica; Rescigno, Donatella; Mai, Antonello; Castellano, Sabrina; Sbardella, Gianluca | |
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL G9A INHIBITORS FROM A SCAFFOLD HOPPING APPROACH | 1-gen-2016 | Rescigno, Donatella; Milite, Ciro; Viviano, Monica; Castellano, Sabrina; Sbardella, Gianluca | |
Design, synthesis and biological evaluation of novel G9a inhibitors with improved brain permeability from a scaffold hopping approach | 1-gen-2017 | Rescigno, Donatella; Milite, Ciro; Viviano, Monica; Feoli, Alessandra; Castellano, Sabrina; Sbardella, Gianluca | |
Developing Spindlin1 small-molecule inhibitors by using protein microarrays | 1-gen-2017 | Bae, Narkhyun; Viviano, Monica; Su, Xiaonan; Lv, Jie; Cheng, Donghang; Sagum, Cari; Castellano, Sabrina; Bai, Xue; Johnson, Claire; Khalil, Mahmoud Ibrahim; Shen, Jianjun; Chen, Kaifu; Li, Haitao; Sbardella, Gianluca; Bedford, Mark T. | |
Development of a Microscale Thermophoresis-Based Method for Screening and Characterizing Inhibitors of the Methyl-Lysine Reader Protein MRG15 | 1-gen-2021 | Feoli, Alessandra; Pisapia, Vincenzo; Viviano, Monica; Castellano, Sabrina; Bartoschik, Tanja; Sbardella, Gianluca | |
Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells | 1-gen-2019 | Stazi, Giulia; Battistelli, Cecilia; Piano, Valentina; Mazzone, Roberta; Marrocco, Biagina; Marchese, Sara; Louie, Sharon M.; Zwergel, Clemens; Antonini, Lorenzo; Patsilinakos, Alexandros; Ragno, Rino; Viviano, Monica; Sbardella, Gianluca; Ciogli, Alessia; Fabrizi, Giancarlo; Cirilli, Roberto; Strippoli, Raffaele; Marchetti, Alessandra; Tripodi, Marco; Nomura, Daniel K.; Mattevi, Andrea; Mai, Antonello; Valente, Sergio | |
Discovery of a novel chemotype of histone lysine methyltransferase EHMT1/2 (GLP/G9a) inhibitors: rational design, synthesis, biological evaluation and co-crystal structure | 1-gen-2019 | Milite, Ciro; Feoli, Alessandra; Horton, John R; Rescigno, Donatella; Cipriano, Alessandra; Pisapia, Vincenzo; Viviano, Monica; Pepe, Giacomo; Amendola, Giorgio; Novellino, Ettore; Cosconati, Sandro; Cheng, Xiaodong; Castellano, Sabrina; Sbardella, Gianluca | |
Discovery of benzo[d]imidazole-6-sulfonamides as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain | 1-gen-2022 | Cipriano, Alessandra; Milite, Ciro; Feoli, Alessandra; Viviano, Monica; Pepe, Giacomo; Campiglia, Pietro; Sarno, Giuliana; Picaud, Sarah; Imaide, Satomi; Makukhin, Nikolai; Filippakopoulos, Panagis; Ciulli, Alessio; Castellano, Sabrina; Sbardella, Gianluca | |
Discovery of new chemical probes for the MRG15 chromo domain. | 1-gen-2015 | Viviano, Monica; Castellano, Sabrina; Bedford, Mark T.; Sbardella, Gianluca | |
Discovery of the first-in-class chemical probe for the Spindlin1 methyl-lysine reader domain | 1-gen-2015 | Viviano, Monica; Castellano, Sabrina; Bedford, Mark T.; Li, Haitao; Sbardella, Gianluca | |
Essential Principles and Recent Progress in the Development of TSPO PET Ligands for Neuroinflammation Imaging | 1-gen-2022 | Viviano, Monica; Barresi, Elisabetta; Siméon, Fabrice G.; Costa, Barbara; Taliani, Sabrina; Da Settimo, Federico; Pike, Victor W.; Castellano, Sabrina | |
Exploiting the 4-Phenylquinazoline Scaffold for the Development of High Affinity Fluorescent Probes for the Translocator Protein (TSPO) | 1-gen-2017 | Milite, Ciro; Barresi, Elisabetta; Da Pozzo, Eleonora; Costa, Barbara; Viviano, Monica; Porta, Amalia; Messere, Anna; Sbardella, Gianluca; Da Settimo, Federico; Novellino, Ettore; Cosconati, Sandro; Castellano, Sabrina; Taliani, Sabrina; Martini, Claudia | |
Identification of a Protein Arginine Methyltransferase 7 (PRMT7)/Protein Arginine Methyltransferase 9 (PRMT9) Inhibitor | 1-gen-2023 | Feoli, Alessandra; Iannelli, Giulia; Cipriano, Alessandra; Milite, Ciro; Shen, Lei; Wang, Zhihao; Hadjikyriacou, Andrea; Lowe, Troy L; Safaeipour, Cyrus; Viviano, Monica; Sarno, Giuliana; Morretta, Elva; Monti, Maria Chiara; Yang, Yanzhong; Clarke, Steven G; Cosconati, Sandro; Castellano, Sabrina; Sbardella, Gianluca | |
Identification of novel small-molecule ligands of methyl-lysine binding protein PHF20 | 1-gen-2015 | Viviano, Monica; Castellano, Sabrina; Tosco, Alessandra; Mer, Georges; Bedford, Mark T.; Sbardella, Gianluca | |
Identification of Small-Molecule Enhancers of Arginine Methylation Catalyzed by Coactivator-Associated Arginine Methyltransferase 1 | 1-gen-2012 | Castellano, Sabrina; Spannhoff, Astrid; Milite, Ciro; DAL PIAZ, Fabrizio; Cheng, Donghang; Tosco, Alessandra; Viviano, Monica; Yamani, Abdellah; Cianciulli, Agostino; Sala, Marina; Cura, Vincent; Cavarelli, Jean; Novellino, Ettore; Mai, Antonello; Bedford, Mark T.; Sbardella, Gianluca | |
Identification of Structural Features of 2-Alkylidene-1,3-Dicarbonyl Derivatives that Induce Inhibition and/or Activation of Histone Acetyltransferases KAT3B/p300 and KAT2B/PCAF | 1-gen-2015 | Castellano, Sabrina; Milite, Ciro; Feoli, Alessandra; Viviano, Monica; Antonello, Mai; Ettore, Novellino; Tosco, Alessandra; Sbardella, Gianluca |