Colarusso, Ester
Colarusso, Ester
Dipartimento di Farmacia/DIFARMA
2-Substituted 1,5-benzothiazepine-based HDAC inhibitors exert anticancer activities on human solid and acute myeloid leukemia cell lines
2023 De Vita, Simona; Meninno, Sara; Capasso, Lucia; Colarusso, Ester; Chini, Maria Giovanna; Lauro, Gianluigi; Rinaldi, Romolo; De Cicco, Annalisa; Sian, Veronica; Terracciano, Stefania; Nebbioso, Angela; Lattanzi, Alessandra; Bifulco, Giuseppe
5-methyl-2-carboxamidepyrrole-based novel dual mPGES-1/sEH inhibitors as promising anticancer candidates
2025 Colarusso, E.; Lauro, G.; Potenza, M.; Galatello, P.; Garigliota, M. L. D.; Ferraro, M. G.; Piccolo, M.; Chini, M. G.; Irace, C.; Campiglia, P.; Hoffstetter, R. K.; Werz, O.; Ramunno, A.; Bifulco, G.
6-Methylquinazolin-4(3H)-one Based Compounds as BRD9 Epigenetic Reader Binders: A Rational Combination of in silico Studies and Chemical Synthesis
2022 Colarusso, E; Gazzillo, E; Boccia, E; Giordano, A; Chini, Mg; Bifulco, G; Lauro, G
Chemical Profiling of Polar Lipids and the Polyphenolic Fraction of Commercial Italian Phaseolus Seeds by UHPLC-HRMS and Biological Evaluation
2024 Samukha, V.; Fantasma, F.; D'Urso, G.; Colarusso, E.; Schettino, A.; Marigliano, N.; Chini, M. G.; Saviano, G.; De Felice, V.; Lauro, G.; Maione, F.; Bifulco, G.; Casapullo, A.; Iorizzi, M.
Essential Oils of Laurus nobilis L.: From Chemical Analysis to In Silico Investigation of Anti-Inflammatory Activity by Soluble Epoxide Hydrolase (sEH) Inhibition
2024 Fantasma, F.; Samukha, V.; Aliberti, M.; Colarusso, E.; Chini, M. G.; Saviano, G.; De Felice, V.; Lauro, G.; Casapullo, A.; Bifulco, G.; Iorizzi, M.
Exploring the chemical space of functionalized [1,2,4]triazolo[4,3-a]quinoxaline-based compounds targeting the bromodomain of BRD9
2023 Gazzillo, Erica; Pierri, Martina; Colarusso, Ester; Chini, Maria Giovanna; Ferraro, Maria Grazia; Piccolo, Marialuisa; Irace, Carlo; Bruno, Ines; Bifulco, Giuseppe; Terracciano, Stefania; Lauro, Gianluigi
Identification and Development of BRD9 Chemical Probes
2024 Colarusso, E.; Chini, M. G.; Bifulco, G.; Lauro, G.; Giordano, A.
Identification of 2,4,5-trisubstituted-2,4-dihydro-3H-1,2,4-triazol-3-one-based small molecules as selective BRD9 binders
2023 Colarusso, Ester; Ceccacci, Sara; Monti, Maria Chiara; Gazzillo, Erica; Giordano, Assunta; Chini, Maria Giovanna; Ferraro, Maria Grazia; Piccolo, Marialuisa; Ruggiero, Dafne; Irace, Carlo; Terracciano, Stefania; Bruno, Ines; Bifulco, Giuseppe; Lauro, Gianluigi
Identification of Novel Bromodomain-Containing Protein 4 (BRD4) Binders through 3D Pharmacophore-Based Repositioning Screening Campaign
2024 Colarusso, E.; Gazzillo, E.; Boccia, E.; Terracciano, S.; Bruno, I.; Bifulco, G.; Chini, M. G.; Lauro, G.
In Silico Design, Chemical Synthesis, Biophysical and in Vitro Evaluation for the Identification of 1-Ethyl-1H-Pyrazolo[3,4-b]Pyridine-Based BRD9 Binders
2024 Colarusso, E.; Gazzillo, E.; Pierri, M.; Ruggiero, D.; Chini, M. G.; Bruno, I.; Bifulco, G.; Terracciano, S.; Lauro, G.
Investigation analysis of the phytochemical composition of Laurus nobilis L. leaves essential oil: a study of the antioxidant and anti-inflammatory properties using a combination of in vitro and in silico methods
2024 Fantasma, Francesca; Samukha, Vadym; Aliberti, Michela; Colarusso, Ester; Saviano, Gabriella; De Felice, Vincenzo; Lauro, Gianluigi; Casapullo, Agostino; Giovanna Chini, Maria; Bifulco, Giuseppe; Iorizzi, Maria
PharmaCore: The Automatic Generation of 3D Structure-Based Pharmacophore Models from Protein/Ligand Complexes
2024 De Vita, S.; Colarusso, E.; Chini, M. G.; Bifulco, G.; Lauro, G.
Repositioning of Small Molecules through the Inverse Virtual Screening in silico Tool: Case of Benzothiazole-Based Inhibitors of Soluble Epoxide Hydrolase (sEH)
2024 Gazzillo, E.; Colarusso, E.; Giordano, A.; Chini, M. G.; Potenza, M.; Hofstetter, R. K.; Iorizzi, M.; Werz, O.; Lauro, G.; Bifulco, G.
Targeting mPGES-1 by a Combinatorial Approach: Identification of the Aminobenzothiazole Scaffold to Suppress PGE2Levels
2020 Chini, M. G.; Giordano, A.; Potenza, M.; Terracciano, S.; Fischer, K.; Vaccaro, M. C.; Colarusso, E.; Bruno, I.; Riccio, R.; Koeberle, A.; Werz, O.; Bifulco, G.
Thiazolidin-4-one-based compounds interfere with the eicosanoid biosynthesis pathways by mPGES-1/sEH/5-LO multi-target inhibition
2022 Colarusso, Ester; Potenza, Marianna; Lauro, Gianluigi; Giovanna Chini, Maria; Sepe, Valentina; Zampella, Angela; Fischer, Katrin; Hofstetter, Robert K.; Werz, Oliver; Bifulco, Giuseppe
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 2-Substituted 1,5-benzothiazepine-based HDAC inhibitors exert anticancer activities on human solid and acute myeloid leukemia cell lines | 1-gen-2023 | De Vita, Simona; Meninno, Sara; Capasso, Lucia; Colarusso, Ester; Chini, Maria Giovanna; Lauro, Gianluigi; Rinaldi, Romolo; De Cicco, Annalisa; Sian, Veronica; Terracciano, Stefania; Nebbioso, Angela; Lattanzi, Alessandra; Bifulco, Giuseppe | |
| 5-methyl-2-carboxamidepyrrole-based novel dual mPGES-1/sEH inhibitors as promising anticancer candidates | 1-gen-2025 | Colarusso, E.; Lauro, G.; Potenza, M.; Galatello, P.; Garigliota, M. L. D.; Ferraro, M. G.; Piccolo, M.; Chini, M. G.; Irace, C.; Campiglia, P.; Hoffstetter, R. K.; Werz, O.; Ramunno, A.; Bifulco, G. | |
| 6-Methylquinazolin-4(3H)-one Based Compounds as BRD9 Epigenetic Reader Binders: A Rational Combination of in silico Studies and Chemical Synthesis | 1-gen-2022 | Colarusso, E; Gazzillo, E; Boccia, E; Giordano, A; Chini, Mg; Bifulco, G; Lauro, G | |
| Chemical Profiling of Polar Lipids and the Polyphenolic Fraction of Commercial Italian Phaseolus Seeds by UHPLC-HRMS and Biological Evaluation | 1-gen-2024 | Samukha, V.; Fantasma, F.; D'Urso, G.; Colarusso, E.; Schettino, A.; Marigliano, N.; Chini, M. G.; Saviano, G.; De Felice, V.; Lauro, G.; Maione, F.; Bifulco, G.; Casapullo, A.; Iorizzi, M. | |
| Essential Oils of Laurus nobilis L.: From Chemical Analysis to In Silico Investigation of Anti-Inflammatory Activity by Soluble Epoxide Hydrolase (sEH) Inhibition | 1-gen-2024 | Fantasma, F.; Samukha, V.; Aliberti, M.; Colarusso, E.; Chini, M. G.; Saviano, G.; De Felice, V.; Lauro, G.; Casapullo, A.; Bifulco, G.; Iorizzi, M. | |
| Exploring the chemical space of functionalized [1,2,4]triazolo[4,3-a]quinoxaline-based compounds targeting the bromodomain of BRD9 | 1-gen-2023 | Gazzillo, Erica; Pierri, Martina; Colarusso, Ester; Chini, Maria Giovanna; Ferraro, Maria Grazia; Piccolo, Marialuisa; Irace, Carlo; Bruno, Ines; Bifulco, Giuseppe; Terracciano, Stefania; Lauro, Gianluigi | |
| Identification and Development of BRD9 Chemical Probes | 1-gen-2024 | Colarusso, E.; Chini, M. G.; Bifulco, G.; Lauro, G.; Giordano, A. | |
| Identification of 2,4,5-trisubstituted-2,4-dihydro-3H-1,2,4-triazol-3-one-based small molecules as selective BRD9 binders | 1-gen-2023 | Colarusso, Ester; Ceccacci, Sara; Monti, Maria Chiara; Gazzillo, Erica; Giordano, Assunta; Chini, Maria Giovanna; Ferraro, Maria Grazia; Piccolo, Marialuisa; Ruggiero, Dafne; Irace, Carlo; Terracciano, Stefania; Bruno, Ines; Bifulco, Giuseppe; Lauro, Gianluigi | |
| Identification of Novel Bromodomain-Containing Protein 4 (BRD4) Binders through 3D Pharmacophore-Based Repositioning Screening Campaign | 1-gen-2024 | Colarusso, E.; Gazzillo, E.; Boccia, E.; Terracciano, S.; Bruno, I.; Bifulco, G.; Chini, M. G.; Lauro, G. | |
| In Silico Design, Chemical Synthesis, Biophysical and in Vitro Evaluation for the Identification of 1-Ethyl-1H-Pyrazolo[3,4-b]Pyridine-Based BRD9 Binders | 1-gen-2024 | Colarusso, E.; Gazzillo, E.; Pierri, M.; Ruggiero, D.; Chini, M. G.; Bruno, I.; Bifulco, G.; Terracciano, S.; Lauro, G. | |
| Investigation analysis of the phytochemical composition of Laurus nobilis L. leaves essential oil: a study of the antioxidant and anti-inflammatory properties using a combination of in vitro and in silico methods | 1-gen-2024 | Fantasma, Francesca; Samukha, Vadym; Aliberti, Michela; Colarusso, Ester; Saviano, Gabriella; De Felice, Vincenzo; Lauro, Gianluigi; Casapullo, Agostino; Giovanna Chini, Maria; Bifulco, Giuseppe; Iorizzi, Maria | |
| PharmaCore: The Automatic Generation of 3D Structure-Based Pharmacophore Models from Protein/Ligand Complexes | 1-gen-2024 | De Vita, S.; Colarusso, E.; Chini, M. G.; Bifulco, G.; Lauro, G. | |
| Repositioning of Small Molecules through the Inverse Virtual Screening in silico Tool: Case of Benzothiazole-Based Inhibitors of Soluble Epoxide Hydrolase (sEH) | 1-gen-2024 | Gazzillo, E.; Colarusso, E.; Giordano, A.; Chini, M. G.; Potenza, M.; Hofstetter, R. K.; Iorizzi, M.; Werz, O.; Lauro, G.; Bifulco, G. | |
| Targeting mPGES-1 by a Combinatorial Approach: Identification of the Aminobenzothiazole Scaffold to Suppress PGE2Levels | 1-gen-2020 | Chini, M. G.; Giordano, A.; Potenza, M.; Terracciano, S.; Fischer, K.; Vaccaro, M. C.; Colarusso, E.; Bruno, I.; Riccio, R.; Koeberle, A.; Werz, O.; Bifulco, G. | |
| Thiazolidin-4-one-based compounds interfere with the eicosanoid biosynthesis pathways by mPGES-1/sEH/5-LO multi-target inhibition | 1-gen-2022 | Colarusso, Ester; Potenza, Marianna; Lauro, Gianluigi; Giovanna Chini, Maria; Sepe, Valentina; Zampella, Angela; Fischer, Katrin; Hofstetter, Robert K.; Werz, Oliver; Bifulco, Giuseppe |