A viable method to obtain calix[8]arenes selectively functionalized at the upper rim of 1,5-aromatic rings is reported. The procedure relies on protected, readily accessible 1,5-xylylene-bridged derivatives, which are easily deprotected by hydrogenolysis. The method allowed the synthesis of the first examples of calix[8]arenes partially substituted with p-nitro, p-amino, quinone and hydroquinone functionalities

Convenient regioselective functionalization at the upper-rim of p-tert-butylcalix[8]arene through a protection-deprotection procedure

GAETA, CARMINE;MARTINO, Marco;NERI, Placido
2002

Abstract

A viable method to obtain calix[8]arenes selectively functionalized at the upper rim of 1,5-aromatic rings is reported. The procedure relies on protected, readily accessible 1,5-xylylene-bridged derivatives, which are easily deprotected by hydrogenolysis. The method allowed the synthesis of the first examples of calix[8]arenes partially substituted with p-nitro, p-amino, quinone and hydroquinone functionalities
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11386/1058724
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 26
  • ???jsp.display-item.citation.isi??? 27
social impact