An operationally simple and mild protocol for the catalytic enantioselective epoxidation of r,â-unsaturated ketones has been estabilished using commercially available r,r-diphenyl-L-prolinol as bifunctional organocatalyst and tert-butyl hydroperoxide (TBHP) as oxidant. The epoxides have been obtained in good yields and with up to 80% ee.

Enantioselective epoxidation of a,b-enones promoted by a,a-diphenyl-L-prolinol as bifunctional organocatalyst

LATTANZI, Alessandra
2005

Abstract

An operationally simple and mild protocol for the catalytic enantioselective epoxidation of r,â-unsaturated ketones has been estabilished using commercially available r,r-diphenyl-L-prolinol as bifunctional organocatalyst and tert-butyl hydroperoxide (TBHP) as oxidant. The epoxides have been obtained in good yields and with up to 80% ee.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11386/1059357
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