A convenient method for double Michael additions to quinone systems catalyzed by Al2O3, is reported. The advantages of this method include the use of a cheap and environment-friendly catalyst, a straightforward isolation of the pure product by filtration, high yields, and excellent selectivity, thus providing rapid access to useful building blocks for the preparation of biologically active quinones.

A practical, green and selective approach toward the synthesis of pharmacologically important quinone-containing heterocyclic systems using alumina-catalyzed Michael addition reaction.

CASTELLANO, Sabrina;BERTAMINO, Alessia;SANTORIELLO, MARISABELLA;CAMPIGLIA, Pietro;SBARDELLA, Gianluca;
2008

Abstract

A convenient method for double Michael additions to quinone systems catalyzed by Al2O3, is reported. The advantages of this method include the use of a cheap and environment-friendly catalyst, a straightforward isolation of the pure product by filtration, high yields, and excellent selectivity, thus providing rapid access to useful building blocks for the preparation of biologically active quinones.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11386/1845457
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