Readily accessible a,a-diarylprolinols have been recently exploited as useful organocatalysts in different asymmetric reactions. It has been proposed that they operate either via bifunctional activation of the reactive partners through non-covalent interactions or via formation of covalent enamine and iminium intermediates. This feature article describes the employment of a,a-diarylprolinols as catalysts in the epoxidation of a,b-enones, aldol reaction, cycloaddition, and carbon–carbon and carbon–heteroatom bond forming reactions.
a,a-Diarylprolinols: Bifunctional Organocatalysts for Asymmetric Synthesis
LATTANZI, Alessandra
2009-01-01
Abstract
Readily accessible a,a-diarylprolinols have been recently exploited as useful organocatalysts in different asymmetric reactions. It has been proposed that they operate either via bifunctional activation of the reactive partners through non-covalent interactions or via formation of covalent enamine and iminium intermediates. This feature article describes the employment of a,a-diarylprolinols as catalysts in the epoxidation of a,b-enones, aldol reaction, cycloaddition, and carbon–carbon and carbon–heteroatom bond forming reactions.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
