Readily accessible a,a-diarylprolinols have been recently exploited as useful organocatalysts in different asymmetric reactions. It has been proposed that they operate either via bifunctional activation of the reactive partners through non-covalent interactions or via formation of covalent enamine and iminium intermediates. This feature article describes the employment of a,a-diarylprolinols as catalysts in the epoxidation of a,b-enones, aldol reaction, cycloaddition, and carbon–carbon and carbon–heteroatom bond forming reactions.

a,a-Diarylprolinols: Bifunctional Organocatalysts for Asymmetric Synthesis

LATTANZI, Alessandra
2009-01-01

Abstract

Readily accessible a,a-diarylprolinols have been recently exploited as useful organocatalysts in different asymmetric reactions. It has been proposed that they operate either via bifunctional activation of the reactive partners through non-covalent interactions or via formation of covalent enamine and iminium intermediates. This feature article describes the employment of a,a-diarylprolinols as catalysts in the epoxidation of a,b-enones, aldol reaction, cycloaddition, and carbon–carbon and carbon–heteroatom bond forming reactions.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11386/2282560
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