Chemical investigation of a red-type Mexican propolis sample has led to the isolation of three new compounds, 1-(30,40-dihydroxy-20-methoxyphenyl)-3-(phenyl)propane (1), (Z)-1-(20-methoxy-40,50-dihydroxyphenyl)-2-(3-phenyl)propene (2) and 3-hydroxy-5,6-dimethoxyflavan (3), together with seven known flavanones, isoflavans, and pterocarpans. Structural determination, was accomplished by spectroscopic analysis, particularly 2D NMR and ESI-MS/MS techniques. The present study appears to be the first report on the occurrence of isoflavonoids in Mexican propolis. In addition, the presence of compounds with a 1,3-diarylpropane and 1,3-diarylpropene carbon skeleton were found for the first time in propolis. Isolated compounds 1-10 indicated the possible relation between red Mexican propolis and the genus Dalbergia.
Chemical constituents of red Mexican propolis
PICCINELLI, ANNA LISA;RASTRELLI, Luca
2010-01-01
Abstract
Chemical investigation of a red-type Mexican propolis sample has led to the isolation of three new compounds, 1-(30,40-dihydroxy-20-methoxyphenyl)-3-(phenyl)propane (1), (Z)-1-(20-methoxy-40,50-dihydroxyphenyl)-2-(3-phenyl)propene (2) and 3-hydroxy-5,6-dimethoxyflavan (3), together with seven known flavanones, isoflavans, and pterocarpans. Structural determination, was accomplished by spectroscopic analysis, particularly 2D NMR and ESI-MS/MS techniques. The present study appears to be the first report on the occurrence of isoflavonoids in Mexican propolis. In addition, the presence of compounds with a 1,3-diarylpropane and 1,3-diarylpropene carbon skeleton were found for the first time in propolis. Isolated compounds 1-10 indicated the possible relation between red Mexican propolis and the genus Dalbergia.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
