Diastereomeric O-beta-glucosides at the primary carbons of glycerol and erythritol have been subjected as their peracetates to enzymatic hydrolysis by PFL. Only acetyl groups of the aglycones are hydrolyzed, the diastereoselectivity being very high on the erythritol derivatives and fair on the glycerol derivatives. The chemical synthesis of (2S,3R)-1-(O-beta-D-glucopyranosyl)-butane-2,3,4-triol heptaacetate is also reported.

Enzymatic regio- and diastereoselective hydrolysis of peracetylated glycerol- and erythritol-β-glucosides

SORIENTE, Annunziata;DE ROSA, Margherita;SODANO, Guido
1995-01-01

Abstract

Diastereomeric O-beta-glucosides at the primary carbons of glycerol and erythritol have been subjected as their peracetates to enzymatic hydrolysis by PFL. Only acetyl groups of the aglycones are hydrolyzed, the diastereoselectivity being very high on the erythritol derivatives and fair on the glycerol derivatives. The chemical synthesis of (2S,3R)-1-(O-beta-D-glucopyranosyl)-butane-2,3,4-triol heptaacetate is also reported.
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11386/3003041
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 7
  • ???jsp.display-item.citation.isi??? 6
social impact