Complexes of scandium, yttrium, samarium and neodymium bearing monoanionic tridentate ancillary ligands have been synthesized and characterized. The cytotoxic activities of novel compounds, as well as that of similar compounds previously reported have been evaluated on rat glioma (C6), murine fibrosarcoma (WHEI-164) and human embryonic kidney (HEK-293) cell lines. Scandium complex with quinolinephenoxyamine (NNHO) ligand showed very interesting activity against C6 cell line.
|Titolo:||Synthesis and cytotoxic activities of group 3 metal complexes having monoanionic tridentate ligands.|
|Autori interni:||SATURNINO, Carmela|
|Data di pubblicazione:||2010|
|Rivista:||EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY|
|Appare nelle tipologie:||1.1.2 Articolo su rivista con ISSN|