Phytochemical investigation of Caralluma adscendens var. gracilis and Caralluma pauciflora (Asclepiadaceae) whole plant extracts allowed to isolate one pregnane glycoside and two pregnanes characterized as 12β,20-O- dibenzoyl-5α,6-dihydrosarcostin β-oleandropyranosyl-(1→4)- β-cymaropyranosyl-(1→4)-β-digitoxypyranosyl-(1→4) -β-cymaropyranosyl-(1→4)-β-cymaropyranoside (1), 12β-O-benzoyl-3β,11α,14β,20R-pentahydroxy-pregn-5-ene (2), and 11α-O-benzoyl-3β,12β,14β,20R-pentahydroxy-pregn-5-ene (3), respectively. Their structural characterization was obtained on the basis of extensive NMR spectral studies. Three known pregnane glycosides along with lupeol and β-sitosterol were also isolated and characterized.

Anti-angiogenic activity evaluation of secondary metabolites from Calycolpus moritzianus leaves.

MALAFRONTE, NICOLA;COTUGNO, ROBERTA;DAL PIAZ, FABRIZIO;DE TOMMASI, Nunziatina
2011

Abstract

Phytochemical investigation of Caralluma adscendens var. gracilis and Caralluma pauciflora (Asclepiadaceae) whole plant extracts allowed to isolate one pregnane glycoside and two pregnanes characterized as 12β,20-O- dibenzoyl-5α,6-dihydrosarcostin β-oleandropyranosyl-(1→4)- β-cymaropyranosyl-(1→4)-β-digitoxypyranosyl-(1→4) -β-cymaropyranosyl-(1→4)-β-cymaropyranoside (1), 12β-O-benzoyl-3β,11α,14β,20R-pentahydroxy-pregn-5-ene (2), and 11α-O-benzoyl-3β,12β,14β,20R-pentahydroxy-pregn-5-ene (3), respectively. Their structural characterization was obtained on the basis of extensive NMR spectral studies. Three known pregnane glycosides along with lupeol and β-sitosterol were also isolated and characterized.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11386/3040528
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