Starfish Saponins, Part 50. Steroidal Glycosides from the Okinawan Starfish Nardoa tuberculata

This paper describes a complete anal. of the glycoside and polyhydroxysteroid constituents of the starfish Nardoa tuberculata, collected at Zampa, Okinawa, Japan. Besides a group of known non-sulfated steroidal diglycosides, halitylosides A and two known polyhydroxysteroids, N. tuberculata also contains four new sulfated steroidal glycosides, e.g. I (R = H, Me), closely related to the previous halitylosides. The antifungal activities and the effects on the development of fertilized sea urchin eggs of some steroid components from this starfish were examd.