Abstract: Three new cycloartane-type triterpene glycosides, brachyosides A (1), B (3), and C (2), from the roots of Astragalus brachypterus and one new glycoside, cyclocephaloside II (4), from the roots of Astragalus microcephalus have been isolated together with five known saponins, astragalosides I, II, and IV, cyclocanthoside E, and cycloastragenol. The structures of the new compounds were established as 3-O-[β-d-xylopyranosyl(1→3)-β-d-xylopyranosyl-6-O-β-d-glucopyranosyl-3β,6α,16β,24(S),25-pentahydroxycycloartane (1), 3-O-β-d-xylopyranosyl-6-O-β-d-glucopyranosyl-24-O-β-d-glucopyranosyl-3β,6α,16β,24(S),25-pentahydroxycycloartane (2), 20(R),24(S)-epoxy-6-O-β-d-glucopyranosyl-3β,6α,16β,25-tetrahydroxycycloartane (3), and 20(R),24(S)-epoxy-3-O-(4‘-O-acetyl)-β-d-xylopyranosyl-6-O-β-d-glucopyranosyl-3β,6α,16β,25-tetrahydroxycycloartane (4). For the structure elucidations, 1D- and 2D-NMR experiments and FABMS were used.

Cycloartane Triterpene Glycosides from the Roots of Astragalus brachypterus and Astragalus microcephalus

AQUINO, Rita Patrizia;PIACENTE, Sonia;PIZZA, Cosimo
1998

Abstract

Abstract: Three new cycloartane-type triterpene glycosides, brachyosides A (1), B (3), and C (2), from the roots of Astragalus brachypterus and one new glycoside, cyclocephaloside II (4), from the roots of Astragalus microcephalus have been isolated together with five known saponins, astragalosides I, II, and IV, cyclocanthoside E, and cycloastragenol. The structures of the new compounds were established as 3-O-[β-d-xylopyranosyl(1→3)-β-d-xylopyranosyl-6-O-β-d-glucopyranosyl-3β,6α,16β,24(S),25-pentahydroxycycloartane (1), 3-O-β-d-xylopyranosyl-6-O-β-d-glucopyranosyl-24-O-β-d-glucopyranosyl-3β,6α,16β,24(S),25-pentahydroxycycloartane (2), 20(R),24(S)-epoxy-6-O-β-d-glucopyranosyl-3β,6α,16β,25-tetrahydroxycycloartane (3), and 20(R),24(S)-epoxy-3-O-(4‘-O-acetyl)-β-d-xylopyranosyl-6-O-β-d-glucopyranosyl-3β,6α,16β,25-tetrahydroxycycloartane (4). For the structure elucidations, 1D- and 2D-NMR experiments and FABMS were used.
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11386/3137377
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 60
  • ???jsp.display-item.citation.isi??? 56
social impact