Abstract: This paper examines the effects of extracts, chromatographic fractions, and pure compounds from Zygophyllum gaetulum (Zygophyllaceae) on electrically-induced contractions of isolated guinea-pig ileum and morphine withdrawal in vitro. The results indicated that all the extracts, partially purified fractions from the MeOH extract and two pure triterpenene saponins, significantly and dose-dependently reduced both the electrical contractions of the ileum and morphine withdrawal. The two active compounds are triterpenene acid bisdesmosides with different sugar residues at C-3 and C-28 of the aglycones.

Properties and Effects on Isolated Guinea-Pig Ileum of Zygophyllum gaetulum Species Endemic in Moroccan Sahara

CAPASSO, Anna;AQUINO, Rita Patrizia
1998

Abstract

Abstract: This paper examines the effects of extracts, chromatographic fractions, and pure compounds from Zygophyllum gaetulum (Zygophyllaceae) on electrically-induced contractions of isolated guinea-pig ileum and morphine withdrawal in vitro. The results indicated that all the extracts, partially purified fractions from the MeOH extract and two pure triterpenene saponins, significantly and dose-dependently reduced both the electrical contractions of the ileum and morphine withdrawal. The two active compounds are triterpenene acid bisdesmosides with different sugar residues at C-3 and C-28 of the aglycones.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11386/3137381
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