Abstract: Two new oleanene glycosides (1–2) possessing hederagenin as the aglycone were isolated from the methanolic extract of the aerial parts of Caltha polypetala together with four known glycosides. The saccharide portion linked to C-3 of the aglycone is made up of α-l-arabinopyranose, α-l-rhamnopyranose and galactopyranose in the new compounds; while compound 1 possesses linked to C-28 a trisaccharide moiety made up of two β-d-glucopyranose and one α-l-rhamnopyranose unit, in compound 2 the 28-COOH group is free. The structures were elucidated by 1D and 2D NMR experiments including 1H–1H (DQF-COSY, 1D-TOCSY, 2D-ROESY) and 1H–13C (HSQC, HMBC) spectroscopy.
Two oleanene glycosides from the aerial parts of Caltha polypetala
AQUINO, Rita Patrizia;PIACENTE, Sonia;PIZZA, Cosimo
1999-01-01
Abstract
Abstract: Two new oleanene glycosides (1–2) possessing hederagenin as the aglycone were isolated from the methanolic extract of the aerial parts of Caltha polypetala together with four known glycosides. The saccharide portion linked to C-3 of the aglycone is made up of α-l-arabinopyranose, α-l-rhamnopyranose and galactopyranose in the new compounds; while compound 1 possesses linked to C-28 a trisaccharide moiety made up of two β-d-glucopyranose and one α-l-rhamnopyranose unit, in compound 2 the 28-COOH group is free. The structures were elucidated by 1D and 2D NMR experiments including 1H–1H (DQF-COSY, 1D-TOCSY, 2D-ROESY) and 1H–13C (HSQC, HMBC) spectroscopy.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
