The reaction of alpha-phenyl-beta-formylacrylic derivatives with various amidines (benzamidine, acetamidine) and heterocyclic amidines (2-aminopyridines, 3-aminopyridazines), yields alpha-substituted imidazolylphenylacetic acids and imidazo[1,2-x] azines bearing a phenylacetic acid residue in position 3. Some mechanistic aspects of the cyclocondensation reaction will be discussed.

Heterocyclic Amidines .1. A One-step Synthesis of New Alpha-substituted Imidazolylphenylacetic Acids

SATURNINO, Carmela;
1995-01-01

Abstract

The reaction of alpha-phenyl-beta-formylacrylic derivatives with various amidines (benzamidine, acetamidine) and heterocyclic amidines (2-aminopyridines, 3-aminopyridazines), yields alpha-substituted imidazolylphenylacetic acids and imidazo[1,2-x] azines bearing a phenylacetic acid residue in position 3. Some mechanistic aspects of the cyclocondensation reaction will be discussed.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11386/3251480
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