Chemotherapy may induce virus B reactivation in patients carriers of HBsAg. The clinical significance of occult B virus (HbcAB positive patients) is still uncertain then it is not clear if chemotherapy may be dangerous also in the case of patients carriers of HBcAB. The evidence reported in this case report on one hand supports the idea of a significant role of occult B virus and on the other suggests the possibility that chemotherapy might be dangerous also in carriers of occult B virus.
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