Hsp90, a key target in cancer therapy, has been identified as the main partner of oleocanthal, an olive oil bioactive compound. A combination of chemical and biological assays disclosed its mechanism of action at the molecular level.
Chemical proteomics-driven discovery of oleocanthal as an Hsp90 inhibitor
MARGARUCCI, LUIGI;MONTI, Maria Chiara;CASSIANO, CHIARA;RICCIO, Raffaele;TOSCO, ALESSANDRA;CASAPULLO, Agostino
2013-01-01
Abstract
Hsp90, a key target in cancer therapy, has been identified as the main partner of oleocanthal, an olive oil bioactive compound. A combination of chemical and biological assays disclosed its mechanism of action at the molecular level.File in questo prodotto:
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