Oxidative stress is a central pathogenic mechanism of Parkinson's disease (PD), and the heme oxygenase (HO) bilirubin pathway is one of the main mammalian antioxidative defences. Indeed, there is growing evidence of HO-bilirubin upregulation from early phases of PD. Our aim was to investigate bilirubin as a possible biomarker of PD diagnosis and progression.

Increased bilirubin levels in de novo Parkinson's disease

PICILLO, MARINA;Erro, R;AMBONI, MARIANNA;PELLECCHIA, MARIA TERESA;BARONE, Paolo;
2015

Abstract

Oxidative stress is a central pathogenic mechanism of Parkinson's disease (PD), and the heme oxygenase (HO) bilirubin pathway is one of the main mammalian antioxidative defences. Indeed, there is growing evidence of HO-bilirubin upregulation from early phases of PD. Our aim was to investigate bilirubin as a possible biomarker of PD diagnosis and progression.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11386/4644195
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