Activated 3-substituted isoindolinones have proved to be efficient nucleophiles in K2CO3-catalyzed Michael reactions of several types of electron-deficient olefins. Moreover, tricyclic pyrrolizidines have been conveniently synthesized via a modification of the described general protocol as a consequence of a cascade Michael=cyclization reaction of unsaturated aldehydes.

3-Carboxylate Substituted Isoindolinones in K2CO3-Catalyzed Michael Reactions

SCORZELLI, FRANCESCO;DI MOLA, ANTONIA;PALOMBI, Laura;FILOSA, Rosanna;MASSA, Antonio
2015-01-01

Abstract

Activated 3-substituted isoindolinones have proved to be efficient nucleophiles in K2CO3-catalyzed Michael reactions of several types of electron-deficient olefins. Moreover, tricyclic pyrrolizidines have been conveniently synthesized via a modification of the described general protocol as a consequence of a cascade Michael=cyclization reaction of unsaturated aldehydes.
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11386/4645585
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 6
  • ???jsp.display-item.citation.isi??? 6
social impact