Activated 3-substituted isoindolinones have proved to be efficient nucleophiles in K2CO3-catalyzed Michael reactions of several types of electron-deficient olefins. Moreover, tricyclic pyrrolizidines have been conveniently synthesized via a modification of the described general protocol as a consequence of a cascade Michael=cyclization reaction of unsaturated aldehydes.
3-Carboxylate Substituted Isoindolinones in K2CO3-Catalyzed Michael Reactions
SCORZELLI, FRANCESCO;DI MOLA, ANTONIA;PALOMBI, Laura;FILOSA, Rosanna;MASSA, Antonio
2015-01-01
Abstract
Activated 3-substituted isoindolinones have proved to be efficient nucleophiles in K2CO3-catalyzed Michael reactions of several types of electron-deficient olefins. Moreover, tricyclic pyrrolizidines have been conveniently synthesized via a modification of the described general protocol as a consequence of a cascade Michael=cyclization reaction of unsaturated aldehydes.File in questo prodotto:
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