The synthesis of the larger resorcin[5 and 6]arene macrocycles OMe and OMe has been realized by a Lewis acid-catalyzed condensation of 1,3-dimethoxy-2-methylbenzene with paraformaldehyde in o-dichlorobenzene as the solvent. The methoxy-resorcin[5 and 6]arenes were quantitatively demethylated by treatment with BBr3 to obtain the corresponding macrocycles with free OH groups. X-ray studies showed that in the solid state both the conformation and the packing of OMe and OMe are driven by C–H···O, C–H···π, and π···π interactions.
|Titolo:||Improved Synthesis of Larger Resorcinarenes|
|Data di pubblicazione:||2016|
|Appare nelle tipologie:||1.1.2 Articolo su rivista con ISSN|