Literature demonstrated the correlation between oxidative stress and pancreatic β cells damage in diabetics. A few reports provided evidence that in animals and humans in vivo, sulphureous mineral water may exert an antioxidant role. The aim of our research was to evaluate the effects of sulphureous SPA therapy on the glycaemic status and the oxidative stress conditions in patients with type 2 diabetes mellitus. The study has been performed on 35 diabetics under drug therapy, randomized in 2 groups: A, who continued drug therapy, and group B, who continued drug therapy in association with a drinking treatment with sulphureous mineral water from Termae of Telese SpA (Benevento-Italy) for 14 days. After 2 weeks of treatments described above were evaluated fasting blood glycaemia; plasma ROM (reactive oxygen metabolites) and BAP (plasma Biological Antioxidant Potential) levels (used d-ROMs test and BAP test - Diacron International srl - Grosseto - Italy). This investigation suggests that combining drug therapy with the drinking of sulphureous water SPA treatment may be useful in type 2 diabetes mellitus for the improvement redox state in the organism.
Hypoglycemic and antioxidant activities of sulphureous mineral water
COSTANTINO, Maria;FILIPPELLI, Amelia;DI GIAMPAOLO, Carlo;RASTRELLI, Luca
2012-01-01
Abstract
Literature demonstrated the correlation between oxidative stress and pancreatic β cells damage in diabetics. A few reports provided evidence that in animals and humans in vivo, sulphureous mineral water may exert an antioxidant role. The aim of our research was to evaluate the effects of sulphureous SPA therapy on the glycaemic status and the oxidative stress conditions in patients with type 2 diabetes mellitus. The study has been performed on 35 diabetics under drug therapy, randomized in 2 groups: A, who continued drug therapy, and group B, who continued drug therapy in association with a drinking treatment with sulphureous mineral water from Termae of Telese SpA (Benevento-Italy) for 14 days. After 2 weeks of treatments described above were evaluated fasting blood glycaemia; plasma ROM (reactive oxygen metabolites) and BAP (plasma Biological Antioxidant Potential) levels (used d-ROMs test and BAP test - Diacron International srl - Grosseto - Italy). This investigation suggests that combining drug therapy with the drinking of sulphureous water SPA treatment may be useful in type 2 diabetes mellitus for the improvement redox state in the organism.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
