Chemical study of the resin of the endemic species Calophyllum pinetorum Bisse [Estudio químico de la resina de la especie endémica Calophyllum pinetorum Bisse]

Objectives: to isolate and identify the main components in the methanolic extract of the resin of the species Calophyllum pinetorum Bisse. Methods: high resolution liquid chromatography was used for the separation of the compounds. Magnetic resonance imaging and mass spectrometry were used for the structural characterization. Results: the separation process allowed the isolation of 3 compounds that were recognized as derivatives of chromans. The compounds 1-3 were identified as calolongic acid, apetalic acid and isoapetalic acid. Conclusions: the presence of chromans corresponds with the studies conducted with other species of this genus, but it is the first time that these compounds are isolated and identified from the same species. On the other hand, it is reported for the first time, too, the presence of chromans in the resin of this genus. © 2008, Editorial Ciencias Médicas.