The synthesis of the first examples of calix[4]arene-based Fischer carbene complexes is reported here. Fischer carbene complex 2 is the key intermediate to reach uracil-like derivatives 3 and 4. X-ray and NMR studies revealed that the uracyl-like synthon gives rise to a supramolecular dimer. The organometallic calixarene complexes showed a promising cytotoxicity towards human tumor cell lines

Installing tungsten Fischer carbene complexes intoa calixarene framework

D'ACUNTO, MARIANTONIETTA;TOMMASONE, STEFANO;TALOTTA, CARMEN;GAETA, CARMINE;NERI, Placido;SPINELLA, Aldo
2016

Abstract

The synthesis of the first examples of calix[4]arene-based Fischer carbene complexes is reported here. Fischer carbene complex 2 is the key intermediate to reach uracil-like derivatives 3 and 4. X-ray and NMR studies revealed that the uracyl-like synthon gives rise to a supramolecular dimer. The organometallic calixarene complexes showed a promising cytotoxicity towards human tumor cell lines
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11386/4673147
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