The expression of calcium/calmodulin-dependent kinase IV (CaMKIV) was hitherto thought to be confined to the nervous system. However, a recent genome-wide analysis indicated an association between hypertension and a single-nucleotide polymorphism (rs10491334) of the human CaMKIV gene (CaMK4), which suggests a role for this kinase in the regulation of vascular tone.

CaMK4 Gene Deletion Induces Hypertension

CIPOLLETTA, ERSILIA;ANASTASIO, ANTONIO;PUCA, Annibale Alessandro;IACCARINO, Guido
2012-01-01

Abstract

The expression of calcium/calmodulin-dependent kinase IV (CaMKIV) was hitherto thought to be confined to the nervous system. However, a recent genome-wide analysis indicated an association between hypertension and a single-nucleotide polymorphism (rs10491334) of the human CaMKIV gene (CaMK4), which suggests a role for this kinase in the regulation of vascular tone.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11386/4697129
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