Abstract It has to be premised that migraine can be, according to our present knowledge, primary or direct, an invalidating disturbance largely spread (>12%) in the world population, having the form of an autonomous disease, as well secondary or indirect (2-3%), in this last case being only a pathologic symptom of different etiologies. We will concentrate our attention on migraine pathogenesis, taking in consideration involved afferent and efferent functions of primary and secondary neurons, with relative neurotransmitters. Furthermore, this review is concerned with the nature, type and proposed mechanisms of migraine pain as well as recent clinical investigations .
Novel Therapeutic Investigations in Migraine Pain
Capasso A
2017
Abstract
Abstract It has to be premised that migraine can be, according to our present knowledge, primary or direct, an invalidating disturbance largely spread (>12%) in the world population, having the form of an autonomous disease, as well secondary or indirect (2-3%), in this last case being only a pathologic symptom of different etiologies. We will concentrate our attention on migraine pathogenesis, taking in consideration involved afferent and efferent functions of primary and secondary neurons, with relative neurotransmitters. Furthermore, this review is concerned with the nature, type and proposed mechanisms of migraine pain as well as recent clinical investigations .I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
