Discovered more than one decade ago, α,α-diaryl prolinols, most of them commercially available compounds, demonstrated to be distinctive organocatalysts in asymmetric synthesis. Their application successfully spanned across different carbon-carbon or carbon-heteroatom bond forming reactions and cascade processes, exploiting covalent and noncovalent activation of the reagents. In this minireview, the advances from 2013 up to the end of 2018 in α,α-diaryl prolinols promoted stereoselective catalysis and synthesis of biologically active compounds, are illustrated.

Diaryl Prolinols in Stereoselective Catalysis and Synthesis: An Update

Meninno S.
;
Volpe C.;Lattanzi A.
2019-01-01

Abstract

Discovered more than one decade ago, α,α-diaryl prolinols, most of them commercially available compounds, demonstrated to be distinctive organocatalysts in asymmetric synthesis. Their application successfully spanned across different carbon-carbon or carbon-heteroatom bond forming reactions and cascade processes, exploiting covalent and noncovalent activation of the reagents. In this minireview, the advances from 2013 up to the end of 2018 in α,α-diaryl prolinols promoted stereoselective catalysis and synthesis of biologically active compounds, are illustrated.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11386/4727733
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