Mastocytosis is a rare disease characterized by clonal proliferation of mast cells in different organs. Clinical manifestations of mastocytosis are mostly due to the release of mediators from mast cells and, in many cases such as urticaria, flushing, angioedema and anaphylaxis, are expression of biological effects of mediators on endothelial cells. Chronic secretion of mediators in patients with mastocytosis may lead to alteration of endothelial function.
Flow mediated dilation shows impaired endothelial function in patients with mastocytosis
Bucci, Tommaso;Parente, Roberta;De Feo, Giulia;Cardamone, Chiara;Triggiani, Massimo
2019-01-01
Abstract
Mastocytosis is a rare disease characterized by clonal proliferation of mast cells in different organs. Clinical manifestations of mastocytosis are mostly due to the release of mediators from mast cells and, in many cases such as urticaria, flushing, angioedema and anaphylaxis, are expression of biological effects of mediators on endothelial cells. Chronic secretion of mediators in patients with mastocytosis may lead to alteration of endothelial function.File in questo prodotto:
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