The effects of GRK2 inhibition on myocardial metabolism in heart failure (HF) are unchartered. In this work, we evaluated the impact of pharmacological inhibition of GRK2 by a cyclic peptide, C7, on metabolic, biochemical, and functional phenotypes in experimental HF.
Pharmacological inhibition of GRK2 improves cardiac metabolism and function in experimental heart failure
Ciccarelli, Michele;Sala, Marina;Bertamino, Alessia;Campiglia, Pietro;Oliveti, Marco;
2020-01-01
Abstract
The effects of GRK2 inhibition on myocardial metabolism in heart failure (HF) are unchartered. In this work, we evaluated the impact of pharmacological inhibition of GRK2 by a cyclic peptide, C7, on metabolic, biochemical, and functional phenotypes in experimental HF.File in questo prodotto:
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