In this work, we report a facile access to a 3,3-disubstituted isoindolinone by means of Krapcho decarboxylation reaction of the respective substituted dimethyl malonate derivative. Good isolated yields were obtained under mild reaction conditions.
Methyl 2-(1-methyl-3-oxoisoindolin-1-yl)acetate
Di Mola A.;Macchia A.;Palombi L.;Massa A.
2020-01-01
Abstract
In this work, we report a facile access to a 3,3-disubstituted isoindolinone by means of Krapcho decarboxylation reaction of the respective substituted dimethyl malonate derivative. Good isolated yields were obtained under mild reaction conditions.File in questo prodotto:
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