We report a rapid and cost-effective system to analyze morphological properties and 3D alignment positions of human white blood cell in a viscoelastic induced microfluidic flow. Measurements have been performed in physiological conditions using light scattering for the investigation of the individu-al cell properties and digital holography for the accurate tracking of the cell position in 3D. Our re-sults confirm the possibility to obtain sub-micrometric individual cell details as dimension and refrac-tive index, together with detailed cell location in continuous measurement flows inside of a rectangular shaped channel.

Characterization and 3D-localization of human white blood cells in microfluidic flows

Rossi D.;
2016-01-01

Abstract

We report a rapid and cost-effective system to analyze morphological properties and 3D alignment positions of human white blood cell in a viscoelastic induced microfluidic flow. Measurements have been performed in physiological conditions using light scattering for the investigation of the individu-al cell properties and digital holography for the accurate tracking of the cell position in 3D. Our re-sults confirm the possibility to obtain sub-micrometric individual cell details as dimension and refrac-tive index, together with detailed cell location in continuous measurement flows inside of a rectangular shaped channel.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11386/4823583
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