Optically pure 3,4-dihydroquinoxalin-2-ones, being members of the privileged quinoxaline family, received significant interest in organic synthesis, more particularly in medicinal chemistry. This perspective aims to showcase the state of art of asymmetric approaches developed to prepare 3,4-dihydroquinoxalin-2-ones with a focus on catalytic routes, highlighting challenges and opportunities for future developments.
3,4-Dihydroquinoxalin-2-one privileged motif: A journey from classical chiral tools based synthesis to modern catalytic enantioselective strategies
Lattanzi, Alessandra
2022-01-01
Abstract
Optically pure 3,4-dihydroquinoxalin-2-ones, being members of the privileged quinoxaline family, received significant interest in organic synthesis, more particularly in medicinal chemistry. This perspective aims to showcase the state of art of asymmetric approaches developed to prepare 3,4-dihydroquinoxalin-2-ones with a focus on catalytic routes, highlighting challenges and opportunities for future developments.File in questo prodotto:
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