Sorption of dicarboxylic acid molecules of pharmaceutical interest such as azelaic acid (AzA), in syndiotactic polystyrene (sPS) films presenting δ and ε nanoporous crystalline structure, is reported. Fourier Transform Infrared (FTIR), Polarized FTIR and Wide-Angle X-ray diffraction (WAXD) patterns on axially oriented sPS films has been performed to verify their sorption in crystalline lattices resulting in the formation of co-crystalline (CC) phases. Experimental evidence provides that AzA molecules can be included in the crystalline nanochannels of ε phase both as isolated and hydrogen-bonded molecules whereas they are only dissolved in the amorphous phase of δ samples.

Co-Crystalline Phases of Syndiotactic Polystyrene with Azelaic Acid Molecules of Pharmaceutical Interest

Cozzolino A.
;
Daniel C.;Rizzo P.
2024-01-01

Abstract

Sorption of dicarboxylic acid molecules of pharmaceutical interest such as azelaic acid (AzA), in syndiotactic polystyrene (sPS) films presenting δ and ε nanoporous crystalline structure, is reported. Fourier Transform Infrared (FTIR), Polarized FTIR and Wide-Angle X-ray diffraction (WAXD) patterns on axially oriented sPS films has been performed to verify their sorption in crystalline lattices resulting in the formation of co-crystalline (CC) phases. Experimental evidence provides that AzA molecules can be included in the crystalline nanochannels of ε phase both as isolated and hydrogen-bonded molecules whereas they are only dissolved in the amorphous phase of δ samples.
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11386/4884974
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 0
  • ???jsp.display-item.citation.isi??? ND
social impact