In this contribution, the synthesis and the reactivity with HS− of a family of half-salen Zn complexes are reported. We provide evidence that HS− binds the zinc center of all the complexes under investigation. DFT and CCSD(T) calculations were performed to model the reactivity of these complexes with HS−. We successfully applied a homoleptic zinc complex bearing a Schiff-based ligand with pyridine pendant arms as a probe for the monitoring of exogenous and endogenous H2S levels in live cells.

Fluorescent half-salen phenoxy-imine zinc complexes to reveal exogenous and endogenous H2S

Trerotola A.;Gravina G.;Vykhovanets V.;Blal N.;Guarnieri D.;Lamberti M.;Mazzeo M.;Strianese M.
2025

Abstract

In this contribution, the synthesis and the reactivity with HS− of a family of half-salen Zn complexes are reported. We provide evidence that HS− binds the zinc center of all the complexes under investigation. DFT and CCSD(T) calculations were performed to model the reactivity of these complexes with HS−. We successfully applied a homoleptic zinc complex bearing a Schiff-based ligand with pyridine pendant arms as a probe for the monitoring of exogenous and endogenous H2S levels in live cells.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11386/4903875
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