CIAGLIA, TANIA
CIAGLIA, TANIA
Dipartimento di Farmacia/DIFARMA
A Comprehensive In Vitro Characterization of a New Class of Indole-Based Compounds Developed as Selective Haspin Inhibitors
2024-01-01 Vestuto, Vincenzo; Ciaglia, Tania; Musella, Simona; Di Sarno, Veronica; Smaldone, Gerardina; Di Matteo, Francesca; Scala, Maria Carmina; Napolitano, Valeria; Miranda, Maria Rosaria; Amodio, Giuseppina; Novi, Sara; Pepe, Giacomo; Basilicata, Manuela Giovanna; Gazzillo, Erica; Pace, Simona; Gomez-Monterrey, Isabel M.; Sala, Marina; Bifulco, Giuseppe; Tecce, Mario Felice; Campiglia, Pietro; Ostacolo, Carmine; Lauro, Gianluigi; Manfra, Michele; Bertamino, Alessia
An Efficient Approach to Aromatic Aminomethylation Using Dichloromethane as Methylene Source
2019-01-01 Ostacolo, Carmine; DI SARNO, Veronica; Musella, Simona; Ciaglia, Tania; Vestuto, Vincenzo; Pepe, Giacomo; Merciai, Fabrizio; Campiglia, Pietro; Monterrey Isabel M., Gomez; Bertamino, Alessia
Anticancer Therapies Based on Oxidative Damage: Lycium barbarum Inhibits the Proliferation of MCF-7 Cells by Activating Pyroptosis through Endoplasmic Reticulum Stress
2024-01-01 Miranda, Maria Rosaria; Basilicata, Manuela Giovanna; Vestuto, Vincenzo; Aquino, Giovanna; Marino, Pasquale; Salviati, Emanuela; Ciaglia, Tania; Domínguez-Rodríguez, Gloria; Moltedo, Ornella; Campiglia, Pietro; Pepe, Giacomo; Manfra, Michele
Beyond Retigabine: Design, Synthesis, and Pharmacological Characterization of a Potent and Chemically Stable Neuronal Kv7 Channel Activator with Anticonvulsant Activity
2022-01-01 Musella, Simona; Carotenuto, Lidia; Iraci, Nunzio; Baroli, Giulia; Ciaglia, Tania; Nappi, Piera; Basilicata, MANUELA GIOVANNA; Salviati, Emanuela; Barrese, Vincenzo; Vestuto, Vincenzo; Pignataro, Giuseppe; Pepe, Giacomo; Sommella, EDUARDO MARIA; DI SARNO, Veronica; Manfra, Michele; Campiglia, Pietro; Gomez-Monterrey, Isabel; Bertamino, Alessia; Taglialatela, Maurizio; Ostacolo, Carmine; Francesco Miceli, And
Continuous-flow synthesis of thiazolidine libraries: one-pot two steps protocol optimization
2015-01-01 Tania, Ciaglia; Ostacolo, Carmine; Alessia, Bertamino; Veronica Di, Sarno; Musella, Simona; GOMEZ MONTERREY, ISABEL MARIA; Novellino, Ettore; Pietro, Campiglia
Correction: Utilization of fluoroform for difluoromethylation in continuous flow: a concise synthesis of α-difluoromethyl-amino acids
2023-01-01 Köckinger, Manuel; Ciaglia, Tania; Bersier, Michael; Hanselmann, Paul; Gutmann, Bernhard; Oliver Kappe, C.
Design and 3D printing of a stainless steel reactor for continuous difluoromethylations using fluoroform
2017-01-01 Gutmann, Bernhard; Köckinger, Manuel; Glotz, Gabriel; Ciaglia, Tania; Slama, Eyke; Zadravec, Matej; Pfanner, Stefan; Maier, Manuel C.; Gruber-Wölfler, Heidrun; Oliver Kappe, C.
Design, Synthesis, and Pharmacological Characterization of a Potent Soluble Epoxide Hydrolase Inhibitor for the Treatment of Acute Pancreatitis
2023-01-01 Musella, Simona; D'Avino, Danilo; Peltner, Lukas Klaus; Di Sarno, Veronica; Cerqua, Ida; Merciai, Fabrizio; Vestuto, Vincenzo; Ciaglia, Tania; Smaldone, Gerardina; Di Matteo, Francesca; Di Micco, Simone; Napolitano, Valeria; Bifulco, Giuseppe; Pepe, Giacomo; Sommella, Eduardo Maria; Basilicata, Manuela Giovanna; Aquino, Giovanna; Gomez-Monterrey, Isabel M; Campiglia, Pietro; Ostacolo, Carmine; Roviezzo, Fiorentina; Werz, Oliver; Rossi, Antonietta; Bertamino, Alessia
Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization
2022-01-01 Cerqua, Ida; Musella, Simona; Peltner, Lukas Klaus; D'Avino, Danilo; Di Sarno, Veronica; Granato, Elisabetta; Vestuto, Vincenzo; Di Matteo, Rita; Pace, Simona; Ciaglia, Tania; Bilancia, Rossella; Smaldone, Gerardina; Di Matteo, Francesca; Di Micco, Simone; Bifulco, Giuseppe; Pepe, Giacomo; Basilicata, Manuela Giovanna; Rodriquez, Manuela; Gomez-Monterrey, Isabel M; Campiglia, Pietro; Ostacolo, Carmine; Roviezzo, Fiorentina; Werz, Oliver; Rossi, Antonietta; Bertamino, Alessia
DTNQ-based anticancer derivatives as selective glucose penetration inhibitors
2015-01-01 Musella, Simona; Alessia, Bertamino; Ostacolo, Carmine; Veronica Di, Sarno; Tania, Ciaglia; Novellino, Ettore; Pietro, Campiglia; GOMEZ MONTERREY, ISABEL MARIA
Exploration of TRPM8 Binding Sites by β-Carboline-Based Antagonists and Their in Vitro Characterization and in Vivo Analgesic Activities
2020-01-01 Bertamino, A.; Ostacolo, C.; Medina, A.; Di Sarno, V.; Lauro, G.; Ciaglia, T.; Vestuto, V.; Pepe, G.; Basilicata, M. G.; Musella, S.; Smaldone, G.; Cristiano, C.; Gonzalez-Rodriguez, S.; Fernandez-Carvajal, A.; Bifulco, G.; Campiglia, P.; Gomez-Monterrey, I.; Russo, R.
Identification of a dual acting SARS-CoV-2 proteases inhibitor through in silico design and step-by-step biological characterization
2021-01-01 Di Sarno, V.; Lauro, G.; Musella, S.; Ciaglia, T.; Vestuto, V.; Sala, M.; Scala, M. C.; Smaldone, G.; Di Matteo, F.; Novi, S.; Tecce, M. F.; Moltedo, O.; Bifulco, G.; Campiglia, P.; Gomez-Monterrey, I. M.; Snoeck, R.; Andrei, G.; Ostacolo, C.; Bertamino, A.
Identification of a Potent Tryptophan-Based TRPM8 Antagonist with in Vivo Analgesic Activity
2018-01-01 Bertamino, Alessia; Iraci, Nunzio; Ostacolo, Carmine; Ambrosino, Paolo; Musella, Simona; Di Sarno, Veronica; Ciaglia, Tania; Pepe, Giacomo; Sala, Marina; Soldovieri, Maria Virginia; Mosca, Ilaria; Gonzalez-Rodriguez, Sara; Fernandez-Carvajal, Asia; Ferrer-Montiel, Antonio; Novellino, Ettore; Taglialatela, Maurizio; Campiglia, Pietro; Gomez-Monterrey, Isabel
Identification of an indol-based derivative as potent and selective varicella zoster virus (VZV) inhibitor
2016-01-01 Musella, Simona; DI SARNO, Veronica; Ciaglia, Tania; Sala, Marina; Spensiero, Antonia; Scala, MARIA CARMINA; Ostacolo, Carmine; Andrei, Graciela; Balzarini, Jan; Snoeck, Robert; Novellino, Ettore; Campiglia, Pietro; Bertamino, Alessia; Gomez Monterrey, Isabel M.
Identification of an indol-based multi-target kinase inhibitor through phenotype screening and target fishing using inverse virtual screening approach
2019-01-01 Ostacolo, Carmine; Di Sarno, Veronica; Lauro, Gianluigi; Pepe, Giacomo; Musella, Simona; Ciaglia, Tania; Vestuto, Vincenzo; Autore, Giuseppina; Bifulco, Giuseppe; Marzocco, Stefania; Campiglia, Pietro; Gomez-Monterrey, Isabel M; Bertamino, Alessia
In Silico Assisted Identification, Synthesis, and In Vitro Pharmacological Characterization of Potent and Selective Blockers of the Epilepsy-Associated KCNT1 Channel
2024-01-01 Iraci, Nunzio; Carotenuto, Lidia; Ciaglia, Tania; Belperio, Giorgio; Di Matteo, Francesca; Mosca, Ilaria; Carleo, Giusy; Giovanna Basilicata, Manuela; Ambrosino, Paolo; Turcio, Rita; Puzo, Deborah; Pepe, Giacomo; Gomez-Monterrey, Isabel; Soldovieri, Maria Virginia; Di Sarno, Veronica; Campiglia, Pietro; Miceli, Francesco; Bertamino, Alessia; Ostacolo, Carmine; Taglialatela, Maurizio
In Silico Identification and In Vitro Evaluation of New ABCG2 Transporter Inhibitors as Potential Anticancer Agents
2022-01-01 Di Micco, Simone; Di Sarno, Veronica; Rossi, Martina; Vestuto, Vincenzo; Konno, Takumi; Novi, Sara; Tecce, Mario Felice; Napolitano, Valeria; Ciaglia, Tania; Vitale, Andrea; Gomez-Monterrey, Isabel Maria; Bifulco, Giuseppe; Bertamino, Alessia; Ostacolo, Carmine; Blasi, Paolo; Fasano, Alessio; Campiglia, Pietro; Musella, Simona
In Silico Methods for the Discovery of Kv7.2/7.3 Channels Modulators: A Comprehensive Review
2024-01-01 Stagno, Claudio; Mancuso, Francesca; Ciaglia, Tania; Ostacolo, Carmine; Piperno, Anna; Iraci, Nunzio; Micale, Nicola
In Vitro and In Vivo Pharmacological Characterization of a Novel TRPM8 Inhibitor Chemotype Identified by Small-Scale Preclinical Screening
2022-01-01 Iraci, Nunzio; Ostacolo, Carmine; Medina-Peris, Alicia; Ciaglia, Tania; Novoselov, Anton M.; Altieri, Andrea; Cabañero, David; Fernandez-Carvajal, Asia; Campiglia, Pietro; Gomez-Monterrey, Isabel; Bertamino, Alessia; Kurkin, Alexander V.
KCNT1 Channel Blockers: A Medicinal Chemistry Perspective
2024-01-01 Di Matteo, Francesca; Mancuso, Francesca; Turcio, Rita; Ciaglia, Tania; Stagno, Claudio; Di Chio, Carla; Campiglia, Pietro; Bertamino, Alessia; Giofrè, Salvatore Vincenzo; Ostacolo, Carmine; Iraci, Nunzio
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A Comprehensive In Vitro Characterization of a New Class of Indole-Based Compounds Developed as Selective Haspin Inhibitors | 1-gen-2024 | Vestuto, Vincenzo; Ciaglia, Tania; Musella, Simona; Di Sarno, Veronica; Smaldone, Gerardina; Di Matteo, Francesca; Scala, Maria Carmina; Napolitano, Valeria; Miranda, Maria Rosaria; Amodio, Giuseppina; Novi, Sara; Pepe, Giacomo; Basilicata, Manuela Giovanna; Gazzillo, Erica; Pace, Simona; Gomez-Monterrey, Isabel M.; Sala, Marina; Bifulco, Giuseppe; Tecce, Mario Felice; Campiglia, Pietro; Ostacolo, Carmine; Lauro, Gianluigi; Manfra, Michele; Bertamino, Alessia | |
| An Efficient Approach to Aromatic Aminomethylation Using Dichloromethane as Methylene Source | 1-gen-2019 | Ostacolo, Carmine; DI SARNO, Veronica; Musella, Simona; Ciaglia, Tania; Vestuto, Vincenzo; Pepe, Giacomo; Merciai, Fabrizio; Campiglia, Pietro; Monterrey Isabel M., Gomez; Bertamino, Alessia | |
| Anticancer Therapies Based on Oxidative Damage: Lycium barbarum Inhibits the Proliferation of MCF-7 Cells by Activating Pyroptosis through Endoplasmic Reticulum Stress | 1-gen-2024 | Miranda, Maria Rosaria; Basilicata, Manuela Giovanna; Vestuto, Vincenzo; Aquino, Giovanna; Marino, Pasquale; Salviati, Emanuela; Ciaglia, Tania; Domínguez-Rodríguez, Gloria; Moltedo, Ornella; Campiglia, Pietro; Pepe, Giacomo; Manfra, Michele | |
| Beyond Retigabine: Design, Synthesis, and Pharmacological Characterization of a Potent and Chemically Stable Neuronal Kv7 Channel Activator with Anticonvulsant Activity | 1-gen-2022 | Musella, Simona; Carotenuto, Lidia; Iraci, Nunzio; Baroli, Giulia; Ciaglia, Tania; Nappi, Piera; Basilicata, MANUELA GIOVANNA; Salviati, Emanuela; Barrese, Vincenzo; Vestuto, Vincenzo; Pignataro, Giuseppe; Pepe, Giacomo; Sommella, EDUARDO MARIA; DI SARNO, Veronica; Manfra, Michele; Campiglia, Pietro; Gomez-Monterrey, Isabel; Bertamino, Alessia; Taglialatela, Maurizio; Ostacolo, Carmine; Francesco Miceli, And | |
| Continuous-flow synthesis of thiazolidine libraries: one-pot two steps protocol optimization | 1-gen-2015 | Tania, Ciaglia; Ostacolo, Carmine; Alessia, Bertamino; Veronica Di, Sarno; Musella, Simona; GOMEZ MONTERREY, ISABEL MARIA; Novellino, Ettore; Pietro, Campiglia | |
| Correction: Utilization of fluoroform for difluoromethylation in continuous flow: a concise synthesis of α-difluoromethyl-amino acids | 1-gen-2023 | Köckinger, Manuel; Ciaglia, Tania; Bersier, Michael; Hanselmann, Paul; Gutmann, Bernhard; Oliver Kappe, C. | |
| Design and 3D printing of a stainless steel reactor for continuous difluoromethylations using fluoroform | 1-gen-2017 | Gutmann, Bernhard; Köckinger, Manuel; Glotz, Gabriel; Ciaglia, Tania; Slama, Eyke; Zadravec, Matej; Pfanner, Stefan; Maier, Manuel C.; Gruber-Wölfler, Heidrun; Oliver Kappe, C. | |
| Design, Synthesis, and Pharmacological Characterization of a Potent Soluble Epoxide Hydrolase Inhibitor for the Treatment of Acute Pancreatitis | 1-gen-2023 | Musella, Simona; D'Avino, Danilo; Peltner, Lukas Klaus; Di Sarno, Veronica; Cerqua, Ida; Merciai, Fabrizio; Vestuto, Vincenzo; Ciaglia, Tania; Smaldone, Gerardina; Di Matteo, Francesca; Di Micco, Simone; Napolitano, Valeria; Bifulco, Giuseppe; Pepe, Giacomo; Sommella, Eduardo Maria; Basilicata, Manuela Giovanna; Aquino, Giovanna; Gomez-Monterrey, Isabel M; Campiglia, Pietro; Ostacolo, Carmine; Roviezzo, Fiorentina; Werz, Oliver; Rossi, Antonietta; Bertamino, Alessia | |
| Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization | 1-gen-2022 | Cerqua, Ida; Musella, Simona; Peltner, Lukas Klaus; D'Avino, Danilo; Di Sarno, Veronica; Granato, Elisabetta; Vestuto, Vincenzo; Di Matteo, Rita; Pace, Simona; Ciaglia, Tania; Bilancia, Rossella; Smaldone, Gerardina; Di Matteo, Francesca; Di Micco, Simone; Bifulco, Giuseppe; Pepe, Giacomo; Basilicata, Manuela Giovanna; Rodriquez, Manuela; Gomez-Monterrey, Isabel M; Campiglia, Pietro; Ostacolo, Carmine; Roviezzo, Fiorentina; Werz, Oliver; Rossi, Antonietta; Bertamino, Alessia | |
| DTNQ-based anticancer derivatives as selective glucose penetration inhibitors | 1-gen-2015 | Musella, Simona; Alessia, Bertamino; Ostacolo, Carmine; Veronica Di, Sarno; Tania, Ciaglia; Novellino, Ettore; Pietro, Campiglia; GOMEZ MONTERREY, ISABEL MARIA | |
| Exploration of TRPM8 Binding Sites by β-Carboline-Based Antagonists and Their in Vitro Characterization and in Vivo Analgesic Activities | 1-gen-2020 | Bertamino, A.; Ostacolo, C.; Medina, A.; Di Sarno, V.; Lauro, G.; Ciaglia, T.; Vestuto, V.; Pepe, G.; Basilicata, M. G.; Musella, S.; Smaldone, G.; Cristiano, C.; Gonzalez-Rodriguez, S.; Fernandez-Carvajal, A.; Bifulco, G.; Campiglia, P.; Gomez-Monterrey, I.; Russo, R. | |
| Identification of a dual acting SARS-CoV-2 proteases inhibitor through in silico design and step-by-step biological characterization | 1-gen-2021 | Di Sarno, V.; Lauro, G.; Musella, S.; Ciaglia, T.; Vestuto, V.; Sala, M.; Scala, M. C.; Smaldone, G.; Di Matteo, F.; Novi, S.; Tecce, M. F.; Moltedo, O.; Bifulco, G.; Campiglia, P.; Gomez-Monterrey, I. M.; Snoeck, R.; Andrei, G.; Ostacolo, C.; Bertamino, A. | |
| Identification of a Potent Tryptophan-Based TRPM8 Antagonist with in Vivo Analgesic Activity | 1-gen-2018 | Bertamino, Alessia; Iraci, Nunzio; Ostacolo, Carmine; Ambrosino, Paolo; Musella, Simona; Di Sarno, Veronica; Ciaglia, Tania; Pepe, Giacomo; Sala, Marina; Soldovieri, Maria Virginia; Mosca, Ilaria; Gonzalez-Rodriguez, Sara; Fernandez-Carvajal, Asia; Ferrer-Montiel, Antonio; Novellino, Ettore; Taglialatela, Maurizio; Campiglia, Pietro; Gomez-Monterrey, Isabel | |
| Identification of an indol-based derivative as potent and selective varicella zoster virus (VZV) inhibitor | 1-gen-2016 | Musella, Simona; DI SARNO, Veronica; Ciaglia, Tania; Sala, Marina; Spensiero, Antonia; Scala, MARIA CARMINA; Ostacolo, Carmine; Andrei, Graciela; Balzarini, Jan; Snoeck, Robert; Novellino, Ettore; Campiglia, Pietro; Bertamino, Alessia; Gomez Monterrey, Isabel M. | |
| Identification of an indol-based multi-target kinase inhibitor through phenotype screening and target fishing using inverse virtual screening approach | 1-gen-2019 | Ostacolo, Carmine; Di Sarno, Veronica; Lauro, Gianluigi; Pepe, Giacomo; Musella, Simona; Ciaglia, Tania; Vestuto, Vincenzo; Autore, Giuseppina; Bifulco, Giuseppe; Marzocco, Stefania; Campiglia, Pietro; Gomez-Monterrey, Isabel M; Bertamino, Alessia | |
| In Silico Assisted Identification, Synthesis, and In Vitro Pharmacological Characterization of Potent and Selective Blockers of the Epilepsy-Associated KCNT1 Channel | 1-gen-2024 | Iraci, Nunzio; Carotenuto, Lidia; Ciaglia, Tania; Belperio, Giorgio; Di Matteo, Francesca; Mosca, Ilaria; Carleo, Giusy; Giovanna Basilicata, Manuela; Ambrosino, Paolo; Turcio, Rita; Puzo, Deborah; Pepe, Giacomo; Gomez-Monterrey, Isabel; Soldovieri, Maria Virginia; Di Sarno, Veronica; Campiglia, Pietro; Miceli, Francesco; Bertamino, Alessia; Ostacolo, Carmine; Taglialatela, Maurizio | |
| In Silico Identification and In Vitro Evaluation of New ABCG2 Transporter Inhibitors as Potential Anticancer Agents | 1-gen-2022 | Di Micco, Simone; Di Sarno, Veronica; Rossi, Martina; Vestuto, Vincenzo; Konno, Takumi; Novi, Sara; Tecce, Mario Felice; Napolitano, Valeria; Ciaglia, Tania; Vitale, Andrea; Gomez-Monterrey, Isabel Maria; Bifulco, Giuseppe; Bertamino, Alessia; Ostacolo, Carmine; Blasi, Paolo; Fasano, Alessio; Campiglia, Pietro; Musella, Simona | |
| In Silico Methods for the Discovery of Kv7.2/7.3 Channels Modulators: A Comprehensive Review | 1-gen-2024 | Stagno, Claudio; Mancuso, Francesca; Ciaglia, Tania; Ostacolo, Carmine; Piperno, Anna; Iraci, Nunzio; Micale, Nicola | |
| In Vitro and In Vivo Pharmacological Characterization of a Novel TRPM8 Inhibitor Chemotype Identified by Small-Scale Preclinical Screening | 1-gen-2022 | Iraci, Nunzio; Ostacolo, Carmine; Medina-Peris, Alicia; Ciaglia, Tania; Novoselov, Anton M.; Altieri, Andrea; Cabañero, David; Fernandez-Carvajal, Asia; Campiglia, Pietro; Gomez-Monterrey, Isabel; Bertamino, Alessia; Kurkin, Alexander V. | |
| KCNT1 Channel Blockers: A Medicinal Chemistry Perspective | 1-gen-2024 | Di Matteo, Francesca; Mancuso, Francesca; Turcio, Rita; Ciaglia, Tania; Stagno, Claudio; Di Chio, Carla; Campiglia, Pietro; Bertamino, Alessia; Giofrè, Salvatore Vincenzo; Ostacolo, Carmine; Iraci, Nunzio |