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EnglishAdrenalin (5.0 x 10-5 M) increased gill vascular resistance up to 23.2 ± 6.8% in the isolated and perfused head of the european eel (Anguilla anguilla L.). This vasoactive response is nearly abolished by the α-adrenergic blocking agent phentolamine mesylate (5.0 x 10-5 M), while it is increased by the β-blocker propranolol (5.0 x 10-4 M). From these results it may be inferred that, in our experimental conditions, the major response to the catecholamine is a vasoconstriction mediated via α-adrenoceptors.
http://hdl.handle.net/11386/3131718| Titolo: | Vasoconstrictory effects of adrenalin on the perfused head of the eel (Anguilla anguilla L.) |
| Autori interni: | PINTO, Aldo |
| Data di pubblicazione: | 1983 |
| Rivista: | COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY. C, COMPARATIVE PHARMACOLOGY AND TOXICOLOGY |
| Abstract: | Adrenalin (5.0 x 10-5 M) increased gill vascular resistance up to 23.2 ± 6.8% in the isolated and perfused head of the european eel (Anguilla anguilla L.). This vasoactive response is nearly abolished by the α-adrenergic blocking agent phentolamine mesylate (5.0 x 10-5 M), while it is increased by the β-blocker propranolol (5.0 x 10-4 M). From these results it may be inferred that, in our experimental conditions, the major response to the catecholamine is a vasoconstriction mediated via α-adrenoceptors. |
| Handle: | http://hdl.handle.net/11386/3131718 |
| Appare nelle tipologie: | 1.1 Articoli su Rivista |
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