Hemodynamic and ventilatory effects of i.v. administration of salbutamol (3 micrograms/kg body weight) have been studied in 6 patients affected by chronic obstructive lung disease. A fall of mean pulmonary arterial pressure (PAP), pulmonary vascular resistances index (PVRI), left ventricular end-diastolic pressure (LVEDP) and systemic vascular resistances index (SVRI) have been found significant. Furthermore, heart rate (HR), cardiac index (CI) and left ventricle dp/dt max (LV dp/dt max) were early and remarkably increased. At 30 min after drug administration such effects disappeared in all patients. Regarding the ventilatory data, the authors assume that a significant and precocious FEV1 and vital capacity increase was still present at 30 min. Hemodynamic effects can be related to either an increased venous return due to peripheral vasodilatation or to a beta 1-cardiac receptor stimulation

Hemodynamic and ventilatoryeffects of intravenous salbutamol in patients affected by cold.

PISCIONE, Federico;
1980

Abstract

Hemodynamic and ventilatory effects of i.v. administration of salbutamol (3 micrograms/kg body weight) have been studied in 6 patients affected by chronic obstructive lung disease. A fall of mean pulmonary arterial pressure (PAP), pulmonary vascular resistances index (PVRI), left ventricular end-diastolic pressure (LVEDP) and systemic vascular resistances index (SVRI) have been found significant. Furthermore, heart rate (HR), cardiac index (CI) and left ventricle dp/dt max (LV dp/dt max) were early and remarkably increased. At 30 min after drug administration such effects disappeared in all patients. Regarding the ventilatory data, the authors assume that a significant and precocious FEV1 and vital capacity increase was still present at 30 min. Hemodynamic effects can be related to either an increased venous return due to peripheral vasodilatation or to a beta 1-cardiac receptor stimulation
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11386/3497477
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact