A chemoenzymatic approach to some musk macrolactones has been explored by the optimization of macrolactonization catalyzed by Candida antarctica lipase B (Novozym 435). This fast and high yield optimized methodology represents a large improvement to previously reported results. The methodology was applied to the preparation of 16-hexadecanolide, exaltolide, ambrettolide and (15R)-15-hexadecanolide

Chemoenzymatic preparation of musky macrolactones

D'ACUNTO, MARIANTONIETTA;CARUSO, Tonino;SPINELLA, Aldo
2015

Abstract

A chemoenzymatic approach to some musk macrolactones has been explored by the optimization of macrolactonization catalyzed by Candida antarctica lipase B (Novozym 435). This fast and high yield optimized methodology represents a large improvement to previously reported results. The methodology was applied to the preparation of 16-hexadecanolide, exaltolide, ambrettolide and (15R)-15-hexadecanolide
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11386/4643698
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