Poly(ADP-ribose) polymerase 1 (PARP-1) activity has been implicated in the pathogenesis of numerous diseases as cancer, inflammation, diabetes and neurodegenerative disorders, therefore the research for new PARP-1 inhibitors is still an active area.
Identification and mechanism of action analysis of the new PARP-1 inhibitor 2″-hydroxygenkwanol A
DAL PIAZ, FABRIZIO;FERRO, PIERA;VASATURO, MICHELE;FORTE, GIOVANNI;CHINI, MARIA GIOVANNA;BIFULCO, Giuseppe;TOSCO, ALESSANDRA;DE TOMMASI, Nunziatina
2015
Abstract
Poly(ADP-ribose) polymerase 1 (PARP-1) activity has been implicated in the pathogenesis of numerous diseases as cancer, inflammation, diabetes and neurodegenerative disorders, therefore the research for new PARP-1 inhibitors is still an active area.File in questo prodotto:
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