The paper proposes a numerical model for T-cell dynamics, based on a reaction-diffusion problem originated by adding a diffusion term in the model introduced in [1] and based on ordinary differential equations. The model here introduced is specifically intended to provide a mathematical description of the homeostasis of T-cells, mainly due to a quorum-sensing mechanism. The introduced reaction-diffusion problem is then discretized by means of a finite difference numerical scheme. Numerical experiments supporting the approach are provided.

Numerical modeling of T-cell dynamics by reaction-diffusion problems

D'AMBROSIO, RAFFAELE;PATERNOSTER, Beatrice;
2016-01-01

Abstract

The paper proposes a numerical model for T-cell dynamics, based on a reaction-diffusion problem originated by adding a diffusion term in the model introduced in [1] and based on ordinary differential equations. The model here introduced is specifically intended to provide a mathematical description of the homeostasis of T-cells, mainly due to a quorum-sensing mechanism. The introduced reaction-diffusion problem is then discretized by means of a finite difference numerical scheme. Numerical experiments supporting the approach are provided.
2016
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11386/4678771
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